Protein C News and Research

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Researchers uncover protein linked to breast cancer metastasis

Jean-François Côté, a researcher at the Montreal Clinical Research Institute and professor at Université de Montréal's Faculty of Medicine, studies metastasis, the leading cause of cancer-related death. Recently, his team uncovered a protein that, once deactivated, could prevent the development of metastases in an aggressive type of cancer, HER2-positive breast cancer.

7 May 2018

Key metabolites shed by gut bacteria can help protect from inflammation, study finds

Researchers at Tufts University have elucidated a mechanism by which the "good" bacteria that reside in our gastrointestinal tract can help protect us from inflammation, and how their disruption (dysbiosis) can increase the susceptibility of the liver to more harmful forms of disease.

4 May 2018

Researchers uncover novel approach for treating neuropathic pain

Neuropathic pain is the chronic, pathological pain that continues even when the cause of pain is removed. Causes include damage to nerve cells and medicines used to treat cancer.

4 May 2018

UTSW study provides insight into potential new therapeutic approaches for skin diseases

Research at UT Southwestern has shown that targeting metabolism in growing cells holds promise for the treatment of skin diseases like psoriasis that are characterized by skin overgrowth resulting from excess cell division, known as hyperproliferation.

4 May 2018

Unexpected discovery could improve detection of malaria infections

While the global health community has made great strides toward eradicating malaria through prevention and treatment strategies, rapid and inexpensive methods to diagnose submicroscopic malaria in individuals who have no clinical symptoms and undetectable levels of disease-causing parasites in their blood remain an unmet need.

4 May 2018

Surprising discovery offers new model for studying role of gap junctions in the brain

The same kind of neurons can have completely different wiring diagrams in the rat and mouse, as mice lack intercellular molecular channels known as gap junctions, researchers at Karolinska Institutet report in the scientific journal eLIFE.

4 May 2018

Osteoporosis drug prevents spread of basal-like breast cancer in mice

Researchers in China have discovered that an enzyme called UGT8 drives the progression of basal-like breast cancer, an aggressive form of the disease that is largely untreatable.

4 May 2018

Ocular oncologists link immunotherapy with potentially vision-robbing side effect

New immunotherapy treatments offer a remarkable chance for survival for patients with advanced melanoma and hard-to-treat cancers of the bladder, kidney and lung.

4 May 2018

Researchers discover how a light touch can lead to unbearable itching

For some people, particularly those who are elderly, even a light touch of the skin or contact with clothing can lead to unbearable itching.

4 May 2018

Study shows how bacterial toxins can cripple normal cellular activity

Bacterial toxins can wreak mass havoc within cells by shutting down multiple essential functions at once, a new study has found.

4 May 2018

Charles River Laboratories Expands Services for Early Discovery Screening

Charles River Laboratories International, Inc. recently announced the expansion of its service capabilities in early discovery screening.

4 May 2018

Combining natural cures with biomedical devices improves bone health, growth

A WSU research team is bringing together natural medical cures with modern biomedical devices in hopes of bringing about better health outcomes for people with bone diseases.

4 May 2018

Researchers characterize new protein that plays key role in genetic stability of cells

Researchers from the Novo Nordisk Foundation Center for Protein Research at the Faculty of Health and Medical Sciences have characterized a new protein that is important to the genetic stability of our cells.

3 May 2018

Novel PET tracer could provide early detection of rheumatoid arthritis

A novel PET tracer developed by Korean researchers can visualize joint inflammation and could provide early diagnosis of rheumatoid arthritis, a common autoimmune disease that causes chronic inflammation of joints and can lead to deformity and dysfunction.

3 May 2018

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

One major hallmark of cancer cells is their ability to adapt to stressful conditions such as nutrient deprivation. Rapidly growing tumor cells must compete for the ever-diminishing supply of nutrients in the surrounding environment to survive and proliferate. Targeting these adaptive mechanisms represents a promising approach for cancer therapeutics.

3 May 2018

Scientists discover mechanism behind unusual form of tissue regeneration in the liver

By studying a rare liver disease called Alagille syndrome, scientists from Cincinnati Children's and the University of California San Francisco (UCSF) have discovered the mechanism behind an unusual form of tissue regeneration that may someday reduce the need for expensive and difficult-to-obtain organ transplants.

3 May 2018

3D structures of nicotine receptor could lead to new ways for treating addiction

UT Southwestern researchers today published in Nature atomic-scale blueprints of the most abundant class of brain nicotinic acetylcholine receptors. A structural understanding of the protein, found in neurons, could lead to new ways to treat nicotine addiction from smoking and vaping.

3 May 2018

Protein C News and Research

Researchers uncover protein linked to breast cancer metastasis

Key metabolites shed by gut bacteria can help protect from inflammation, study finds

Researchers uncover novel approach for treating neuropathic pain

UTSW study provides insight into potential new therapeutic approaches for skin diseases

Unexpected discovery could improve detection of malaria infections

Surprising discovery offers new model for studying role of gap junctions in the brain

Osteoporosis drug prevents spread of basal-like breast cancer in mice

Ocular oncologists link immunotherapy with potentially vision-robbing side effect

Researchers discover how a light touch can lead to unbearable itching

Study shows how bacterial toxins can cripple normal cellular activity

Charles River Laboratories Expands Services for Early Discovery Screening

Combining natural cures with biomedical devices improves bone health, growth

Researchers characterize new protein that plays key role in genetic stability of cells

Novel PET tracer could provide early detection of rheumatoid arthritis

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

Scientists discover mechanism behind unusual form of tissue regeneration in the liver

3D structures of nicotine receptor could lead to new ways for treating addiction

Mother's milk found to have SWAT team of immune cells

UCLA researchers report promising drug strategy to block tau transmission

Scientists use cryo-ET techniques to capture images of measles viruses

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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