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New CRISPR tool allows DNA editing outside of the cell

Researchers have developed a cell free method of gene editing, which uses a new version of the CRISPR tool that can edit DNA outside of the cell. This technique could revolutionize cancer care.

20 Apr 2018

Novel gold nanoparticle technology could guide cancer treatment in real-time

A new blood test using gold nanoparticles could soon give oncologists an early and more accurate prognosis of how cancer treatment is progressing and help guide the on-going therapy of patients.

20 Apr 2018

Consumption of protein supplements with meals may provide better weight control

A new systematic review of available evidence appearing in Nutrition Reviews, published by Oxford University Press, indicates that consuming protein supplements with meals may be more effective at promoting weight control than consuming supplements between meals in adults following an exercise regimen.

20 Apr 2018

AYOXXA to develop multiplex immunoassay to support treatment of sepsis patients

AYOXXA Biosystems GmbH, an international biotechnology company, will develop a multiplex assay to support the treatment of sepsis patients as part of the project "SepsisData.Net.NRW - Digitized Pattern Recognition for Personalized Treatment of Sepsis Patients". The development will be based on the Company’s innovative bead-based protein analysis platform LUNARIS™.

20 Apr 2018

AYOXXA introduces new LUNARIS Mouse 12-Plex Th17 Kit for quantitative analysis of Th17 cell biology

AYOXXA Biosystems GmbH, an international biotechnology company, focused on the development of innovative multiplex protein analysis technologies enabling translational research in basic and clinical research, today announced the expansion of its catalogue of immunoassays for multiplex protein analysis with the introduction of LUNARIS™ Mouse 12-Plex Th17 Kit for the quantitative analysis of soluble mouse T helper 17 (Th17) cell-related markers.

20 Apr 2018

AYOXXA launches advanced low-volume beads-on-a-chip multiplex protein analysis system

AYOXXA Biosystems GmbH, an international biotechnology company, today announces the introduction of its advanced low-volume beads-on-a-chip multiplex protein analysis system. The LUNARIS™ system can be readily integrated into any laboratory routine and is optimized to provide easy-to-use, standardized workflow from sample to result.

20 Apr 2018

UT Southwestern researchers identify 170 potential therapeutic targets for lung cancer

After testing more than 200,000 chemical compounds, UT Southwestern's Simmons Cancer Center researchers have identified 170 chemicals that are potential candidates for development into drug therapies for lung cancer.

20 Apr 2018

Rare variants in non-coding DNA inherited from parents heighten autism risk

In recent years, researchers have firmly established that gene mutations appearing for the first time, called de novo mutations, contribute to approximately one-third of cases of autism spectrum disorder.

20 Apr 2018

Long-term exposure to cold temperatures reduces diabetes and obesity, shows study

A new study in fat cells has revealed a molecular mechanism that controls how lifestyle choices and the external environment affect gene expression.

19 Apr 2018

New microscopy techniques allow quasi-biochemical studies on living T cells

A joint study by the TU Wien and the Vienna School of Medicine has now led to a surprising result. While most opinion leaders in the field reasoned that T cell receptors must interact with one another for effective immune-signaling, the Viennese study shows: T cell receptors act alone. The study has now been published in the journal Nature Immunology.

19 Apr 2018

Investigational drug may help increase protein levels in babies with spinal muscular atrophy

A preliminary study suggests that an investigational drug may help increase protein levels in babies with spinal muscular atrophy. The open-label study is released today and will be presented at the American Academy of Neurology's 70th Annual Meeting in Los Angeles, April 21 to 27, 2018.

19 Apr 2018

Genome editing identifies neural circuit behind leptin’s anti-obesity and anti-diabetes effects

Revealing surprising answers to a long-standing enigma about the brain target of the anti-obesity hormone leptin, neuroscientists at Tufts University School of Medicine have used CRISPR genome editing to identify a neural circuit in the hypothalamus as the primary mechanism in mediating leptin's anti-obesity and anti-diabetes effects and have identified two distinct mechanisms underlying leptin's inhibition of appetite.

19 Apr 2018

New insight may allow researchers to design drugs that improve immune responses to vaccines

Memory T cells are a critical element of our immune system's historical archive. To prevent repeat infections, these cells retain a record of germs they've fought before.

19 Apr 2018

Researchers use optogenetics to treat chronic pain

The finger prick from a thorn generates an immediate sensory response. In that instant, neurons at the injury site fire an electrical signal along a nerve fiber to the central nervous system. Our brain notes to avoid further encounters with thorns and the painful insult subsides.

18 Apr 2018