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Taurine deficiency in sperm linked to male infertility

Sperm are highly specialized cells adapted to achieve a single goal: fertilize an egg. Along the road to fertilization sperm must embark on a lengthy journey to the female oviduct, avoiding several fatal stresses that occur when they pass through different physiological environments.

11 May 2018

CRISPR-based treatment can restore retinal function in mice with eye disease

Researchers from Columbia University have developed a new technique for the powerful gene editing tool CRISPR to restore retinal function in mice afflicted by a degenerative retinal disease, retinitis pigmentosa.

11 May 2018

New tool provides high accuracy and precision in analyzing disease and drug effects

A new protein analysis tool developed at the University at Buffalo could vastly increase the speed and precision with which disease and drug effects are analyzed.

11 May 2018

Scientists discover a mechanism through which HIV determines the fate and function of cells

A stem cell is one with infinite possibilities. So, for decades, scientists have puzzled over how the cell chooses to keep being a stem cell and continue dividing, or specialize into a specific cell type, like a heart or brain cell.

11 May 2018

New studies use proteomics to shed light on pathogenic mechanisms

Recent studies in the journal Molecular & Cellular Proteomics have shed light on pathogenic mechanisms of the sexually-transmitted parasite Trichomonas vaginalis and the HIV-associated opportunistic lung fungus Aspergillus.

11 May 2018

UAB researchers unravel brain neuron dysfunction in Parkinson’s disease and dementia with Lewy bodies

A decay of brain function is a hallmark of Parkinson's disease and dementia with Lewy bodies, or DLB. Specifically, cognitive dysfunction defines DLB, and nearly eight of every 10 Parkinson's patients develop dementia.

11 May 2018

Depleted metabolic enzymes contribute to tumor growth in renal cancer

Kidney cancer, one of the ten most prevalent malignancies in the world, has increased in incidence over the last decade, likely due to rising obesity rates.

10 May 2018

Scientists identify mutation that makes tumor cells resistant to breast and ovarian cancer drug

Scientists have identified a mutation that gives cancer cells resistance to the breakthrough cancer treatment olaparib and other PARP inhibitors.

10 May 2018

Study: Different strains of same protein may contribute to different Parkinson's-related brain disorders

Different Parkinson's-related brain disorders, called synucleionpathies, are characterized by misfolded proteins embedded in cells.

10 May 2018

Study discovers genetic variations that increase heart attack risk for statin patients

A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.

10 May 2018

Researchers identify six genes that predispose carriers to develop medulloblastoma

Researchers have identified six genes that predispose carriers to develop the brain tumor medulloblastoma and have used the discovery to craft genetic counseling and screening guidelines. The study appears today in the journal The Lancet Oncology.

10 May 2018

New research may help elucidate racial differences in prostate cancer

New research published in Molecular Oncology may help explain why African American men are at a higher risk of being diagnosed with prostate cancer and a higher risk of dying from the disease compared with European American men.

9 May 2018

Shiga toxin-producing E. coli found in animal and plant based foods

Escherichia coli (E. coli) is a germ that occurs naturally in the gut of mammals and birds, as well as in the human intestinal flora. However, certain E. coli types can cause severe diarrhea in humans.

9 May 2018

Johns Hopkins researchers identify protein clumps in diseased hearts

Similar to how protein clumps build up in the brain in people with some neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, protein clumps appear to accumulate in the diseased hearts of mice and people with heart failure, according to a team led by Johns Hopkins University researchers.

9 May 2018

Scientists use X-ray laser to gain insights into structure of Alzheimer's proteins

A new experimental method permits the X-ray analysis of amyloids, a class of large, filamentous biomolecules which are an important hallmark of diseases such as Alzheimer's and Parkinson's.

9 May 2018

Research findings could lead to new therapies to curb ovarian cancer metastasis

In order to spread their destruction, ovarian cancer cells must break free from their tumor home, travel through the fluid in the peritoneal cavity and attach to the outside of the abdominal organs--surfaces that are, by necessity, not sticky.

9 May 2018

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

TRAIL, a member of the TNF family of ligands, causes caspase-dependent apoptosis through activation of its receptors, death receptor 4 and DR5.

9 May 2018

Allen Institute for Cell Science launches first predictive and comprehensive, 3D model of live human cell

The Allen Institute for Cell Science today launched the first predictive and comprehensive, 3D model of a live human cell, the Allen Integrated Cell.

9 May 2018

Baldness treatment using a medication for osteoporosis

According to researchers, a drug used to treat patients with osteoporosis may soon be helpful in treating baldness. The study was published in the latest issue of the journal PLOS Biology this week.

9 May 2018

Scientists discover how potential new drug targets spinal muscular atrophy

Spinal muscular atrophy (SMA) is a genetic disease that can leave infants with weak muscles and trouble breathing. Many with the disease die before age two. To help these patients, doctors need therapies that target the genetic mutation and stop its progression.

8 May 2018

Protein C News and Research

Taurine deficiency in sperm linked to male infertility

CRISPR-based treatment can restore retinal function in mice with eye disease

New tool provides high accuracy and precision in analyzing disease and drug effects

Scientists discover a mechanism through which HIV determines the fate and function of cells

New studies use proteomics to shed light on pathogenic mechanisms

UAB researchers unravel brain neuron dysfunction in Parkinson’s disease and dementia with Lewy bodies

Depleted metabolic enzymes contribute to tumor growth in renal cancer

Scientists identify mutation that makes tumor cells resistant to breast and ovarian cancer drug

Study: Different strains of same protein may contribute to different Parkinson's-related brain disorders

Study discovers genetic variations that increase heart attack risk for statin patients

Researchers identify six genes that predispose carriers to develop medulloblastoma

New research may help elucidate racial differences in prostate cancer

Shiga toxin-producing E. coli found in animal and plant based foods

Johns Hopkins researchers identify protein clumps in diseased hearts

Scientists use X-ray laser to gain insights into structure of Alzheimer's proteins

Research findings could lead to new therapies to curb ovarian cancer metastasis

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

Allen Institute for Cell Science launches first predictive and comprehensive, 3D model of live human cell

Baldness treatment using a medication for osteoporosis

Scientists discover how potential new drug targets spinal muscular atrophy

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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