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Study shows possibility to reduce antipsychotic use among nursing home residents with dementia

The use of antipsychotic medication in nearly 100 Massachusetts nursing homes was significantly reduced when staff was trained to recognize challenging behaviors of cognitively impaired residents as communication of their unmet needs, according to a new study led by Jennifer Tjia, MD, MSCE, associate professor of quantitative health sciences.

17 Apr 2017

Electroacupuncture may lead to better blood sugar regulation in obese and overweight women

For women who are overweight or obese and are unable to exercise, new research appearing online in The FASEB Journal suggests combining acupuncture with an electrical current may help.

17 Apr 2017

Vanderbilt geneticists find new way to tap plant pharmacopeia to produce improved therapeutics

Cocaine, nicotine, capsaicin. These are just three familiar examples of the hundreds of thousands of small molecules (also called specialized or secondary metabolites) that plants use as chemical ammunition to protect themselves from predation.

17 Apr 2017

TSRI scientists develop easy method for synthesizing compounds with potential to treat lung disorders

Chemists at The Scripps Research Institute have developed a broad and strikingly easy method for synthesizing a class of molecules that have demonstrated value as pharmaceuticals.

17 Apr 2017

Thyroid cancer patients with bone metastases have worse survival, study finds

When cancer metastases, bone unwittingly offers a friendly place for tumor cell growth--only to have its hospitality betrayed by pathologic fractures, spinal cord compression, the need for bone surgery or irradiation, and an increased risk of death.

17 Apr 2017

Chagas disease confirmed as 'silent killer' in first large-scale US survey

A study of almost 5,000 Latin American-born residents of Los Angeles County found that 1.24% tested positive for Chagas disease, a parasitic infection that can cause life-threatening heart damage if not treated early. Chagas disease is one of the leading causes of heart failure in Latin America.

14 Apr 2017

Common drugs, uncommon risks? Higher rate of serious problems after short-term steroid use

Millions of times a year, Americans get prescriptions for a week's worth of steroid pills, hoping to ease a backache or quell a nagging cough or allergy symptoms. But a new study suggests that they and their doctors might want to pay a bit more attention to the potential side effects of this medication.

14 Apr 2017

Injection drug use linked to increase in immune activation, says researcher

The use of heroin and other illicit drugs has been shown to trigger a response from the body's immune system.

13 Apr 2017

Study finds depression and SUD to be strongest risk factors for prescription opioid overdose

Individuals suffering from a substance use disorder (SUD) or depression are among those at highest risk for a serious prescription opioid overdose, according to a study published in Pain Medicine.

13 Apr 2017

Researchers uncover global regulator that 'switches on' silent biosynthetic gene clusters

Bacteria have supplied some of today's most indispensable anti-cancer and anti-bacterial drugs. Yet these compounds comprise only a fraction of their possible offerings. Now, researchers have found a way to unleash their full potential as natural product dispensers.

13 Apr 2017

Novel non-invasive technique can deliver drugs to the brain via nanoparticles

Delivering life-saving drugs directly to the brain in a safe and effective way is a challenge for medical providers.

12 Apr 2017

Gut microbes cause age-associated inflammation and premature death, mice study shows

Gut microbes cause age-associated inflammation and premature death in mice, McMaster University researchers have found. The study could lead to new strategies to improve intestinal health and immune function in older adults.

12 Apr 2017

NIH study provides unprecedented detail on host response to Ebola virus disease

Analysis of daily gene activation in a patient with severe Ebola virus disease cared for at the National Institutes of Health (NIH) in 2015 found changes in antiviral and immune response genes that pinpointed key transition points in the response to infection.

12 Apr 2017

Developmental Split-Brain syndrome discovery

Our group describes a new entity, which we refer to as “Developmental Split-Brain syndrome” which we discovered affected four individuals from three unrelated families. All affected individuals showed disruption of communicating tracts between the right and left side of the brain which meant that there is lack of coordination and communication between the two sides of the brain.

12 Apr 2017

'Love hormone' could hold key to treating drug addicts, say experts

Experts say oxytocin, a key hormone made naturally by the brain, could hold the key to treating drug addicts and help them avoid relapse.

12 Apr 2017

Transmembrane protein complexes shed light on antibiotic resistance in bacteria

An international team including researchers from MIPT’s Laboratory for Advanced Studies of Membrane Proteins have proposed an explanation of the way bacteria process external signals.

12 Apr 2017

Point/Counterpoint: Experts debate how to control exploding opioid epidemic

Two experts with opposing views squared off on the hotly debated topic of how best to control the exploding opioid epidemic in the U.S.- with increasing regulation of physician prescribing practices or by better educating patients and doctors.

12 Apr 2017

Researchers explore patient adherence, tolerability to class of Alzheimer's drugs

Researchers from the Indiana University Center for Aging Research and the Regenstrief Institute have performed the first study conducted in the United States under real-world conditions comparing patient adherence and tolerability to a class of drugs known as cholinesterase inhibitors.

11 Apr 2017

PID1 gene increases killing effect of chemotherapy drugs on brain tumor cells

Investigators at The Saban Research Institute of Children's Hospital Los Angeles have found that the gene PID1 enhances killing of medulloblastoma and glioblastoma cells.

11 Apr 2017

TSRI scientists find new way to make cell population resistant to HIV

Scientists at The Scripps Research Institute have found a way to tether HIV-fighting antibodies to immune cells, creating a cell population resistant to the virus.

11 Apr 2017

Drugs News and Research

Study shows possibility to reduce antipsychotic use among nursing home residents with dementia

Electroacupuncture may lead to better blood sugar regulation in obese and overweight women

Vanderbilt geneticists find new way to tap plant pharmacopeia to produce improved therapeutics

TSRI scientists develop easy method for synthesizing compounds with potential to treat lung disorders

Thyroid cancer patients with bone metastases have worse survival, study finds

Chagas disease confirmed as 'silent killer' in first large-scale US survey

Common drugs, uncommon risks? Higher rate of serious problems after short-term steroid use

Injection drug use linked to increase in immune activation, says researcher

Study finds depression and SUD to be strongest risk factors for prescription opioid overdose

Researchers uncover global regulator that 'switches on' silent biosynthetic gene clusters

Novel non-invasive technique can deliver drugs to the brain via nanoparticles

Gut microbes cause age-associated inflammation and premature death, mice study shows

NIH study provides unprecedented detail on host response to Ebola virus disease

Developmental Split-Brain syndrome discovery

'Love hormone' could hold key to treating drug addicts, say experts

Transmembrane protein complexes shed light on antibiotic resistance in bacteria

Point/Counterpoint: Experts debate how to control exploding opioid epidemic

Researchers explore patient adherence, tolerability to class of Alzheimer's drugs

PID1 gene increases killing effect of chemotherapy drugs on brain tumor cells

TSRI scientists find new way to make cell population resistant to HIV

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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