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Study finds fewer cases of MIS-C during omicron wave of the pandemic than delta

A new University at Buffalo study conducted at John R. Oishei Children's Hospital is one of the first to reveal that there were fewer cases of multi-system inflammatory syndrome in children (MIS-C) during the omicron wave of the pandemic than the delta wave.

19 Jan 2023

Exploring the infectivity, transmissibility, and immunological resistance characteristics of SARS-CoV-2 Omicron XBB.1.5 strain

Researchers performed an epidemic dynamic analysis to assess the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC)’s sub-VOC XBB.1.5 characteristics.

19 Jan 2023

Long-term, COVID-19-related smell loss could be treated using injections of platelet-rich plasma

Early in the pandemic, when people with COVID-19 began reporting that they lost their sense of smell, Zara Patel, MD, figured as much. A professor of otolaryngology at Stanford Medicine, Patel has, for years, studied loss of smell as a symptom of viral infections.

19 Jan 2023

Researchers find that study results converge on a consistent relationship between antibody levels and protection from COVID-19

Researchers described the factors associated with protection, protection thresholds, and immunobridging in COVID-19 patients.

19 Jan 2023

How is long COVID diagnosed in adults?

In a recent study, researchers enlisted important points concerning post-coronavirus disease 2019 (COVID-19) or long COVID diagnosis among adults.

19 Jan 2023

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

Researchers explored the relationship between the development of goblet inflammatory cells and the age-related pathophysiology of SARS-CoV-2.

19 Jan 2023

New study highlights the under-reporting of COVID-19 deaths in the US

A study conducted by US-based scientists highlights that a considerable percentage of coronavirus disease 2019 (COVID-19)-related deaths remains unreported in different counties across the United States.

19 Jan 2023

New research reveals that childhood omicron infections have been under-reported in Canadian schools

A recent study from the east coast of Canada evaluated the extent of under-reporting among school children from elementary to high schools.

19 Jan 2023

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Researchers explored how mutations in emergent SARS-CoV-2 variants affect viral function, human immunity, and recognition by therapeutic antibodies.

19 Jan 2023

Diagnosis and treatment of people with long COVID

About 1.4 million people in Canada have been affected by long COVID after infection, or suspected infection, with SARS-CoV-2. A new trio of practice articles in CMAJ (Canadian Medical Association Journal) aims to help clinicians diagnose, assess and treat people with long COVID.

18 Jan 2023

Does COVID-19 cause adverse pregnancy and neonatal outcomes?

Early in the coronavirus disease 2019 (COVID-19) pandemic, pregnant women were thought to be at unusually high risk from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared to the general population or non-pregnant women. However, later studies failed to agree on the extent and nature of the danger posed by the infection.

18 Jan 2023

T-cell immunity and antibody responses against SARS-CoV-2 among individuals registered in the Bangkok home health care service

Researchers performed an observational study among COVID-19 patients and their close contacts registered with the Bangkok home health care services in Thailand.

18 Jan 2023

Epitope mapping reveals the humoral responses against the main SARS-CoV-2 structural proteins in infected patients from Africa

Researchers performed immunoglobulin (Ig)M and IgG epitope mapping against 487 SARS-CoV-2 peptides.

18 Jan 2023

Study sheds new light on how the B cell academy mounts a diverse immune response

Cells jostling for a spot in a germinal center face a cutthroat admissions process. Formed after exposure to a pathogen or vaccine, germinal centers act as a kind of immune system training academy, helping B cells refine their response to the threat.

18 Jan 2023

Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variants

A new study describes that tight transmission bottlenecks restrict the evolution of SARS-CoV-2 in the transmission chain. SARS-CoV-2 is the causative pathogen of the COVID-19 pandemic.

18 Jan 2023

What does the future of clinical trials and evidence-based medicine look like?

In a recent perspective published in Nature Medicine, the researcher shared his vision and future perspectives for the domains of clinical research and evidence-based therapeutics.

18 Jan 2023

The efficacy of low-dose fluvoxamine compared with placebo for treating mild to moderate COVID-19 in the US

Researchers evaluated the efficacy of low-dosage fluvoxamine (50 mg two times a day) over 10 days in the management of mild and moderate-SARS-CoV-2 infections in the US.

18 Jan 2023

Upregulation of Robo4 expression reduces mortality from severe infection

The researchers screened a library of drugs using a mouse endothelial cell line to identify pathways that are involved in the regulation of Robo4 and found that two competitive SMAD signaling pathways appear to regulate Robo4 expression.

18 Jan 2023

Exploring a novel amplicon-based mpox virus sequencing strategy

Researchers described the development of a sequencing strategy based on amplicons for mpox detection.

18 Jan 2023

The "Great Escape" by SARS-CoV-2 XBB.1

In a recent article published in the Lancet Microbe, researchers in the Netherlands and the United Kingdom quantified the antigenic diversity of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subvariants, BQ.1.1, BM.1.1.1, and XBB.1, all derivatives of the variant of concern (VOC) Omicron, which emerged in late 2022.

17 Jan 2023

SARS News and Research

Study finds fewer cases of MIS-C during omicron wave of the pandemic than delta

Exploring the infectivity, transmissibility, and immunological resistance characteristics of SARS-CoV-2 Omicron XBB.1.5 strain

Long-term, COVID-19-related smell loss could be treated using injections of platelet-rich plasma

Researchers find that study results converge on a consistent relationship between antibody levels and protection from COVID-19

How is long COVID diagnosed in adults?

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

New study highlights the under-reporting of COVID-19 deaths in the US

New research reveals that childhood omicron infections have been under-reported in Canadian schools

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Diagnosis and treatment of people with long COVID

Does COVID-19 cause adverse pregnancy and neonatal outcomes?

T-cell immunity and antibody responses against SARS-CoV-2 among individuals registered in the Bangkok home health care service

Epitope mapping reveals the humoral responses against the main SARS-CoV-2 structural proteins in infected patients from Africa

Study sheds new light on how the B cell academy mounts a diverse immune response

Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variants

What does the future of clinical trials and evidence-based medicine look like?

The efficacy of low-dose fluvoxamine compared with placebo for treating mild to moderate COVID-19 in the US

Upregulation of Robo4 expression reduces mortality from severe infection

Exploring a novel amplicon-based mpox virus sequencing strategy

The "Great Escape" by SARS-CoV-2 XBB.1

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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