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Imperial College London researchers discover new inherited form of obesity, type 2 diabetes

Scientists have discovered a new inherited form of obesity and type 2 diabetes in humans. A large number of genes are involved in regulating body weight, and there are now over 30 genes known in which people with harmful changes in DNA sequence become extremely overweight. Similarly, there are a number of genes that can, when altered, cause type 2 diabetes. These conditions are inherited through families in exactly the same way as disorders such as cystic fibrosis or Huntington's disease.

30 Jun 2015

New study sheds light on the effects of marijuana on weight gain in young adults

While cannabis alters the functions of neurobiological circuits controlling appetite, its effect on weight gain is complex since several factors appear to be involved, says Didier Jutras-Aswad, University of Montreal professor and researcher at the CHUM Research Centre. "It is known - and often reported by users - that cannabis causes temporary increase in appetite.

30 Jun 2015

Texas Biomed, Take Off Pounds Sensibly establish new TOPS Nutrition and Obesity Research Center

Texas Biomedical Research Institute and Wisconsin-based non-profit Take Off Pounds Sensibly are establishing the new TOPS® Nutrition and Obesity Research Center with the goal of conducting research into the causes, health risks and treatment of human obesity. Studies at the Center will focus on the role of genetic predisposition to metabolic changes, nutritional preferences, appetite regulation, food intake and choice and incidence of obesity-related illnesses.

27 Jun 2015

QUT researcher reveals how compulsive snacking can be a major cause of weight gain

A QUT researcher has had an article on how compulsive snacking is a major cause of weight gain published in the international journal Eating Behaviors.

26 Jun 2015

UC Riverside researchers explore effects of early-life exercise

More than one in three adults in the United States is considered to be obese. What impact can exercise done early in life have on the propensity for exercising during the adult years? A team of researchers at the University of California, Riverside did experiments on mice in the lab to find out. Specifically, they evaluated the effects of early exercise on adult physical activity, body mass, food consumption and circulating leptin levels.

25 Jun 2015

Sugar-gobbling enzyme helps restore normal function in heart muscles of diabetic rats

Working with heart muscle cells from diabetic rats, scientists at Johns Hopkins have located what they say is the epicenter of mischief wreaked by too much blood sugar and used a sugar-gobbling enzyme to restore normal function in the glucose-damaged cells of animal heart muscles.

25 Jun 2015

TSRI scientists devise powerful set of chemical methods to explore protein biology

Scientists at The Scripps Research Institute (TSRI) have devised a powerful set of chemical methods for exploring the biology of proteins.

22 Jun 2015

New study launched in Liberia to better understand health consequences of Ebola virus disease

The Liberia-U.S. clinical research partnership known as PREVAIL has launched a study of people in Liberia who have survived Ebola virus disease (EVD) within the past two years. The study investigators hope to better understand the long-term health consequences of EVD, determine if survivors develop immunity that will protect them from future Ebola infection, and assess whether previously EVD-infected individuals can transmit infection to close contacts and sexual partners.

18 Jun 2015

Rapamycin drug reduces obesity, preserves lean body mass in older rats

Aging can cause many changes to the body, including obesity and a loss of lean mass. Now, a group of University of Florida Health researchers has discovered that an existing drug reduces body fat and appetite in older rats, which has intriguing implications for aging humans.

17 Jun 2015

Protiviti's 'i on Hunger campaign' reaches one million meals goal

According to the World Food Programme, 805 million people in the world do not have enough food to lead a healthy active life, and poor nutrition causes nearly half (45 percent) of deaths in children under five years old – that's 3.1 million children each year. In the fall of 2014, global consulting firm Protiviti launched its year-long i on Hunger initiative as part of the fight to help end world hunger.

17 Jun 2015

Study reveals new information about role of abdominal fat in teens with CAH

Researchers at Children's Hospital Los Angeles have demonstrated that adolescents and young adults with congenital adrenal hyperplasia (CAH) have significantly increased amounts of abdominal fat tissue, placing them at greater risk for harmful conditions linked to obesity, including cardiovascular disease (CVD).

11 Jun 2015

Treating obesity with GLP-1 hormone helps prevent loss of bone mass associated with weight loss

Using the intestinal hormone GLP-1 in obesity treatment prevents the loss of bone mass otherwise frequently associated with major weight loss. This is the finding of a new study from the University of Copenhagen, Hvidovre and Glostrup Hospital. According to the researchers behind the study, the results may have a significant bearing on future obesity treatment.

