Immune Response News and Research

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New studies improve understanding of the genetic factors that protect people against COVID-19

Two recent papers by Brazilian researchers have contributed to the scientific understanding of the genetic factors that protect people against infection by SARS-CoV-2 or prevent progression to severe COVID-19.

21 Nov 2022

Additional mRNA COVID vaccine doses could salvage antibody responses in blood cancer patients

A third COVID-19 vaccine dose in this patients with blood cancers could enhance their antibody responses against SARS-CoV-2

21 Nov 2022

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

On November 17, 2022, the US Food and Drug Administration (FDA) approved a pathbreaking new drug called Tzield. This injectable formulation contains a combination of two drugs that could push back the onset of type 1 diabetes (T1D) in adults at stage 3 and children aged eight years or more at stage 2.

20 Nov 2022

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

A Ludwig Cancer Research study has revealed a single protein expressed at high levels by cancer cells across a broad range of malignancies that erects a multifaceted barrier to anti-cancer immune responses in mouse models of cancer and so shields tumors from immune detection and destruction.

20 Nov 2022

Researchers develop new device to non-invasively measure cervical nerve activity

A team of engineers and physicians at University of California San Diego has developed a device to non-invasively measure cervical nerve activity in humans, a new tool that they say could potentially inform and improve treatments for patients with sepsis, a life-threatening response to infection, and mental health conditions, such as post-traumatic stress disorder (PTSD).

20 Nov 2022

How gut microbes influence immune response to SARS-CoV-2

An article published in Critical Reviews in Food Science and Nutrition journal provides an overview of the role of gut microbiota in shaping the host immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Nov 2022

Comparing post–COVID-19 symptoms two years after SARS-CoV-2 infection

Researchers compared the presence of post–coronavirus disease 2019 (COVID-19) symptoms among hospitalized and non-hospitalized patients in Spain.

17 Nov 2022

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Researchers characterized the expression of IFN-1 and IFN-2, ISGs, and NF-κB in the upper respiratory tracts of patients with mild and severe COVID-19, to understand innate immune responses to SARS-CoV-2 infections.

17 Nov 2022

SARS-CoV-2 infection triggers reactivation of latent viruses in people with chronic fatigue syndrome

COVID-19 reactivated viruses that had become latent in cells following previous infections, particularly in people with chronic fatigue syndrome, also known as ME/CFS.

16 Nov 2022

Birth delivery method associated with baby’s immune response to key childhood vaccines

The method by which a baby was delivered is associated with how its immune system will respond to two key childhood vaccines, research suggests.

16 Nov 2022

Research reveals new treatment avenue for pediatric high grade gliomas harboring a genetic mutation

Researchers at the University of Michigan Rogel Cancer Center have identified a novel treatment approach to an aggressive type of pediatric brain cancer, using therapies already approved to treat cancer.

16 Nov 2022

Novel nasal vaccine approach induces potent lung immunity and protection against SARS-CoV-2

Researchers from the Centenary Institute and the University of Sydney have developed a new nasal vaccination strategy that induces potent lung immunity and protection against the SARS-CoV-2 coronavirus.

16 Nov 2022

COVID-19 mRNA boosters induce robust but non-durable immune response in the elderly

A study published in the journal Frontiers in Immunology describes that the third booster dose of coronavirus disease 2019 (COVID-19) effectively induces an immune response against immunologically more fit variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the immunity induced by the booster vaccination is transient and gradually declines over time.

15 Nov 2022

Polyphenols in Mediterranean diet may modulate COVID-19 inflammation

Researchers discuss the beneficial role of polyphenolic plant compounds in the Mediterranean diet in the prevention and treatment of COVID-19.

15 Nov 2022

Researchers identify 35 genes that are highly expressed in patients with long-term Lyme disease

Researchers at the Icahn School of Medicine at Mount Sinai in New York have identified 35 genes that are particularly highly expressed in people with long-term Lyme disease.

15 Nov 2022

Study highlights link between the induction of fever and antibody levels after COVID-19 mRNA vaccine

mRNA vaccines for COVID-19 generate adverse reactions such as fever and fatigue which are considered normal and are transient in nature.

15 Nov 2022

Certain TB correlates of protection linked with the likelihood of becoming infected with Mycobacterium tuberculosis

Researchers from the University of Oxford have today reported findings from a study that investigated whether previously identified correlates of protection associated with risk of full-blown tuberculosis (TB) disease could also be associated with risk of infection from the bacteria that causes TB.

15 Nov 2022

Immune Response News and Research

New studies improve understanding of the genetic factors that protect people against COVID-19

Additional mRNA COVID vaccine doses could salvage antibody responses in blood cancer patients

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

Researchers develop new device to non-invasively measure cervical nerve activity

How gut microbes influence immune response to SARS-CoV-2

Comparing post–COVID-19 symptoms two years after SARS-CoV-2 infection

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

SARS-CoV-2 infection triggers reactivation of latent viruses in people with chronic fatigue syndrome

Birth delivery method associated with baby’s immune response to key childhood vaccines

Research reveals new treatment avenue for pediatric high grade gliomas harboring a genetic mutation

Novel nasal vaccine approach induces potent lung immunity and protection against SARS-CoV-2

COVID-19 mRNA boosters induce robust but non-durable immune response in the elderly

Polyphenols in Mediterranean diet may modulate COVID-19 inflammation

Researchers identify 35 genes that are highly expressed in patients with long-term Lyme disease

Study highlights link between the induction of fever and antibody levels after COVID-19 mRNA vaccine

Certain TB correlates of protection linked with the likelihood of becoming infected with Mycobacterium tuberculosis

Minimally invasive reporter system allows highly sensitive monitoring of RNA production

Study points to a pathogenic role for compromised anti-SARS-CoV-2 responses in cerebrospinal fluid

Researchers provide new insights into the vexing process that makes HIV stealthy

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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