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Research findings reveal new approach to prevent age-related obesity

The function and distribution of adipose tissue in the body change during the course of life. Beige fat cells, a special type of adipocytes, have the capability to use energy reserves - fatty deposits - by generating heat in a process known as thermogenesis.

4 May 2017

Study finds no increase in muscle-related symptoms when patients are unaware of taking statin therapy

When patients were unaware they were taking statins there was no reported increase in muscle-related symptoms. But, when patients knew they were taking a statin, they were more likely to report symptoms, a finding consistent with the nocebo effect.

4 May 2017

Synthetic biologists re-engineer yeast cells to manufacture antibiotic penicillin

The synthetic biologists from Imperial College London have re-engineered yeast cells to manufacture the nonribosomal peptide antibiotic penicillin. In laboratory experiments, they were able to demonstrate that this yeast had antibacterial properties against streptococcus bacteria.

4 May 2017

New poster presented at ASCB shows power of Phasefocus’ Livecyte label-free cell analysis system

Phasefocus provides a range of products and services based on its proprietary Ptychographic Quantitative Phase Imaging technology to provide a wide range of analytical applications including label-free cell imaging and quantitative electron phase microscopy.

From Phase Focus Limited 4 May 2017

Heart failure patients have higher risk of death than people with common cancers

A study led by Keele University, in collaboration with the Universities of Aberdeen and Manchester, shows that men and women suffering from heart failure have a higher risk of death than people with most common types of cancer.

4 May 2017

Study finds worse survival rates for heart failure despite advances in treatment

A new analysis finds that, despite advances in care, men and women with a diagnosis of heart failure continue to have worse survival rates than patients with certain common cancers.

4 May 2017

Discovery could help design better drugs to fight against antibiotic-resistant superbugs

Antibiotic resistance is a growing global health threat. So much so that a 2014 study commissioned by the Prime Minister of the United Kingdom predicted that, if the problem is left unchecked, in less than 35 years more people will die from antibiotic-resistant superbugs than from cancer.

4 May 2017

Neuroscientists take new approach to addiction research with focus on quantifying craving in the brain

A new article in JAMA Psychiatry details the first step in revealing how craving works in the brain. Scientists at the Center for BrainHealth at The University of Texas at Dallas are the first to propose a systematic and quantitative model for drug addiction research.

4 May 2017

Researchers use mathematical modeling to find effective chemotherapy treatments for cancer patients

A team of Florida State University researchers is using mathematical modeling to find the best and most effective chemotherapy treatments for cancer patients.

4 May 2017

Lethal DNA re-replication may be used to attack cancer cells

DNA over-replication is a phenomenon that can have devastating consequences for proliferating cells. When parts of the genome are duplicated more than once, cells suffer from 'genomic instability' (alterations to the structure, composition and/or number of chromosomes), and this process gives rise to aberrant cells as those detected in many carcinomas.

4 May 2017

‘Helistroke service’ gets critical care to stroke victims faster than transporting patient to hospital

Flying a stroke specialist by helicopter to a nearby stroke patient for emergency care is feasible, saves money and, most importantly, gets critical care to patients faster than transporting the patient to a hospital first, according to a single-patient, proof-of-concept study by a Johns Hopkins Medicine research team.

3 May 2017

Day-to-day stressors can increase illegal drug use among people on probation or parole

A recent study finds that even small, day-to-day stressors can cause an increase in illegal drug use among people on probation or parole who have a history of substance use.

3 May 2017

Detailed images reveal how regulatory proteins affect function of brain receptors

Scientists at Columbia University have obtained the first detailed images of interactions between the AMPA receptor and molecules that regulate chemical signaling in the brain.

3 May 2017

Scientists grow and purify earliest lung progenitors from human stem cells

Human lungs, like all organs, begin their existence as clumps of undifferentiated stem cells. But in a matter of months, the cells get organized. They gather together, branch and bud, some forming airways and others alveoli, the delicate sacs where our bodies exchange oxygen for carbon dioxide.

3 May 2017

IU researchers develop new method to grow inner ear tissue from human stem cells

Researchers at Indiana University School of Medicine have successfully developed a method to grow inner ear tissue from human stem cells - PhDa finding that could lead to new platforms to model disease and new therapies for the treatment of hearing and balance disorders.

3 May 2017

Study provides evidence for antidepressant effects of ketamine

Better known as an anesthetic or as an illicit hallucinogenic drug, ketamine has also long been noted for alleviating depression. But ketamine has not been tested in a large clinical trial, and all evidence of its antidepressant effects has come from anecdotes and small studies of fewer than 100 patients.

3 May 2017

Researchers identify key player in initiation and progression of melanoma

Identification and functional validation of proteins involved in tumorigenesis are essential steps toward advancing cancer precision medicine. In The Journal of Clinical Investigation researchers from VIB, KU Leuven together with colleagues from INSERM now report the important role for FES in the initiation and progression of melanoma, a malignant type of skin cancer, that is notoriously quick to metastasize and that responds poorly to existing cancer treatments.

3 May 2017

Scientists map genetic changes that help drive aggressive brain tumor

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have mapped genetic changes that help drive an aggressive tumor as it develops in the brain – helping to lay the foundation for targeted treatment of the disease.

3 May 2017

Liver transplant patients who take new anti-rejection drug gain less weight, study finds

Researchers have discovered that a new anti-rejection drug that is gentler on the kidneys after liver transplant also reduces weight gain, which is common after surgery and can lead to serious complications for transplant patients.

3 May 2017

Scientists discover new cause of dangerous cardiac instabilities

Sudden cardiac death resulting from fibrillation – erratic heartbeat due to electrical instability – is one of the leading causes of death in the United States.

3 May 2017

Drugs News and Research

Research findings reveal new approach to prevent age-related obesity

Study finds no increase in muscle-related symptoms when patients are unaware of taking statin therapy

Synthetic biologists re-engineer yeast cells to manufacture antibiotic penicillin

New poster presented at ASCB shows power of Phasefocus’ Livecyte label-free cell analysis system

Heart failure patients have higher risk of death than people with common cancers

Study finds worse survival rates for heart failure despite advances in treatment

Discovery could help design better drugs to fight against antibiotic-resistant superbugs

Neuroscientists take new approach to addiction research with focus on quantifying craving in the brain

Researchers use mathematical modeling to find effective chemotherapy treatments for cancer patients

Lethal DNA re-replication may be used to attack cancer cells

‘Helistroke service’ gets critical care to stroke victims faster than transporting patient to hospital

Day-to-day stressors can increase illegal drug use among people on probation or parole

Detailed images reveal how regulatory proteins affect function of brain receptors

Scientists grow and purify earliest lung progenitors from human stem cells

IU researchers develop new method to grow inner ear tissue from human stem cells

Study provides evidence for antidepressant effects of ketamine

Researchers identify key player in initiation and progression of melanoma

Scientists map genetic changes that help drive aggressive brain tumor

Liver transplant patients who take new anti-rejection drug gain less weight, study finds

Scientists discover new cause of dangerous cardiac instabilities

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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