11 Jun 2015

Study shows how GLP-1 receptor agonists modify the brain's response to food

Gut hormone-based medications used to treat diabetes, such as GLP-1 receptor agonists, have also been shown to reduce body weight. Researchers have been working to understand how. This study, presented today at the American Diabetes Association's 75th Scientific Sessions, sheds light on how GLP-1 receptor agonists alter the brain's response to food, possibly reducing cravings and increasing satisfaction while eating.

9 Jun 2015

Once-weekly Trulicity 0.75 mg shows promising results in Japanese patients with type 2 diabetes

Results from a new study of Japanese patients with type 2 diabetes showed once-weekly Trulicity 0.75 mg provided greater hemoglobin A1c (A1C) reduction compared to once-daily Victoza 0.9 mg after 52 weeks of treatment. Eli Lilly and Company will present these data at the 75th American Diabetes Association Scientific Sessions in Boston.

7 Jun 2015

Food labels effective in helping people make healthier food choices, shows study

A Cornell study of food labels in dining halls shows that when people know the calories and fat content in foods, they lean toward healthier fare.

5 Jun 2015

Rhythm announces initiation of two setmelanotide Phase 2 trials for treatment of PWS, POMC-null obesity

Rhythm announced today the initiation of two Phase 2 clinical trials focused on evaluating the safety and effectiveness of setmelanotide (RM-493), the company's novel melanocortin 4 receptor (MC4R) agonist, for the treatment of Prader-Willi Syndrome (PWS) and POMC-null obesity.

4 Jun 2015

New FRAC report shows more low-income children receive summer meals

More low-income children are eating summer meals, according to a new report released today by the Food Research and Action Center which showed more than 3.2 million children participated in the Summer Nutrition Programs in July 2014. This represents a seven percent increase over the previous year, and demonstrates what can be done when the federal government, states, and communities make summer food a priority.

2 Jun 2015

Enzalutamide Phase 2 study for AR positive triple-negative breast cancer meets primary endpoint

Astellas Pharma Inc. announced that data from a Phase 2 study evaluating the investigational use of enzalutamide as a single agent for the treatment of advanced androgen receptor (AR) positive, triple-negative breast cancer (TNBC) were presented during an oral abstracts session at the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

2 Jun 2015

Lenvatinib-everolimus combination extends PFS in patients with mRCC versus everolimus alone

Eisai Inc. announced today results from an investigational Phase 2 trial which showed that lenvatinib, when used in combination with everolimus, significantly extended progression-free survival (PFS) in patients with metastatic renal cell carcinoma (mRCC) versus everolimus alone.

1 Jun 2015

People with common form of lung cancer can benefit from nivolumab drug

In a head-to-head clinical trial comparing standard chemotherapy with the immunotherapy drug nivolumab, researchers found that people with squamous-non-small cell lung cancer who received nivolumab lived, on average, 3.2 months longer than those receiving chemotherapy.

1 Jun 2015

Appetite News and Research

Imperial College London researchers discover new inherited form of obesity, type 2 diabetes

New study sheds light on the effects of marijuana on weight gain in young adults

Texas Biomed, Take Off Pounds Sensibly establish new TOPS Nutrition and Obesity Research Center

QUT researcher reveals how compulsive snacking can be a major cause of weight gain

UC Riverside researchers explore effects of early-life exercise

Sugar-gobbling enzyme helps restore normal function in heart muscles of diabetic rats

TSRI scientists devise powerful set of chemical methods to explore protein biology

New study launched in Liberia to better understand health consequences of Ebola virus disease

Rapamycin drug reduces obesity, preserves lean body mass in older rats

Protiviti's 'i on Hunger campaign' reaches one million meals goal

Study reveals new information about role of abdominal fat in teens with CAH

Treating obesity with GLP-1 hormone helps prevent loss of bone mass associated with weight loss

Study shows how GLP-1 receptor agonists modify the brain's response to food

Once-weekly Trulicity 0.75 mg shows promising results in Japanese patients with type 2 diabetes

Food labels effective in helping people make healthier food choices, shows study

Rhythm announces initiation of two setmelanotide Phase 2 trials for treatment of PWS, POMC-null obesity

New FRAC report shows more low-income children receive summer meals

Enzalutamide Phase 2 study for AR positive triple-negative breast cancer meets primary endpoint

Lenvatinib-everolimus combination extends PFS in patients with mRCC versus everolimus alone

People with common form of lung cancer can benefit from nivolumab drug

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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