Cell Nucleus News and Research

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Genetic mutations involved in IGF-I signaling pathway influence life span

Mutations in genes governing an important cell-signaling pathway influence human longevity, scientists at the Albert Einstein College of Medicine of Yeshiva University have found.

6 Mar 2008

Tiny RNA molecule found to help create skin's protective barrier

Every minute, 30,000 of our outermost skin cells die so that we can live. When they do, new cells migrate from the inner layer of the skin to the surface of it, where they form a tough protective barrier.

4 Mar 2008

Nanotechnology advances brain cancer detection and therapy

Brain cancer is one of the most aggressive and lethal of malignancies, made even more difficult to treat by the fact that most anticancer drugs have a hard time even getting to the tumors.

3 Mar 2008

Short RNA strand helps exposed skin cells protect body from bacteria, dehydration and even cancer

Every minute, 30,000 of our outermost skin cells die so that we can live.

3 Mar 2008

Novel link between excessive nutrient levels and insulin resistance

For quite some time now, scientists suspected the so-called hexosamine pathway - a small side business of the main sugar processing enterprise inside a cell - to be involved in the development of insulin resistance.

22 Feb 2008

Link between excessive food intake and insulin resistance

22 Feb 2008

Curcumin reduces heart enlargement and may prevent heart failure

Eating curcumin, a natural ingredient in the spice turmeric, may dramatically reduce the chance of developing heart failure, researchers at the Peter Munk Cardiac Centre of the Toronto General Hospital have discovered.

22 Feb 2008

Genetic tags reveal secrets of memories' staying power in mice

A better understanding of how memory works is emerging from a newfound ability to link a learning experience in a mouse to consequent changes in the inner workings of its neurons.

21 Feb 2008

Discovery of gene expression pathway that influences process of oxidative stress

The same chemical reaction that causes iron to rust plays a similarly corrosive role in our bodies.

21 Feb 2008

Scientists shed light on long-distance signaling in developing neurons

A longstanding puzzle in neurodevelopment may have yielded up a key secret.

20 Feb 2008

New key finding in neurodevelopment

A longstanding puzzle in neurodevelopment may have yielded up a key secret. A team led by scientists at Weill Cornell Medical College says they have determined how events at the very tips of the developing neuron's long, skinny axon affect gene transcription back in the cell's distant nucleus.

20 Feb 2008

Protein found in the saliva of deer ticks prevents the HIV-1 virus from attaching to the surface of T cells

The HIV-1 virus cripples the human immune system by targeting white blood cells called T cells that form the body's first line of defense in fighting infections.

17 Feb 2008

Oncoproteins double-team and destroy vital tumor-suppressor

Two previously unconnected cancer-promoting proteins team up to ambush a critical tumor suppressor by evicting it from the cell's nucleus and then marking it for death by a protein-shredding mechanism, a team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Feb. 10 issue of Nature Cell Biology.

17 Feb 2008