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Northwestern Medicine study reveals psychotherapy can alleviate genetically depressed rats

Genes are not destiny in determining whether an individual will suffer from depression, reports a new Northwestern Medicine study. Environment is a major factor, and nurture can override nature.

30 Mar 2016

New tool interprets whole-exome tumor sequencing data for better cancer therapies

A University of Colorado Cancer study published today in the Journal of the American Medical Informatics Association describes a new tool that interprets the raw data of whole exome tumor sequencing and then matches the cancer's unique genetics to FDA-approved targeted treatments.

30 Mar 2016

Gene plays vital role in controlling appetite for salt and risk of blood pressure

Scientists have shed light on why some people crave salty food, even when they know it can seriously damage their health.

30 Mar 2016

Study: 30% of hospital 'super-utilizers' are food insecure

More than half of patients with high hospitalization rates (at least 3 inpatient visits in a 12-month period) used food pantries or other community food resources, and 40% were worried that they would run out of food, according to the results of a study published in Population Health Management, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

30 Mar 2016

Multiple combination therapies could prevent malaria resistance

In order to preserve first-line drugs for treating malaria, multiple combination therapies should be deployed within a population to prevent resistance from developing, according to Maciej Boni from the Centre for Tropical Medicine and Global Health, University of Oxford, UK, and colleagues in a Policy Forum article published in this week's PLOS Medicine.

30 Mar 2016

Smoking drastically alters oral microbiome, study finds

Smoking drastically alters the oral microbiome, the mix of roughly 600 bacterial species that live in people's mouths. This is the finding of a study led by NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center to be published online March 25 in the ISME (International Society for Microbial Ecology) Journal.

30 Mar 2016

UGA and Sanofi Pasteur researchers develop new H1N1 influenza vaccine

Researchers at the University of Georgia and Sanofi Pasteur, the vaccines division of Sanofi, announced today the development of a vaccine that protects against multiple strains of both seasonal and pandemic H1N1 influenza in mouse models.

30 Mar 2016

TSRI study shows hollowed-out version of CPMV could be effective in human therapies

Viruses aren't always bad. In fact, scientists can harness the capabilities of some viruses for good—modifying the viruses to carry drug molecules, for example.

29 Mar 2016

Embryos with abnormalities in initial stages of pregnancy may grow into healthy babies

Abnormal cells in the early embryo are not necessarily a sign that a baby will be born with a birth defect such as Down's syndrome, suggests new research carried out in mice at the University of Cambridge. In a study published today in the journal Nature Communications, scientists show that abnormal cells are eliminated and replaced by healthy cells, repairing - and in many cases completely fixing - the embryo.

29 Mar 2016

Researchers use novel technology to sequence Y chromosome in malaria spreading mosquitoes

A team of researchers with the Fralin Life Science Institute at Virginia Tech, working with a large international consortium, has sequenced the Y chromosome--the genetic driver of sex-determination and male fertility-- in a family of malaria spreading mosquitoes.

29 Mar 2016

New approach allows noninvasive identification of tumor mutations in lung cancer patients

Researchers at the Stanford University School of Medicine have devised a way to significantly increase the sensitivity of a technique to identify and sequence DNA from cancer cells circulating in a person's blood.

29 Mar 2016

New TAU study pinpoints precise mechanism that regulates inheritance of epigenetic responses

According to epigenetics -- the study of inheritable changes in gene expression not directly coded in our DNA -- our life experiences may be passed on to our children and our children's children. Studies on survivors of traumatic events have suggested that exposure to stress may indeed have lasting effects on subsequent generations. But how exactly are these genetic "memories" passed on?

29 Mar 2016

Japanese scientists decode sugar molecule linked to muscular dystrophy

A group of Japanese scientists have succeeded in decoding a sugar molecule and clarifying a mechanism linked to muscular dystrophy. Their discovery has potential implications for muscular dystrophy treatment. The results of their research were published in the journal Cell Reports on February 25, 2016 EST.

29 Mar 2016

Scientists identify two enzymes that appear to play role in metabolism, inflammation

A team led by scientists at The Scripps Research Institute and the Salk Institute for Biological Studies has discovered two enzymes that appear to play a role in metabolism and inflammation—and might someday be targeted with drugs to treat type 2 diabetes and inflammatory disorders.

29 Mar 2016

UT Southwestern scientists discover mutation that causes X-linked reticulate pigmentary disorder

UT Southwestern Medical Center researchers have discovered a mutation that causes a rare systemic disorder known as X-linked reticulate pigmentary disorder (XLPDR) and, significantly, the unexpected cellular mechanism by which the mutation causes the disease.

29 Mar 2016

SLU scientist describes several tactics that can help cells overcome lesions

In a recent review paper published in Nature Structural & Molecular Biology, SLU scientist Alessandro Vindigni, Ph.D., describes the strategies cells use when their DNA faces replication stress, challenges that may derail a cell's ability to reproduce.

29 Mar 2016

Genetic News and Research

Northwestern Medicine study reveals psychotherapy can alleviate genetically depressed rats

New tool interprets whole-exome tumor sequencing data for better cancer therapies

Gene plays vital role in controlling appetite for salt and risk of blood pressure

Study: 30% of hospital 'super-utilizers' are food insecure

Multiple combination therapies could prevent malaria resistance

Smoking drastically alters oral microbiome, study finds

UGA and Sanofi Pasteur researchers develop new H1N1 influenza vaccine

TSRI study shows hollowed-out version of CPMV could be effective in human therapies

Embryos with abnormalities in initial stages of pregnancy may grow into healthy babies

Researchers use novel technology to sequence Y chromosome in malaria spreading mosquitoes

New approach allows noninvasive identification of tumor mutations in lung cancer patients

New TAU study pinpoints precise mechanism that regulates inheritance of epigenetic responses

Japanese scientists decode sugar molecule linked to muscular dystrophy

Scientists identify two enzymes that appear to play role in metabolism, inflammation

UT Southwestern scientists discover mutation that causes X-linked reticulate pigmentary disorder

SLU scientist describes several tactics that can help cells overcome lesions

Study reveals new hypothesis on evolution of hundreds of malaria species

Study identifies genetic differences in kidney tumors of African-Americans

Inactivation of protein-coding gene promotes liver tissue regeneration in mammals

Genetic syndrome may underlie some Parkinson's cases

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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