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New combination therapy could improve survival in children with high-risk neuroblastoma

Investigators at the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles provide preclinical evidence that the presence of tumor-associated macrophages--a type of immune cell--can negatively affect the response to chemotherapy against neuroblastoma.

25 Apr 2018

Key signaling protein in Huntington's disease found to have deleterious effects on heart function, shows study

Researchers investigating a key signaling protein in Huntington's disease describe deleterious effects on heart function, going beyond the disease's devastating neurological impact.

25 Apr 2018

Study explains how colon cancer cells spread to the liver

Colorectal cancer is the third most common cancer worldwide and the third-leading cause of cancer-related deaths. The main cause of death in patients with colorectal cancer is liver metastasis, with nearly 70% of patients eventually developing a liver tumor.

25 Apr 2018

Researchers identify novel pathway in development of AML with poor prognosis

Acute myeloid leukemia is a cancer of the blood and bone marrow that comprises 1% of all new cancer cases and almost 2% of cancer deaths in the U.S. The five-year survival rate for the disease is less than 20%.

24 Apr 2018

Researchers discover new gene associated with aortic aneurysms

An interdisciplinary team of researchers has identified a new gene linked to human aortic aneurysms. By combining comprehensive genetic studies in the fruit fly, dataset searches and analysis of diseased human aortic tissue, the researchers shed light on mechanisms not previously known to be associated with this devastating disease.

24 Apr 2018

Gene related to high fatality could be used as biomarker in patients with P. aeruginosa infection

Researchers discovered an easily measured gene linked to a high fatality rate, which could be used as a novel prognostic biomarker in patients with a Pseudomonas aeruginosa (P. aeruginosa) bloodstream infection, according to research presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases.

23 Apr 2018

Researchers identify superior blood-based biomarker for assessing sports-related concussions

A high-sensitive blood test can aid concussed hockey players when it might be safe to return to play. In a study published by the journal Neurology, researchers at Sahlgrenska Academy, Sweden, has identified a superior blood-based biomarker for assessing subtle brain injury.

23 Apr 2018

New drug treatment could be promising therapeutic approach for millions with asthma

Rutgers New Jersey Medical School researchers identified a new treatment that could lead to more effective drug therapy for millions of individuals with asthma and other respiratory disorders such as chronic obstruction pulmonary disease.

23 Apr 2018

Promising cell study may offer new opportunities for treating Parkinson's disease

For the first-time there is the prospect of medical doctors and researchers being able to alleviate the serious symptoms that follow with Parkinson's disease.

23 Apr 2018

Probiotics can improve liver health, shows study

Increased awareness of the importance of the microbes that live in our gut has spurred a great deal of research on the microbiome and fueled a booming probiotics industry. A new study suggests probiotics can improve not only the health of our gut but liver health, as well.

23 Apr 2018

Researchers identify target gene in P. aeruginosa infection

Researchers have discovered a gene linked to fatal outcomes in Pseudomonas aeruginosa (P. aeruginosa) infection that could be used as a novel prognostic biomarker and treatment target.

23 Apr 2018

Salamander study provides clues for treating spinal cord injuries

One of the most vexing problems with spinal cord injuries is that the human body does not rebuild nerves once they have been damaged. Other animals, on the other hand, seem to have no problem repairing broken neurons.

23 Apr 2018

Higher consumption of fish linked to better neurological health

A new study from Chalmers University of Technology, Sweden, shines more light on the link between consumption of fish and better long-term neurological health.

23 Apr 2018

Innovative research could lead to new ways to treat, prevent cancer

Research into cancer can provide new insight into how this disease works and how it can be stopped. The Experimental Biology 2018 meeting will showcase innovative research that could lead to new ways to treat and prevent cancer.

23 Apr 2018

Research offers new hope for healing wounds in patients with diabetes

One of the most frustrating and debilitating complications of diabetes is the development of wounds on the foot or lower leg. Once they form, they can persist for months, leading to painful and dangerous infections.

23 Apr 2018

New studies related to causes of liver degradation and possible treatments

A treatment gap remains for many conditions involving damage to the liver, the body's main organ for removing toxins, among other functions. The Experimental Biology 2018 meeting (EB 2018) will feature important research announcements related to the causes of liver degradation and possible treatments.

23 Apr 2018

Newly developed drug compound may help treat Charcot-Marie-Tooth disease

Scientists have developed a new drug compound that shows promise as a future treatment for Charcot-Marie-Tooth disease, an inherited, often painful neurodegenerative condition that affects nerves in the hands, arms, feet and legs.

20 Apr 2018

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

Scientists at Christiana Care Health System's Gene Editing Institute have developed a potentially breakthrough CRISPR gene-editing tool. It could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and quickly and precisely engineer multiple changes to the genetic code, according to a new study published today in the CRISPR Journal.

20 Apr 2018

Study reveals surprising insights into RNA-binding proteins

A host of special molecules called nuclear RNA-binding proteins (RBPs), when misplaced outside the nucleus, form the harmful clumps seen in several brain disorders, including frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).

20 Apr 2018

UConn researchers develop new composite for healing broken load-bearing bones

University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.

20 Apr 2018