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Synthetic scaffold loaded with cancer-fighting T cells effectively shrinks solid tumors

Cellular therapy hasn't had much success in fighting solid tumors, partly because it's been difficult to deliver anti-cancer T cells to the tumors.

25 Apr 2017

New plant therapy developed at WPI cures patients with drug-resistant malaria

When the standard malaria medications failed to help 18 critically ill patients, the attending physician in a Congo clinic acted under the "compassionate use" doctrine and prescribed a not-yet-approved malaria therapy made only from the dried leaves of the Artemisia annua plant.

25 Apr 2017

Study shows how gut microbiota may play role in effectiveness of chemotherapy drugs

The bacteria residing in your digestive tract, or your gut microbiota, may play an important role in your ability to respond to chemotherapy drugs in the clinic, according to a new study by scientists at the University of Massachusetts Medical School.

25 Apr 2017

Scientists use stem cells to identify underlying cellular defects that cause Angelman syndrome

Researchers at UConn Health used stem cells derived from patients with Angelman syndrome to identify the underlying cellular defects that cause the rare neurogenetic disorder, an important step in the ongoing search for potential treatments for Angelman and a possible cure.

25 Apr 2017

New findings support use of integrative therapies for treating breast cancer patients

In newly updated clinical guidelines from the Society for Integrative Oncology, researchers at Columbia University's Mailman School of Public Health and the Herbert Irving Comprehensive Cancer Center with an interdisciplinary team of colleagues at MD Anderson Cancer Center, University of Michigan, Memorial Sloan Kettering Cancer Center, and other institutions in the U.S. and Canada, analyzed which integrative treatments are most effective and safe for patients with breast cancer.

24 Apr 2017

Penn State researchers receive NIH funding to explore malaria transmission in Southeast Asia

Researchers at Penn State have received more than $1 million in first-year funding from the National Institutes of Health to investigate malaria transmission in Southeast Asia with a goal of working toward the disease's elimination in the region.

24 Apr 2017

Intraoperative methadone offers promise to reduce need for pain medications during recovery

Patients undergoing spinal fusion surgery who are treated with methadone during the procedure require significantly less intravenous and oral opioids to manage postoperative pain, reports a new study published in the May issue of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists.

24 Apr 2017

Statins may provide favorable outcomes to patients with HBV- or HCV-related cirrhosis

Infection with hepatitis B virus (HBV) or hepatitis C virus (HCV) can lead to cirrhosis as well as liver cancer. A Hepatology study from Taiwan has found that statins may provide benefits to patients with HBV- or HCV-related cirrhosis.

24 Apr 2017

New model for toxicity risk assessment could reduce reliance on animal testing

Traditional toxicological investigations performed on animals (in vivo) are expensive, time-consuming and may cause animal suffering.

24 Apr 2017

Tiny silica 'cages' could help store and transport vaccines without refrigeration

Vaccines and antibodies could be transported and stored without refrigeration by capturing them in tiny silica 'cages', a discovery which could make getting vital medicines to remote or dangerous places much easier, cheaper and safer.

24 Apr 2017

$Women at highest genetic risk for fracture benefit most from hormone therapy, study finds$

Women at highest genetic risk for fracture benefit most from hormone therapy, study finds

Women at the highest genetic risk for fracture benefit the most from hormone therapy, according to a first-of-its-kind study led by researchers at the University at Buffalo.

24 Apr 2017

New test can quickly and accurately diagnose dangerous colistin-resistant bacteria

New research suggests it is possible to quickly and accurately diagnose some the most dangerous and drug-resistant types of bacterial infections, using equipment already owned by most hospitals.

24 Apr 2017

Testing for molecular markers in urine could reveal early signs of kidney transplant failure

Testing for molecular markers in the urine of kidney transplant patients could reveal whether the transplant is failing and why, according to research presented at the 27th European Congress of Clinical Microbiology and Infectious Diseases.

24 Apr 2017

Research findings may help doctors to better treat bloodstream infections with fewer side effects

Patients with bloodstream infections could avoid treatment with a combination of antimicrobial therapies if they are given the right drug as early as possible and if they are classified as at low risk of death.

24 Apr 2017

Antibiotic-resistant bacteria in patients’ urine or stools linked to increased risk of drug-resistant sepsis

People who have recently been found to have drug-resistant bacteria in their urine or stool samples have a greatly increased risk of developing a bloodstream infection that is also resistant to certain antibiotics, according to a study presented at the 27th European Congress of Clinical Microbiology and Infectious Diseases.

24 Apr 2017

Global Kidney Health Atlas highlights huge gaps in CKD care and prevention

Despite one in 10 people worldwide having chronic kidney disease, a new global report - The Global Kidney Health Atlas - presented at this week's World Congress of Nephrology in Mexico City and compiled by the International Society of Nephrology and kidney health experts worldwide and published in JAMA- highlights the huge gaps in kidney disease care and prevention in both developed and developing countries, with many countries not prioritising kidney health.

21 Apr 2017

Researchers awarded NIAID grant to develop new tools for eliminating drug-resistant malaria

The University of Maryland School of Medicine has been awarded a $9 million seven-year grant by the National Institute of Allergy and Infectious Diseases to develop new tools to help eliminate drug-resistant malaria in Southeast Asia and other regions where the disease is common.

21 Apr 2017

UC San Diego Amazonian Center to receive NIH funding for malaria research

The Amazonian Center of Excellence for Malaria Research, headed by Joseph Vinetz, MD, professor of medicine and tropical disease specialist at University of California San Diego School of Medicine, will receive up to approximately $8.3 million over seven years from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

21 Apr 2017

NIH announces 2017 ICEMR awards for 7 international malaria research centers

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, today announced approximately $9 million in first-year funding, subject to availability, for seven malaria research centers around the world.

21 Apr 2017

New technique can test effectiveness of treatments for breast cancer metastases in bone

A new laboratory technique developed by researchers at Baylor College of Medicine and other institutions can rapidly test the effectiveness of treatments for life-threatening breast cancer metastases in bone. The study appears in Nature Communications.

21 Apr 2017

Drugs News and Research

Synthetic scaffold loaded with cancer-fighting T cells effectively shrinks solid tumors

New plant therapy developed at WPI cures patients with drug-resistant malaria

Study shows how gut microbiota may play role in effectiveness of chemotherapy drugs

Scientists use stem cells to identify underlying cellular defects that cause Angelman syndrome

New findings support use of integrative therapies for treating breast cancer patients

Penn State researchers receive NIH funding to explore malaria transmission in Southeast Asia

Intraoperative methadone offers promise to reduce need for pain medications during recovery

Statins may provide favorable outcomes to patients with HBV- or HCV-related cirrhosis

New model for toxicity risk assessment could reduce reliance on animal testing

Tiny silica 'cages' could help store and transport vaccines without refrigeration

Women at highest genetic risk for fracture benefit most from hormone therapy, study finds

New test can quickly and accurately diagnose dangerous colistin-resistant bacteria

Testing for molecular markers in urine could reveal early signs of kidney transplant failure

Research findings may help doctors to better treat bloodstream infections with fewer side effects

Antibiotic-resistant bacteria in patients’ urine or stools linked to increased risk of drug-resistant sepsis

Global Kidney Health Atlas highlights huge gaps in CKD care and prevention

Researchers awarded NIAID grant to develop new tools for eliminating drug-resistant malaria

UC San Diego Amazonian Center to receive NIH funding for malaria research

NIH announces 2017 ICEMR awards for 7 international malaria research centers

New technique can test effectiveness of treatments for breast cancer metastases in bone

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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