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Study reveals how mTORC1-driven changes in crowding could influence major diseases

Among the most studied protein machines in history, mTORC1 has long been known to sense whether a cell has enough energy to build the proteins it needs to multiply as part of growth.

22 Jun 2018

Study reveals new target to halt tumor growth

Researchers at the University of Wisconsin-Madison have discovered that a protein called Munc13-4 helps cancer cells secrete large numbers of exosomes - tiny, membrane-bound packages containing proteins and RNAs that stimulate tumor progression.

21 Jun 2018

Inhibiting epigenetic proteins with drugs could prevent development of breast cancer

Researchers at the Princess Margaret Cancer Centre in Toronto have discovered that epigenetic proteins promote the proliferation of mammary gland stem cells in response to the sex hormone progesterone.

19 Jun 2018

Cells form cage-like structures that trap viruses, find scientists

Scientists have shown that cells can form cage-like structures around viruses to trap them and prevent them from spreading to nearby cells.

19 Jun 2018

Scientists develop novel computational framework to support personalized cancer treatment

Researchers at Columbia University Irving Medical Center have developed a highly innovative computational framework that can support personalized cancer treatment by matching individual tumors with the drugs or drug combinations that are most likely to kill them.

19 Jun 2018

Scientists point to potentially promising treatment target for deadly brain cancers

Scientists report finding a potentially promising treatment target for aggressive and deadly high-grade brain cancers like glioblastoma. But they also say the current lack of a drug that hits the molecular target keeps it from being advanced for testing as a therapeutic strategy for patients with few treatment options.

18 Jun 2018

WVU researcher aims to produce updated whooping cough vaccine

Before the whooping-cough vaccine came into widespread use in the 1940s, about 9,000 American children died from the infection each year. Today, thanks to the vaccine's efficacy, reported cases of whooping cough have dramatically declined and fatalities have dropped to up to 20 children each year.

18 Jun 2018

Engineers create first 3D computer model to show breast duct development

Working with hundreds of time-lapse videos of mouse tissue, a team of biologists joined up with civil engineers to create what is believed to be the first 3D computer model to show precisely how the tiny tubes that funnel milk through the breasts of mammals form.

14 Jun 2018

New studies on fat cell filling, history of biochemistry, and ketogenic diet

There's more than one type of fat cell. Besides the white fat that stores triglycerides in lipid droplets in preparation for lean times later, mammals also have heat-generating brown fat, which acts more like a radiator than a storage closet.

14 Jun 2018

Scientists discover unique feature in the 'antennae' of light-sensing neurons

Scientists at Baylor College of Medicine and Radboud University Medical Center in the Netherlands have discovered that the antennae-like structures on light-sensing neurons, called photoreceptors, have a unique feature not observed in the 'antennae' or cilia of other types of cells.

14 Jun 2018

Researchers develop ground-breaking approach for treatment of pneumonia

A chance conversation between researchers at Queen's University Belfast led to their combined expertise in developing a ground-breaking approach for the treatment of pneumonia.

13 Jun 2018

Scientists find role of schizophrenia gene in brain development

A USC research team identified 150 proteins affecting cell activity and brain development that contribute to mental disorders, including schizophrenia, bipolar condition and depression.

8 Jun 2018

Overload of zinc in muscles leads to cachexia in cancer patients

It's estimated that nearly one-third of all cancer deaths are caused not by the cancer itself but by cachexia - a debilitating muscle-wasting syndrome that affects an estimated 80 percent of advanced cancer patients. Cachexia is linked to reduced tolerance for cancer therapy, poor quality of life, and accelerated death, but there are no effective treatments and its cause is still largely unknown.

6 Jun 2018

Scientists shed light on key aspect of healthy cell division

Scientists have shed light on a key aspect of healthy cell division, helping build a clearer picture of the complex mechanisms involved.

5 Jun 2018

International respiratory group calls for immediate ban on flavorings and marketing of e-cigarettes

In a statement published in the European Respiratory Journal, a coalition of respiratory doctors and scientists from six continents have warned of the dangers posed to children and adolescents by electronic cigarettes.

1 Jun 2018

Cancer cells can use lipid molecules as fuel for growth, shows study

Cancer cells can when the blood supply is low use lipid molecules as fuel instead of blood glucose. This has been shown in animal tumor models by researchers at Karolinska Institutet in Sweden in a study published in Cell Metabolism.

1 Jun 2018

Cancer cells co-opt pain-sensing 'neural channel' to increase tolerance against oxidative stress

Anyone who's taken a bite of a sandwich with too much spicy mustard or a piece of sushi with too much wasabi can attest to the tear-inducing sensation these condiments can cause. These loud warnings to the nervous system of exposure to potentially harmful chemicals are triggered by TRPA1, a calcium channel protein sometimes referred to as the "wasabi receptor."

25 May 2018

New research will use mathematics to solve mysteries in cell biology

A new interdisciplinary research and education center at the University of California, Irvine will apply the power of mathematics to some of the more vexing mysteries in cell biology.

25 May 2018

Mapping the Genes Responsible for Pluripotency

Dr. Atilgan Yilmaz and his team have developed a method by which they can produce haploid human embryonic stem cells from oocytes. They combined this technique with CRISPR-Cas9 to generate an atlas of the genome, containing the functions of over 18,000 genes.

23 May 2018