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Study suggests a novel strategy to combat multidrug-resistant S. pneumoniae infections

Pneumococcal disease leads to over three million hospitalizations and hundreds of thousands of deaths annually.

17 Mar 2023

Study implicates gut microbiome and immune response in hospital-acquired infections

In a recent study published in the journal Nature Medicine, researchers at the University of Calgary analyzed the dynamics of fecal microbiota and conducted single-cell profiling of inflammatory responses and systemic immunity to determine associations between gut microbiome dysbiosis and an increased risk of nosocomial infections.

16 Mar 2023

Research highlights the importance of ventilation and air filtration to reduce pathogen transmission

Testing of ambient air can be used to monitor the community circulation of respiratory pathogens.

16 Mar 2023

A high-throughput CAMP assay for the evaluation of the vitamin D-dependent antimicrobial response

A recent developed a novel and high-throughput assay to evaluate cathelicidin antimicrobial peptide.

16 Mar 2023

Purine metabolite xanthine may play a role in Th17 cell differentiation in the gut

The gut is home to a cast of microbes that influence health and disease. Some types of microorganisms are thought to contribute to the development of inflammatory conditions, such as inflammatory bowel disease (IBD), but the exact cascade of events that leads from microbes to immune cells to disease remains mysterious.

16 Mar 2023

The role of the fungal mycobiome in women's health

Researchers discuss the association between human mycobiota and female health.

15 Mar 2023

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Researchers investigate the impact of intestinal microbiota dysbiosis on atherosclerotic cardiovascular disease incidence.

15 Mar 2023

Using probiotics to treat depression

Researchers discuss whether probiotics could be used as supplementary or primary therapy to manage major depressive disorder.

15 Mar 2023

New biomimetic model helps study wound healing in burn and laceration wounds

Burn wounds are notoriously prone to bacterial infection and typically lead to a larger amount of scar tissue than laceration wounds.

15 Mar 2023

Reversing infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein

Houston Methodist scientists reversed infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein, showing further evidence that links high cholesterol to female infertility.

15 Mar 2023

Age and sex determine the effects of microbiota on mice's metabolome

The gut handles all ingested foods for further digestion and assimilation. In addition, it harbors a wealth of microbes that produce metabolic byproducts with multiple effects on host physiology. Therefore, changes in the gut microbiome's composition can shift the gut's metabolome as well.

15 Mar 2023

How does the gut microbiome affect muscle strength?

Researchers use fecal microbiome transplantation in mouse models to examine the role of gut microbiota in determining muscle strength.

14 Mar 2023

Study identifies link between oral and gut microbiomes and depression

Researchers investigate the role of the oral-gut-brain axis in anxiety and depression.

14 Mar 2023

AI model empowers atopic dermatitis patients to detect complications from bacterial or viral infections

A team of dermatologists has developed an artificial intelligence (AI) model that empowers atopic dermatitis (AD) patients to detect complications from bacterial or viral infections and distinguish between eczema and skin lesions caused by a type of blood cancer.

14 Mar 2023

Long-term antibiotic therapy for adolescent acne can affect liver metabolism and promote adiposity

A growing body of evidence is showing that the healthy gut microbiome – a community of microorganisms that live together in the gut – influences many aspects of human growth and development, especially during adolescence.

14 Mar 2023

Host immune system forms small lesions in the intestines in response to bacterial infection

Yersinia bacteria cause a variety of human and animal diseases, the most notorious being the plague, caused by Yersinia pestis.

14 Mar 2023

The development of the pediatric oral resistome and its role in dental caries

Researchers performed a genomic investigation of oral resistome development, i.e., of genes that confer antimicrobial resistance.

14 Mar 2023

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

Researchers assessed the impact of the gut microbiome on the host's bile acid metabolism and intrahepatic cholestasis of pregnancy (ICP).

14 Mar 2023

The burden of Clostridioides difficile infections in the United States

Researchers review existing data on Clostridioides difficile infections among United States residents.

13 Mar 2023

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment.

13 Mar 2023

Bacterial News and Research

Study suggests a novel strategy to combat multidrug-resistant S. pneumoniae infections

Study implicates gut microbiome and immune response in hospital-acquired infections

Research highlights the importance of ventilation and air filtration to reduce pathogen transmission

A high-throughput CAMP assay for the evaluation of the vitamin D-dependent antimicrobial response

Purine metabolite xanthine may play a role in Th17 cell differentiation in the gut

The role of the fungal mycobiome in women's health

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Using probiotics to treat depression

New biomimetic model helps study wound healing in burn and laceration wounds

Reversing infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein

Age and sex determine the effects of microbiota on mice's metabolome

How does the gut microbiome affect muscle strength?

Study identifies link between oral and gut microbiomes and depression

AI model empowers atopic dermatitis patients to detect complications from bacterial or viral infections

Long-term antibiotic therapy for adolescent acne can affect liver metabolism and promote adiposity

Host immune system forms small lesions in the intestines in response to bacterial infection

The development of the pediatric oral resistome and its role in dental caries

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

The burden of Clostridioides difficile infections in the United States

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

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