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Approval of PD-1 inhibitor scratches surface of potential immunotherapies in recurrent HNSCC

The recent approval of pembrolizumab (Keytruda) in recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) following progression on a platinum-based chemotherapy was a significant advancement for the disease.

26 Sep 2016

Cesarean-section leaves women more vulnerable to VTE than vaginal delivery

Roughly one-third of all births in Europe and North America now occur via cesarean section (CS). Following any birth, women are at an increased risk for a venous thromboembolism (VTE), but it's believed that CS leaves women more vulnerable to VTE, blood clots, than vaginal delivery (VD).

22 Sep 2016

Scientists use novel theranostics technique for early thromboembolism diagnosis and treatment

Researchers from the University of Arkansas for Medical Science (USA), in collaboration with University Hospital Frankfurt and University Hospital Dresden, under the supervision of Prof. Vladimir Zharov and with the participation of Alexander Melerzanov, the dean of Department of Biological and Medical Physics (MIPT), conducted experiments on mice to detect blood clotting using photoacoustic flow-cytometry.

21 Sep 2016

Researchers report safety of laparoscopic sleeve gastrectomy from nationwide bariatric registry

By analyzing information included in the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program database, the largest bariatric-specific nationwide registry, researchers found that laparoscopic sleeve gastrectomy is a safe procedure with a low morbidity rate.

21 Sep 2016

Study shows continuous electrical stimulation suppresses seizures in patients with epilepsy

When surgery and medication don't help people with epilepsy, electrical stimulation of the brain has been a treatment of last resort.

20 Sep 2016

FDA authorizes marketing of new Aera system to treat patients with chronic ETD symptoms

The U.S. Food and Drug Administration today permitted marketing of a device that uses a small balloon to treat persistent Eustachian tube dysfunction (ETD), a condition in which pressure, pain or clogged or muffled sensations occur in the ear.

16 Sep 2016

New research seeks to find most effective medication for preventing life-threatening clots

Every year in the United States, thousands of high-risk fracture patients who have been admitted to trauma centers will suffer life-threatening blood clots related to the fracture. In rare cases these clots can even travel to the lungs, where they can cause sudden death.

16 Sep 2016

Article provides insights into nutrient-rich foods that can help prevent glaucoma

In general, I recommend that my patients include nutrient-rich foods such as fruits and vegetables as part of a healthy diet.

15 Sep 2016

Women, minorities less likely to receive stroke treatment, study finds

Women and minorities may be less likely to receive treatment for stroke, according to a study published in the September 14, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.

15 Sep 2016

Different types of stroke have diverse risk profiles in overweight or obese women

According to new research, women who are overweight or obese may have an increased risk of the most common kind of stroke, called ischemic stroke, but a decreased risk of a more often deadly stroke, called hemorrhagic stroke.

8 Sep 2016

Studies examine effectiveness of nasal sprays in reducing frequency, duration of HHT-related epistaxis

Two studies appearing in the September 6 issue of JAMA examine the effectiveness of nasal sprays to reduce the frequency and duration of nosebleeds caused by hereditary hemorrhagic telangiectasia (HHT), an inherited condition characterized by abnormal blood vessels which are delicate and prone to bleeding.

6 Sep 2016

EUS-FNA can help in effective management of worrisome pancreatic lesions

An endoscopic procedure can improve the outlook for patients with a fairly common type of pancreatic lesion that is challenging to manage and that, if left untreated, can progress to cancer, according to a study in the September issue of GIE: Gastrointestinal Endoscopy, the peer-reviewed journal of the American Society for Gastrointestinal Endoscopy.

2 Sep 2016

Induced deliveries following rupture of amniotic sac pose no increased risk to health of mother and infants

A new Tel Aviv University study has determined that natural, spontaneous deliveries and induced deliveries following the rupture of the amniotic sac in the mother share similar neonatal outcomes, contradicting common wisdom.

