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HCM mutation prevents the heart from increasing pumping force, study shows

Researchers from Washington State University have discovered how a genetic mutation linked to hypertrophic cardiomyopathy (HCM) disrupts the heart's normal function.

21 May 2018

Researchers identify protein essential for eye lens development and clear vision

If you want to take clear photographs, you don't use sandpaper to clear a smudge from your camera's lens. Similarly, if you want to see clearly, the lens of your eye has to be free of obstruction.

21 May 2018

Flow of cerebrospinal fluid found to be key signal for neural stem cell renewal

Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory.

21 May 2018

New blood test could help avoid more than 40% of prostate biopsies, study finds

A multi-center study that validates the clinical performance of IsoPSA - a new blood test that has proven to be more accurate in predicting overall risk of prostate cancer than standard prostate-specific antigen - will be presented during a special press conference at the 13th Annual Meeting of the American Urological Association on May 18 in San Francisco.

18 May 2018

Study offers novel solution to suppress metastatic spread of deadly breast cancer

USC researchers have pinpointed a remedy to thwart a protein that helps the metastatic spread of breast cancer, a leading cause of death for women. The findings appear today in Nature Communications.

18 May 2018

Scientists identify new potential target to combat acute myeloid leukemia

AML is not a single disease. It is a group of leukemias that develop in the bone marrow from progenitors of specialized blood cells, the so-called myeloid cells. Rapidly growing and dividing, these aberrant cells crowd the bone marrow and bloodstream, which can be fatal within weeks or months if the disease is left untreated.

18 May 2018

Researchers uncover unusual form of cross-talk between proteins that affect gene expression

Turning genes on and off is an intricate process involving communication between many different types of proteins that interact with DNA.

18 May 2018

Study: Single surface protein can amplify multiple key pathways in acute myeloid leukemia

Researchers from the Albert Einstein College of Medicine in New York have discovered that a signaling protein elevated in patients with acute myeloid leukemia plays a much wider role in the disease than previously thought.

18 May 2018

Study: Psoriasis patients taking Humira show no change in aortic inflammation

An antibody used to treat the skin disease psoriasis and other chronic autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease has no effect on aortic inflammation – a key marker of future risk of major cardiovascular events – unlike other antibodies that target different aspects of the immune system.

18 May 2018

Study finds body temperature as major barrier to potential dengue, Zika vaccine

A major route toward creating effective vaccines against dengue virus and Zika involves the E protein that covers the surface of each viral particle.

18 May 2018

New study shows link between blood type and severity of diarrhea caused by E. coli

A new study shows that a kind of E. coli most associated with "travelers' diarrhea" and children in underdeveloped areas of the world causes more severe disease in people with blood type A.

18 May 2018

Researchers report new signaling exchange that mediates normal mammary gland development

The human body develops most tissue types during fetal development, in a mother's uterus. Yet one only tissue develops after birth: the mammary gland.

18 May 2018

Study: Macrophages play key role in maintaining stem cell niche of mammary gland

A new study finds that one of the toughest characters in the immune system, the macrophage, has a nurturing side, at least when it comes to guarding the developing breast.

18 May 2018

Microglia may play key role in slowing progression of prion diseases, research suggests

Prion diseases are slow degenerative brain diseases that occur in people and various other mammals. No vaccines or treatments are available, and these diseases are almost always fatal. Scientists have found little evidence of a protective immune response to prion infections.

17 May 2018

New blood test shows promise for early detection of pancreatic cancer

Pancreatic cancer is expected to become the second deadliest cancer in the United States by 2030. It is tough to cure because it is usually not discovered until it has reached an advanced stage. But a new diagnostic test developed by researchers at UC San Diego shows promise for detecting the disease earlier.

17 May 2018

Study provides insights into how immune cells kill bacteria with acid

The first line of immune defense against invading pathogens like bacteria are macrophages, immune cells that engulf every foreign object that crosses their way. After enclosing it in intracellular membrane vesicles, a process called phagocytosis, macrophages kill their prey with acid.

17 May 2018

Old drug offers new hope for treatment of MND

An international study led by biochemists at the University of Liverpool has shown that the drug-molecule ebselen can correct many of the toxic characteristics of a protein that causes some cases of hereditary motor neurone disease (MND).

17 May 2018

Scientists discover how unusually long strands of RNA help colon cancer cells avoid death

Researchers from Case Western Reserve University School of Medicine have discovered how unusually long strands of RNA help colon cancer cells avoid death, allowing unregulated growth.

17 May 2018

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

Obsidian Therapeutics, Inc., a biotechnology company dedicated to the development of next-generation cell and gene therapies with pharmacologic operating systems, today announced that the company presented preclinical data on its regulated IL12 and IL15 programs at the Annual Meeting of the American Society of Gene and Cell Therapy in Chicago, IL.

17 May 2018

New study reveals the extent of brain damage due to elevated homocysteine

The amino acid homocysteine occurs naturally in the human body, generated as a byproduct of methionine metabolism.

17 May 2018

Protein C News and Research

HCM mutation prevents the heart from increasing pumping force, study shows

Researchers identify protein essential for eye lens development and clear vision

Flow of cerebrospinal fluid found to be key signal for neural stem cell renewal

New blood test could help avoid more than 40% of prostate biopsies, study finds

Study offers novel solution to suppress metastatic spread of deadly breast cancer

Scientists identify new potential target to combat acute myeloid leukemia

Researchers uncover unusual form of cross-talk between proteins that affect gene expression

Study: Single surface protein can amplify multiple key pathways in acute myeloid leukemia

Study: Psoriasis patients taking Humira show no change in aortic inflammation

Study finds body temperature as major barrier to potential dengue, Zika vaccine

New study shows link between blood type and severity of diarrhea caused by E. coli

Researchers report new signaling exchange that mediates normal mammary gland development

Study: Macrophages play key role in maintaining stem cell niche of mammary gland

Microglia may play key role in slowing progression of prion diseases, research suggests

New blood test shows promise for early detection of pancreatic cancer

Study provides insights into how immune cells kill bacteria with acid

Old drug offers new hope for treatment of MND

Scientists discover how unusually long strands of RNA help colon cancer cells avoid death

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

New study reveals the extent of brain damage due to elevated homocysteine

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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