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Nicotine promotes breast cancer lung metastasis, finds study

Breast cancer is the second most common cancer among women in the United States, and cigarette smoking is associated with a higher incidence of breast cancer spread, or metastasis, lowering the survival rate by 33% at diagnosis.

21 Jan 2021

Ethacrynic acid, a diuretic drug with potential anti-SARS-CoV-2 activity

A study published recently in the journal Viruses has identified a potent diuretic ethacrynic acid as an efficient inhibitor of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This drug can be potentially repurposed to treat coronavirus disease 2019 (COVID-19).

20 Jan 2021

Researchers discover potent antifungal agent from attine ant farms

Attine ants are farmers, and they grow fungus as food. Pseudonocardia and Streptomyces bacteria are their farmhands, producing metabolites that protect the crop from pathogens.

20 Jan 2021

Stanford study identifies a key factor in mental aging

Scientists have identified a key factor in mental aging and shown that it might be prevented or reversed by fixing a glitch in the immune system’s front-line soldiers.

20 Jan 2021

Novel non-steroid topical cream can safely and effectively treat plaque psoriasis

Psoriasis is a chronic inflammatory skin disease characterized by erythematous (red) patches and plaques.

19 Jan 2021

Stem cells with regenerative abilities could be closer on the horizon, shows study

A new type of stem cell - that is, a cell with regenerative abilities - could be closer on the horizon, a new study led by UNSW Sydney shows.

14 Jan 2021

Researchers develop a tiny, yet effective method for preventing premature birth

In a study in mice and human cells, Johns Hopkins Medicine researchers say that they have developed a tiny, yet effective method for preventing premature birth.

13 Jan 2021

Novel compound appears to protect myelin and nerve fibers

A compound developed at Oregon Health & Science University appears to protect nerve fibers and the fatty sheath, called myelin, that covers nerve cells in the brain and spinal cord.

13 Jan 2021

Medicinal plant-derived compound destroys brain-eating amoeba in lab studies

Primary amoebic meningoencephalitis (PAM), a deadly disease caused by the "brain-eating amoeba" Naegleria fowleri, is becoming more common in some areas of the world, and it has no effective treatment.

13 Jan 2021

Rotten egg gas may help protect aging brain cells from Alzheimer’s disease

Typically characterized as poisonous, corrosive and smelling of rotten eggs, hydrogen sulfide's reputation may soon get a face-lift thanks to Johns Hopkins Medicine researchers.

12 Jan 2021

Contamination-free Microplate Sealing for ADME Screening

BioChromato Inc. reports on how Pharmaceutical companies undertaking Absorption, Distribution, Metabolism and Excretion (ADME) studies are benefiting from integrating RAPID Easy Piercing Seals (EPS) into their screening protocols.

12 Jan 2021

Researchers identify bacterium that produces pharmaceutical all-purpose weapon

For some years, an active substance from the leaves of an ornamental plant has been regarded as a possible forerunner of a new group of potent drugs. So far, however, it has been very laborious to manufacture it in large quantities.

11 Jan 2021

Study: 20% of glioblastomas are fueled by overactive mitochondria

A new study has found that up to 20% of glioblastomas--an aggressive brain cancer--are fueled by overactive mitochondria and may be treatable with drugs currently in clinical trials.

11 Jan 2021

Potential role of chitinase 3-like-1 in severity of COVID-19

Now, an intriguing preprint research paper on the bioRxiv server reports the identification of an enzyme called chitinase 3-like-1 (CHI3L1) that mediates this age-dependent impact of the virus and could serve as a powerful therapeutic approach in mitigating the severity of COVID-19 in this high-risk group.

7 Jan 2021

Repurposed drug can treat hearing loss in humans

According to the World Health Organization, around 466 million people worldwide have disabling hearing loss, a number the organization projects will double by 2050 to affect 1 in 10 people.

7 Jan 2021

Main bioactive compound of ginger root may protect against autoimmune disease progression

Naturopathic medicine, or herbal medicine, is all the rage, especially among young people. But how much of this is supported by science?

6 Jan 2021

UCI study first to identify and characterize 'pharmacy deserts' in California

In the United States, Black, Latino and low-income communities have historically lacked nearby access to pharmacy services.

6 Jan 2021

Researchers identify natural products with potential to disrupt viral spread

Researchers at Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California San Diego have broken down the genomic and life history traits of three classes of viruses that have caused endemic and global pandemics in the past and identify natural products - compounds produced in nature - with the potential to disrupt their spread.

5 Jan 2021

Glycyrrhizin in licorice root neutralizes SARS-CoV-2 in vitro by inhibiting the main protease Mpro

In a recent bioRxiv* preprint paper, researchers from Germany analyzed aqueous licorice root extract for its neutralizing activity against SARS-CoV-2 in vitro. They identified glycyrrhizin, the primary active ingredient in the root, and revealed the underlying mechanism of viral neutralization.

5 Jan 2021

Study describes physician experiences with online harassment

While many physicians benefit from social media by networking with potential collaborators or interfacing with patients, a new study from Northwestern University and the University of Chicago found many physicians also report being sexually harassed and personally attacked on these platforms on the basis of their religion, race or medical recommendations.

4 Jan 2021