Mouse Model News and Research

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Developing innovative radiation treatment for inoperable brain and spinal tumors

An innovative radiation treatment that could one day be a valuable addition to conventional radiation therapy for inoperable brain and spinal tumors is a step closer, thanks to new research led by University of Saskatchewan (USask) researchers at the Canadian Light Source (CLS).

13 May 2020

Research identifies a disease trigger for pancreatitis

One factor contributing to the development of pancreatitis lies in mutations within a cell membrane ion channel that is characterized by its specific permeability for calcium ions.

13 May 2020

Abnormal calcium levels in mitochondria may cause neuronal cell death in Alzheimer's disease

For the first time, using a mouse model of Alzheimer's disease, scientists have documented a link between raised levels of calcium in mitochondria and neuronal death in the living brain.

13 May 2020

Study: New combination treatment significantly improves degenerative joint diseases

Hutchinson-Gilford Progeria Syndrome (HGPS) is a fatal condition that is especially prevalent in the skin, cardiovascular and the musculoskeletal systems. There exists a wide gap between existing knowledge of the disease and a potential treatment or cure.

12 May 2020

COVID-19 could accelerate activation of dormant tuberculosis (TB)

The ongoing COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has thrown much of the world into disarray, with over 4 million people reported infected and well over 282,000 deaths. A new study published on the preprint server bioRxiv in May 2020 suggests that the long-term impact of the virus could include activation of dormant bacterial infections like tuberculosis (TB).

10 May 2020

Texas A&M study offers hope for young children diagnosed with Menkes disease

A Texas A&M AgriLife Research team has good news for patients with copper-deficiency disorders, especially young children diagnosed with Menkes disease.

9 May 2020

New discovery could end chronic rejection of transplanted organs

Chronic rejection of transplanted organs is the leading cause of transplant failure, and one that the field of organ transplantation has not overcome in almost six decades since the advent of immunosuppressive drugs enabled the field to flourish.

9 May 2020

RNA interference machinery influences epithelial cell biology

Epithelial cells are held together and connected by several different types of structures that form cell-cell contacts.

9 May 2020

New compound significantly reduces multiple pathologies linked to Alzheimer's disease

When tested in brain cells and in a mouse model of Alzheimer's disease, a new compound significantly reduced the number of amyloid plaques in the brain, lessened brain inflammation and diminished other molecular markers of the disease.

8 May 2020

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

An international team led by Emory scientists has gained insight into the pathological mechanisms behind two devastating neurodegenerative diseases.

6 May 2020

Study explores maternal infection and its role in neurodevelopmental disorders

The immune responses of a female mouse before pregnancy can predict how likely her offspring are to have behavioral deficits if the immune system is activated during pregnancy, according to researchers from the Center for Neuroscience at the University of California, Davis.

5 May 2020

Bioactive lipids are key for diagnosis and treatment of cardiac repair after heart attack

Black men and women have higher incidences than whites of developing advanced heart failure following a heart attack.

5 May 2020

Loss of smell may be related to neuroinvasive propensity of SARS-CoV-2

The novel coronavirus has rapidly infected millions over the world in over 187 countries and territories, causing hundreds of thousands of deaths. One of the often-neglected and under-reported symptoms of the virus is the loss of the sense of smell or anosmia. Now, a new study out of Germany published on the preprint server medRxiv in April 2020 provides a quantified estimate of the magnitude of anosmia as a symptom of the coronavirus.

4 May 2020

Study finds Lin28 as promising therapeutic target for central nervous system injuries

Like power lines in an electrical grid, long wiry projections that grow outward from neurons - structures known as axons - form interconnected communication networks that run from the brain to all parts of the body.

2 May 2020

Researchers develop a new way to treat chronic pain

Researchers from the University of Copenhagen have developed a new way to treat chronic pain which has been tested in mice. With a compound designed and developed by the researchers themselves, they can achieve complete pain relief.

30 Apr 2020

Study explores molecular connections between genetics, gut microbiome and memory

A new study is among the first to trace the molecular connections between genetics, the gut microbiome and memory in a mouse model bred to resemble the diversity of the human population.

29 Apr 2020

CNIC researchers develop mouse model to examine the mechanical function of proteins

The Molecular Mechanics of the Cardiovascular System group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), led by Jorge Alegre Cebollada, in partnership with an international scientific team, has generated the first experimental mouse model that allows direct analysis of the mechanical function of proteins in living organisms.

28 Apr 2020

Mouse Model News and Research

Developing innovative radiation treatment for inoperable brain and spinal tumors

Research identifies a disease trigger for pancreatitis

Abnormal calcium levels in mitochondria may cause neuronal cell death in Alzheimer's disease

Study: New combination treatment significantly improves degenerative joint diseases

COVID-19 could accelerate activation of dormant tuberculosis (TB)

Texas A&M study offers hope for young children diagnosed with Menkes disease

New discovery could end chronic rejection of transplanted organs

RNA interference machinery influences epithelial cell biology

New compound significantly reduces multiple pathologies linked to Alzheimer's disease

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

Study explores maternal infection and its role in neurodevelopmental disorders

Bioactive lipids are key for diagnosis and treatment of cardiac repair after heart attack

Loss of smell may be related to neuroinvasive propensity of SARS-CoV-2

Study finds Lin28 as promising therapeutic target for central nervous system injuries

Researchers develop a new way to treat chronic pain

Study explores molecular connections between genetics, gut microbiome and memory

CNIC researchers develop mouse model to examine the mechanical function of proteins

Researchers report promising new therapy for recurrent pediatric brain cancers

New potential treatment candidate identified for early type 2 diabetic retinopathy

New study indicates novel therapies for Duchenne muscular dystrophy

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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