1 Sep 2016

REVERSE II trial validates HERDOO2 rule to help spot women who can discontinue anticoagulants

A clinical decision rule (CDR) that can be applied to women after a first, unprovoked venous thromboembolism (VTE) was able to identify those with a low-risk of recurrence who could safely discontinue anticoagulant therapy, researchers reported at ESC Congress 2016.

30 Aug 2016

New anticoagulant treatment safe and effective for AF patients before cardioversion

Patients with atrial fibrillation (AF) who need anticoagulation before undergoing electrical correction of their abnormal heartbeat (cardioversion) may benefit from treatment with edoxoban - a non-vitamin K antagonist (VKA) oral anticoagulant (NOAC), according to results of the ENSURE-AF trial.

30 Aug 2016

New study suggests major change in treatment of significant number of ACS patients

More than one quarter of heart attack patients who are normally treated with stents to re-open their blocked arteries might be able to forgo this procedure and receive anti-thrombotic medications only, according to results of a pilot study.

30 Aug 2016

Novel antidote effective in quickly reversing acute anticoagulant-related bleeding

A specially designed antidote to reverse acute, potentially life-threatening anticoagulant-related bleeding worked quickly, and was well-tolerated according to interim results of the ongoing ANNEXA-4 study.

30 Aug 2016

Platelet function testing in elderly patients after heart attack shows no improved outcomes

Monitoring platelet function in order to individualize antiplatelet therapy did not improve outcomes for elderly patients after a heart attack compared to a standard, unmonitored approach, results of the ANTARCTIC trial show.

29 Aug 2016

Active strategy of detecting and treating asymptomatic MSAD results in no clinical benefit

In patients with high-risk coronary artery disease (CAD), an active strategy of detecting and treating asymptomatic multisite artery disease (MSAD) combined with intensive medical therapy did not improve 2-year outcomes compared to a more traditional approach of managing only symptomatic coronary and extracoronary lesions, new research shows.

29 Aug 2016

Study results confirm safety and efficacy of INSIGHTEC’s Exablate Neuro system for the treatment of essential tremor

INSIGHTEC, the leader in MR-guided Focused Ultrasound (MRgFUS) therapy, has announced that the New England Journal of Medicine (NEJM) has published the results of a pivotal study of their Exablate Neuro system for the non-invasive treatment of essential tremor (ET). The study met its primary endpoint with patients treated with Exablate Neuro demonstrating a clinically significant 47% improvement in a composite tremor score at three months as compared to no change in the sham cohort.

29 Aug 2016

Bleeding News and Research

Approval of PD-1 inhibitor scratches surface of potential immunotherapies in recurrent HNSCC

Cesarean-section leaves women more vulnerable to VTE than vaginal delivery

Scientists use novel theranostics technique for early thromboembolism diagnosis and treatment

Researchers report safety of laparoscopic sleeve gastrectomy from nationwide bariatric registry

Study shows continuous electrical stimulation suppresses seizures in patients with epilepsy

FDA authorizes marketing of new Aera system to treat patients with chronic ETD symptoms

New research seeks to find most effective medication for preventing life-threatening clots

Article provides insights into nutrient-rich foods that can help prevent glaucoma

Women, minorities less likely to receive stroke treatment, study finds

Different types of stroke have diverse risk profiles in overweight or obese women

Studies examine effectiveness of nasal sprays in reducing frequency, duration of HHT-related epistaxis

EUS-FNA can help in effective management of worrisome pancreatic lesions

Induced deliveries following rupture of amniotic sac pose no increased risk to health of mother and infants

REVERSE II trial validates HERDOO2 rule to help spot women who can discontinue anticoagulants

New anticoagulant treatment safe and effective for AF patients before cardioversion

New study suggests major change in treatment of significant number of ACS patients

Novel antidote effective in quickly reversing acute anticoagulant-related bleeding

Platelet function testing in elderly patients after heart attack shows no improved outcomes

Active strategy of detecting and treating asymptomatic MSAD results in no clinical benefit

Study results confirm safety and efficacy of INSIGHTEC’s Exablate Neuro system for the treatment of essential tremor

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