Nausea News and Research

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Nausea is the sensation of unease and discomfort in the upper stomach and head with an urge to vomit. An attack of nausea is known as a qualm.

Ceritinib ‘highly active’ in advanced ALK-rearranged NSCLC

Phase I study findings suggest the investigational drug ceritinib is effective in patients with advanced non-small-cell lung cancer with anaplastic lymphoma kinase gene rearrangement, even in those who develop resistance to crizotinib.

14 Apr 2014

Guidance on use of Tamiflu needs to be reviewed in light of most recent evidence

Tamiflu (the antiviral drug oseltamivir) shortens symptoms of influenza by half a day, but there is no good evidence to support claims that it reduces admissions to hospital or complications of influenza.

11 Apr 2014

Gilead Sciences announces positive results from LDV/SOF phase 2 studies on HCV infection

Gilead Sciences, Inc. (Nasdaq: GILD) today announced data from two Phase 2 studies evaluating investigational all-oral regimens containing the nucleotide analog polymerase inhibitor sofosbuvir (SOF) for the treatment of chronic hepatitis C virus (HCV) infection.

10 Apr 2014

Parkinson’s patients encouraged to order new Parkinson’s Passport to avoid medicine problems

This World Parkinson’s Day (11 April 2014) Parkinson’s Australia and NPS MedicineWise are encouraging anyone with Parkinson’s — or people caring for someone with the condition — to order a new Parkinson’s Passport to help avoid medicine problems.

9 Apr 2014

Janssen submits supplemental New Drug Application for IMBRUVICA to the U.S. FDA

Janssen Research & Development, LLC ("Janssen") today announced the submission of a supplemental New Drug Application (sNDA) for IMBRUVICA™ (ibrutinib) to the U.S. Food and Drug Administration (FDA) by its collaboration partner Pharmacyclics, Inc.

8 Apr 2014

Snowstorms, heavy storms that cause power outages may increase carbon monoxide poisoning

While preventable, carbon monoxide poisoning is a serious and sometimes fatal condition. Large weather events, such as snowstorms and heavy storms that cause power outages, can lead to an increase in the number of reported carbon monoxide exposures.

8 Apr 2014

Frail elderly people are at increased risk of death from outbreaks of viral gastroenteritis

Frail elderly people living in residential care facilities are at increased risk of severe illness or death from outbreaks of viral gastroenteritis.

3 Apr 2014

Neuroscientists find lateral habenula of brain controls sensitivity to negative effects of drinking alcohol

As recovering spring breakers are regretting binge drinking escapades, it may be hard for them to appreciate that there is a positive side to the nausea, sleepiness, and stumbling.

3 Apr 2014

L.A. Times: More than 9 million uninsured gain coverage

The newspaper's tally draws on state and federal enrollment reports, surveys by consultants and interviews with insurance and government officials. Meanwhile, insurers and others intensify efforts to sign up young customers.

1 Apr 2014

Heron initiates SUSTOL Phase 3 clinical trial for CINV prevention associated with emetogenic chemotherapy

Heron Therapeutics, Inc., a specialty pharmaceutical company, today announced the initiation of a Phase 3 clinical trial of SUSTOL™ (APF530), the Company's lead product candidate for the prevention of chemotherapy-induced nausea and vomiting (CINV) associated with moderately and highly emetogenic chemotherapy.

31 Mar 2014

FDA approves additional manufacturing suite for Pacira’s EXPAREL

Pacira Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration approved an additional bulk manufacturing suite, referred to as Suite C, for EXPAREL (bupivacaine liposome injectable suspension). The suite is housed at the company's Science Center Campus in San Diego, where EXPAREL is currently manufactured.

31 Mar 2014

First Edition: March 31, 2014

Today's early morning highlights from the major news organizations offer assessments of the administration's campaign to get people signed up for health care and a look at the issues going forward after today's deadline for most enrollments.

31 Mar 2014

Amgen reports positive findings from AMG 145 Phase 3 studies in patients at risk for cardiovascular disease

Amgen (NASDAQ: AMGN) today announced new detailed data from three Phase 3 studies that showed treatment with its novel investigational cholesterol-lowering medication, evolocumab (AMG 145), resulted in a statistically significant reduction of 55-66 percent in low-density lipoprotein cholesterol (LDL-C) compared to placebo in patients with high cholesterol.

31 Mar 2014

Novartis’ investigational compound achieves overall response rate of 58% in patients with ALK+ NSCLC

Novartis today announced that The New England Journal of Medicine (NEJM) published clinical trial results showing the investigational compound LDK378 (ceritinib) achieved an overall response rate (ORR, including complete response [CR] and partial response [PR]) of 58% and a median progression-free survival (PFS) of seven months in adults with advanced anaplastic lymphoma kinase positive (ALK+) non-small cell lung cancer (NSCLC) who received 400 mg or higher of LDK378 per day.

28 Mar 2014

CDC identifies six new cases of people with Heartland virus

The Centers for Disease Control and Prevention in collaboration with health officials in Missouri and Tennessee have identified six new cases of people sick with Heartland virus: five in Missouri and one in Tennessee. The new cases, discovered in 2012 and 2013, are described today in CDC's Morbidity and Mortality Weekly Report.

28 Mar 2014

Nausea News and Research

Further Reading

Ceritinib ‘highly active’ in advanced ALK-rearranged NSCLC

Guidance on use of Tamiflu needs to be reviewed in light of most recent evidence

Gilead Sciences announces positive results from LDV/SOF phase 2 studies on HCV infection

Parkinson’s patients encouraged to order new Parkinson’s Passport to avoid medicine problems

Janssen submits supplemental New Drug Application for IMBRUVICA to the U.S. FDA

Snowstorms, heavy storms that cause power outages may increase carbon monoxide poisoning

Frail elderly people are at increased risk of death from outbreaks of viral gastroenteritis

Neuroscientists find lateral habenula of brain controls sensitivity to negative effects of drinking alcohol

L.A. Times: More than 9 million uninsured gain coverage

Heron initiates SUSTOL Phase 3 clinical trial for CINV prevention associated with emetogenic chemotherapy

FDA approves additional manufacturing suite for Pacira’s EXPAREL

First Edition: March 31, 2014

Amgen reports positive findings from AMG 145 Phase 3 studies in patients at risk for cardiovascular disease

Novartis’ investigational compound achieves overall response rate of 58% in patients with ALK+ NSCLC

CDC identifies six new cases of people with Heartland virus

European Commission approves Exelixis' COMETRIQ for treatment of progressive, metastatic MTC

FDA approves Xolair for treatment of chronic idiopathic urticaria

ZL105 drug could potentially replace currently used anticancer drugs, study finds

Sea lions exposed to toxin in algae develop form of epilepsy that is similar to humans

Medivir announces phase III ATTAIN study of simeprevir inhibitor in treatment of adult patients with HCV

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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