Protein C News and Research

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Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

A new study in Biological Psychiatry reports that dementia-related and psychiatric-related proteins cluster together to form aggregates in the brain, leading to abnormal cell function and behavior.

8 May 2018

Simple changes to diet could help reduce osteoarthritis symptoms

One gram of fish oil a day could help reduce the pain of patients with osteoarthritis, a new study in Rheumatology reports.

8 May 2018

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

Not all of your genome needs to be active at any given time. Some regions are prone to hopping around the genome in problematic ways if left unchecked; others code for genes that need to be turned off in certain cells or at certain times.

8 May 2018

PFKFB3 enzyme appears to play a key role in pulmonary hypertension

A new and early target for treating pulmonary hypertension appears to be an enzyme that's normally key to energy production but destructive in the face of this high blood pressure inside your lungs.

8 May 2018

Simplified Mammalian Cell Harvesting without Centrifuging

Centrifuging adds time and can potentially damage the cell sample, Michael Grauf discusses how cell clarification and sterile filtration can be achieved in one step.

From Sartorius 8 May 2018

Scientists discover how protein molecules regulate formation of myelin sheaths

According to the Deutsche Multiple Sklerose Gesellschaft, around 200,000 people in Germany suffer from multiple sclerosis- a serious neurological condition that has no known cure.

8 May 2018

New chemical trap catches trace glycoproteins, shows promise for targeted cancer treatments

Cancer drops sparse chemical hints of its presence early on, but unfortunately, many of them are in a class of biochemicals that could not be detected thoroughly, until now.

8 May 2018

New research identifies critical function of PDK1 pathway that contributes to cancer metastasis

Cancer is most devastating when it metastasizes--when tumor cells break away, travel through the bloodstream, and then attach elsewhere, only to grow another tumor.

8 May 2018

Study identifies new biomarker for early lung cancer diagnosis

High levels of cytoskeleton-associated protein 4 (CKAP4) have been identified in the blood of patients with lung cancer.

8 May 2018

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center.

8 May 2018

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus- they play an essential role in the survival of T cells.

8 May 2018

UH professor receives NIH grant to protect kidneys from obesity

UH professor of pharmacology Tahir Hussain has received $1.6M from the National Institutes of Health to examine a kidney cell that could prevent damage from inflammation caused by obesity.

7 May 2018

Study identifies molecule that may be critical to repair of white matter

A new study identifies a molecule that may be critical to the repair of white matter, the fatty tissue wrapped around parts of brain cells that helps speed up communication. Damage to white matter is associated with several conditions, including multiple sclerosis and cerebral palsy, and can occur in the brains of preterm babies.

7 May 2018

New study launched to examine effects of rheumatologic agent on bone health

Researchers at Hospital for Special Surgery have launched a pilot study to see how a drug that treats several related autoimmune disorders affects the skeleton.

7 May 2018

Diet may affect brain development in premature babies

The amount of carbohydrates, proteins and lipids consumed by vulnerable premature babies may significantly contribute to increased brain volume and white matter development.

7 May 2018

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Erythropoietin helps to protect and repair vulnerable brains though it remains a mystery how the anemia drug does so.

7 May 2018

Researchers discover how key brain receptor can function in hostile environment

During a stroke or an epileptic seizure, neurons in affected parts of the brain fire at an abnormally rapid rate.

7 May 2018

Fujitsu announces development of molecular simulation technology for drug discovery

Fujitsu Laboratories Ltd. and Fujitsu Limited today announced the development of molecular simulation technology for drug discovery that can accurately estimate binding affinity, which represents the degree to which proteins that can cause diseases (target proteins) bind to chemical substances that could become candidate drugs.

7 May 2018

New study aims to help clear up conflicting dietary advice around egg consumption

University of Sydney researchers aim to help clear up conflicting dietary advice around egg consumption, as a new study finds eating up to 12 eggs per week for a year did not increase cardiovascular risk factors in people with pre-diabetes and type 2 diabetes.

7 May 2018

Discovery could be used as starting point for development of new antibiotics

According to the WHO, around 700,000 people die every year as a result of antibiotic resistance. In Germany, around 6,000 people die every year because treatment with antibiotics is not effective.

7 May 2018

Protein C News and Research

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

Simple changes to diet could help reduce osteoarthritis symptoms

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

PFKFB3 enzyme appears to play a key role in pulmonary hypertension

Simplified Mammalian Cell Harvesting without Centrifuging

Scientists discover how protein molecules regulate formation of myelin sheaths

New chemical trap catches trace glycoproteins, shows promise for targeted cancer treatments

New research identifies critical function of PDK1 pathway that contributes to cancer metastasis

Study identifies new biomarker for early lung cancer diagnosis

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Nuclear pore complexes are critical for survival of circulating T cells, study shows

UH professor receives NIH grant to protect kidneys from obesity

Study identifies molecule that may be critical to repair of white matter

New study launched to examine effects of rheumatologic agent on bone health

Diet may affect brain development in premature babies

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Researchers discover how key brain receptor can function in hostile environment

Fujitsu announces development of molecular simulation technology for drug discovery

New study aims to help clear up conflicting dietary advice around egg consumption

Discovery could be used as starting point for development of new antibiotics

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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