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'Cannibal drug' consumption in adolescence can increase vulnerability to cocaine use during adulthood

Consumption of the synthetic drug MDPV -a powerful psychostimulant known as 'cannibal drug'- in adolescence, can increase vulnerability of cocaine addiction during adulthood, according to a study carried out with laboratory animals and led by the researchers Elena Escubedo, from the Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine of the UB and Olga Valverde, head of the Neurobiology of Behaviour Research Group of Pompeu Fabra University.

22 Mar 2017

Philips announces results from clinical studies comparing iFR- and FFR-guided strategy for assessment of heart disease

Royal Philips today announced that the results from two large clinical trials comparing patient outcomes using instant wave-free ratio (iFR) and fractional flow reserve (FFR) in the diagnosis and treatment of heart disease have been published in the New England Journal of Medicine.

From Philips Healthcare 22 Mar 2017

MindMetre research note highlights exposure of oncology nurses to harmful effects of cytotoxic drugs

Independent research organisation MindMetre, which regularly addresses patient and healthcare worker safety across Europe, has examined evidence from qualitative interviews, clinical research and case studies that harm is being sustained by chemotherapy nurses in UK NHS Trusts as a result of exposure to hazardous cytotoxic drugs.

22 Mar 2017

Study to assess effectiveness of two OTC medications for treating alcoholism in bipolar patients

Researchers have long wondered if medications could treat alcohol abuse. Ihsan Salloum, M.D., chief of the Division of Alcohol and Drug Abuse at the University of Miami Miller School of Medicine, hopes to answer that question in part with a new clinical trial with E. Sherwood Brown, M.D., Ph.D., at UT Southwestern Medical Center in Dallas.

22 Mar 2017

Changes in the vascular system could play role in initiating Alzheimer’s disease

As the average age of Americans increases, so too does the problem of Alzheimer's, one of the world's most common neurological diseases. In recent years, scientists have explored many new approaches to clear the plaques and tangles in the brain that characterize the condition, but the new drugs have largely turned out to be disappointing.

22 Mar 2017

Direct-to-consumer ‘low-T’ medication advertising increases prescriptions but may not improve health

Direct-to-consumer advertising for drugs to treat testosterone deficiency -- or "low T" -- increases prescriptions to men for hormone-replacement therapies but may not improve their health, UC Davis physician Richard Kravitz said in an editorial published in the March 21 issue of the Journal of the American Medical Association.

22 Mar 2017

Researchers provide better understanding of the body's immune responses to implanted materials

Researchers at MIT and Boston Children's Hospital have published a report today in the journal Nature Materials that provides a better understanding of the body's immune responses to the materials used in implanted medical devices.

22 Mar 2017

FDA approves drug as add-on treatment for Parkinson's disease patients

The U.S. Food and Drug Administration today approved Xadago (safinamide) tablets as an add-on treatment for patients with Parkinson's disease who are currently taking levodopa/carbidopa and experiencing "off" episodes.

21 Mar 2017

Insulin resistance linked to more rapid decline in cognitive performance

A new Tel Aviv University study published in the Journal of Alzheimer's Disease finds that insulin resistance, caused in part by obesity and physical inactivity, is also linked to a more rapid decline in cognitive performance.

21 Mar 2017

New study correlates 80 cancer-related gene mutations with 34 AML subgroups

A large, new study of adults with acute myeloid leukemia (AML) correlates 80 cancer-related gene mutations with five subtypes of AML, which are defined by the presence of specific chromosomal abnormalities. The findings might help guide mutation testing and treatment decisions in the future.

21 Mar 2017

New research shows how to prevent prions from growing into deadly diseases

Prion diseases are scary, incurable and fatal. They first gained notoriety when cows became infected by prion proteins and, in turn, infected people. Fervor surrounding mad cow disease resulted in the U.S. banning imports of beef from the European Union for 15 years.

