Enzyme News and Research

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Researchers develop a polyvalent lipid nanoparticle mRNA vaccine against Monkeypox virus

Researchers developed an mRNA technology-based vaccine candidate against the monkeypox virus and evaluated its immunogenicity in animal models.

5 Dec 2022

Researchers uncover the host protease CAPN2 as a novel host factor that aids the infection of SARS-CoV-2

Researchers investigated the potential of the CAPN2 molecule as a therapeutic target against SARS-CoV-2.

5 Dec 2022

Mucosal IgA fused nanobody as a non-invasive, cost-effective prophylaxis and therapeutic option against major SARS-CoV-2 variants

Researchers from the United States developed an affordable, non-invasive, inhalable prophylactic treatment consisting of immunoglobulin (Ig) A fused nanobodies against the SARS-CoV-2 Omicron variant.

2 Dec 2022

Novel biosensor enhances performance of home-based continuous glucose monitoring

Home-based continuous glucose monitoring for diabetics up to now has had to trade ease of use, low cost, and portability for a somewhat lower sensitivity - and thus accuracy - compared to similar systems in clinics or hospitals.

2 Dec 2022

Multiomics analysis of kidney metabolism reveals a gatekeeper for viral infections

Our kidney filters 180 liters of blood every day and retains nutrients through a process called 'endocytosis' and through active transport in the kidney cells.

2 Dec 2022

The effect of ubiquitination on SARS-CoV-2 infection and patient prognosis

A recent Clinical and Translational Medicine study utilized several published public datasets to evaluate the biological characteristics associated with the ubiquitination of patients infected with SARS-CoV-2.

2 Dec 2022

Antibody responses engendered by maternal SARS-CoV-2 vaccination following initial and booster doses in maternal circulation and breastmilk

Researchers investigated passive immunization of the fetus and neonates by evaluating the antibody responses elicited by primary and booster doses of maternal SARS-CoV-2 vaccination.

2 Dec 2022

Novel prefusion S antigen designed by the mutation of the SARS-CoV-2 Spike protein’s trimeric structure

Researchers mutated the SARS-CoV-2 spike protein's trimeric structure to design a novel prefusion S antigen, S2D14.

1 Dec 2022

Impact of COVID-19 on sperm quality

Researchers examined the effect of coronavirus disease 2019 (COVID-19) on sperm quality.

1 Dec 2022

SARS-CoV-2 can cause hyperglycemia in cats

In a recent study published in The Journal of Infectious Diseases, researchers explored the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hyperglycemia in cats.

30 Nov 2022

Understanding how the gut mycobiota respond to antibiotic treatment

Antibiotic treatment disrupts the balance of beneficial and harmful bacteria in a person's gut. That disruption can lead to the overgrowth of fungal species in the gut mycobiota, including the common intestinal yeast Candida albicans.

30 Nov 2022

Scientists discover how an enzyme involved in DNA repair becomes vital to tumor survival

Scientists at the Francis Crick Institute, in collaboration with Artios, have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the cancer cells lose the ability to use a more common method of DNA repair.

30 Nov 2022

Study suggests persistent immune activation and long COVID correlate independently with severe COVID-19

Researchers investigated whether severe COVID-19 patients exhibited inflammation and immune activation three months after hospitalization and explored the associations among COVID-19 severity, long COVID, and immune activation.

30 Nov 2022

Broadly cross-reactive antibodies that protect from SARS-CoV-2 variants are revealed by virus coldspot-driven discovery

A recent study identified neutralizing antibodies against conserved SARS-CoV-2 epitopes.

30 Nov 2022

The antibody resistance profile and viral receptor binding affinity of SARS-CoV-2 Omicron BQ.1, BQ.1.1, XBB, and XBB.1 subvariants

Researchers investigated the neutralizing antibody titers against the newly emergent BQ.1, BQ.1.1, XBB, and XBB.1 SARS-CoV-2 Omicron subvariants using sera from individuals with primary and booster COVID-19 vaccinations and previous SARS-CoV-2 infections.

30 Nov 2022

Meta-analysis reviews the incidence of new-onset diabetes in COVID-19 survivors

Researchers estimated the incidence of new-onset diabetes in survivors of coronavirus disease 2019 (COVID-19) employing random-effects meta-analyses using the generic inverse variance method.

30 Nov 2022

Pregnant people can safely take Paxlovid to reduce the possibility of severe COVID-19, study shows

Findings from a Johns Hopkins Medicine research study published today in JAMA Network Open provide strong evidence that people who are pregnant and have been infected with SARS-CoV-2 (the virus that causes COVID-19) can safely take the antiviral drug Paxlovid to reduce the possibility of severe disease.

29 Nov 2022

Antioxidant and anti-inflammatory properties of Stingless bee-derived propolis against acne

Researchers explore the anti-acne, antioxidant, and anti-inflammatory properties of Stingless bee (Tetragonula biroi)-derived propolis.

29 Nov 2022

New biosensing platform detects SARS-CoV-2 antibodies in five minutes

Rapid, cheap and accurate tests continue to be essential for epidemiological surveillance and for health services to monitor and contain the spread of SARS-CoV-2. Brazilian scientists have contributed to endeavors in this field by developing an electrochemical immunosensor that detects antibodies against the virus.

29 Nov 2022

SARS-CoV-2 Omicron variant tends to spread more easily among children than prior strains

Researchers estimate the age-varying susceptibility to infection with the SARS-CoV-2 Omicron variant.

28 Nov 2022

Enzyme News and Research

Researchers develop a polyvalent lipid nanoparticle mRNA vaccine against Monkeypox virus

Researchers uncover the host protease CAPN2 as a novel host factor that aids the infection of SARS-CoV-2

Mucosal IgA fused nanobody as a non-invasive, cost-effective prophylaxis and therapeutic option against major SARS-CoV-2 variants

Novel biosensor enhances performance of home-based continuous glucose monitoring

Multiomics analysis of kidney metabolism reveals a gatekeeper for viral infections

The effect of ubiquitination on SARS-CoV-2 infection and patient prognosis

Antibody responses engendered by maternal SARS-CoV-2 vaccination following initial and booster doses in maternal circulation and breastmilk

Novel prefusion S antigen designed by the mutation of the SARS-CoV-2 Spike protein’s trimeric structure

Impact of COVID-19 on sperm quality

SARS-CoV-2 can cause hyperglycemia in cats

Understanding how the gut mycobiota respond to antibiotic treatment

Scientists discover how an enzyme involved in DNA repair becomes vital to tumor survival

Study suggests persistent immune activation and long COVID correlate independently with severe COVID-19

Broadly cross-reactive antibodies that protect from SARS-CoV-2 variants are revealed by virus coldspot-driven discovery

The antibody resistance profile and viral receptor binding affinity of SARS-CoV-2 Omicron BQ.1, BQ.1.1, XBB, and XBB.1 subvariants

Meta-analysis reviews the incidence of new-onset diabetes in COVID-19 survivors

Pregnant people can safely take Paxlovid to reduce the possibility of severe COVID-19, study shows

Antioxidant and anti-inflammatory properties of Stingless bee-derived propolis against acne

New biosensing platform detects SARS-CoV-2 antibodies in five minutes

SARS-CoV-2 Omicron variant tends to spread more easily among children than prior strains

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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Evaluating new approaches for rare disease genomics

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