21 Mar 2017

Treatment with interferon may ease symptoms of Ebola patients

A pilot study of a class of drugs used to treat hepatitis and some forms of multiple sclerosis has been shown for the first time to ease symptoms of Ebola patients, while also increasing their survival.

21 Mar 2017

Shortage of low blood pressure drug for patients with septic shock linked to elevated risk of death

Patients with septic shock admitted to hospitals affected by the 2011 shortage of the drug norepinephrine had a higher risk of in-hospital death, according to a study published online by JAMA.

21 Mar 2017

Mouse study provides target for development of faster-acting antidepressant medications

Standard antidepressant medications don't work for everyone, and even when they do they are slow to kick in. In an effort to find better depression treatments, researchers at University of California San Diego School of Medicine discovered that inhibiting an enzyme called Glyoxalase 1 (GLO1) relieves signs of depression in mice.

21 Mar 2017

Penn scientists discover method that appears to provide early warning of transplant rejection

Approximately 30,000 organ transplants occur in the United States each year. However, between 20 and 50 percent—depending on the organ type—of the transplanted organs fail within five years, most often because the recipient's immune system attacks, or "rejects," the donated organ.

21 Mar 2017

High complexity cellular analysis with Beckman Coulter’s latest flow cytometer technology, the CytoFLEX LX

Beckman Coulter Life Sciences continues to expand the multi-parameter capabilities of its patented CytoFLEX flow cytometer technology.

From Beckman Coulter Life Sciences - Flow Cytometry 21 Mar 2017

New stenting tool found to be less painful and cheaper than current methods

A new tool for assessing the narrowing of the heart's arteries was found to be as effective as current methods and less painful for patients.

21 Mar 2017

New gene-silencing drugs cut cholesterol levels by half in early research

The first in a new class of gene-silencing drugs, known as inclisiran, has been shown to halve cholesterol levels in patients at risk of cardiovascular disease.

21 Mar 2017

Salk scientists develop new way to find responders to lithium therapy

For roughly one-third of people diagnosed with bipolar disorder, lithium is a miracle drug, effectively treating both their mania and depression. But once someone is diagnosed, it can take up to a year to learn whether that person will be among the 30 percent who respond to lithium or the 70 percent who do not.

21 Mar 2017

Researchers develop new way of visualizing distribution of cholesterol in cells, tissues

Researchers from UCLA and the University of Western Australia have developed a new way of visualizing the distribution of cholesterol in cells and tissues.

21 Mar 2017

Drugs News and Research

'Cannibal drug' consumption in adolescence can increase vulnerability to cocaine use during adulthood

Philips announces results from clinical studies comparing iFR- and FFR-guided strategy for assessment of heart disease

MindMetre research note highlights exposure of oncology nurses to harmful effects of cytotoxic drugs

Study to assess effectiveness of two OTC medications for treating alcoholism in bipolar patients

Changes in the vascular system could play role in initiating Alzheimer’s disease

Direct-to-consumer ‘low-T’ medication advertising increases prescriptions but may not improve health

Researchers provide better understanding of the body's immune responses to implanted materials

FDA approves drug as add-on treatment for Parkinson's disease patients

Insulin resistance linked to more rapid decline in cognitive performance

New study correlates 80 cancer-related gene mutations with 34 AML subgroups

New research shows how to prevent prions from growing into deadly diseases

Treatment with interferon may ease symptoms of Ebola patients

Shortage of low blood pressure drug for patients with septic shock linked to elevated risk of death

Mouse study provides target for development of faster-acting antidepressant medications

Penn scientists discover method that appears to provide early warning of transplant rejection

High complexity cellular analysis with Beckman Coulter’s latest flow cytometer technology, the CytoFLEX LX

New stenting tool found to be less painful and cheaper than current methods

New gene-silencing drugs cut cholesterol levels by half in early research

Salk scientists develop new way to find responders to lithium therapy

Researchers develop new way of visualizing distribution of cholesterol in cells, tissues

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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