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New way to promote insulin production in pre-diabetes phase discovered

Nanyang Technological University, Singapore scientists have discovered that a type of immune cell known as 'pancreatic islet macrophages' is capable of promoting insulin production during the pre-diabetes phase.

15 Nov 2019

Virtual cardiology follow-ups are a feasible alternative for pediatric cardiac conditions

Health provider follow-ups delivered via computer or smartphone is a feasible alternative to in-person patient follow-ups for some pediatric cardiac conditions, according to the findings of a pilot study presented at the AHA Scientific Sessions this week.

15 Nov 2019

Study: 15,000 cases of hypophosphatasia potentially undetected in Spanish population

Hypophosphatasia (HPP) is a rare and serious hereditary disease that is potentially life-threatening and is caused by one or more mutations in the gene coding for alkaline phosphatase (ALPL). It is frequently misdiagnosed.

15 Nov 2019

Mining 'darkest' parts of the genome in cancer cells yields gold

Mining the rich uncharted territory of the genome or genetic material of a cancer cell has yielded gold for Princess Margaret scientists: new protein targets for drug development against prostate cancer.

15 Nov 2019

Study: Many patients treated for iNPH also develop Alzheimer’s disease

Up to one in five patients treated for idiopathic normal pressure hydrocephalus, iNPH, also develop Alzheimer’s disease, according to a new study from the University of Eastern Finland and Kuopio University Hospital.

15 Nov 2019

New study aims to optimize brain development in babies with congenital heart disease

An upcoming clinical trial at Children's National Hospital will harness cardiopulmonary bypass as a delivery mechanism for a novel intervention designed to stimulate brain growth and repair in children who undergo cardiac surgery for congenital heart disease.

14 Nov 2019

Study unravels how insulin interacts with its receptor

Since the discovery of insulin nearly 100 years ago, scientists have explored how it interacts with its receptor with the goal of improving the ability of therapeutic insulins to mimic the way insulin works in the body.

14 Nov 2019

Woman with severe spinal cord injury recovers after treatment at Danbury Hospital

A freak accident left Katherine (Kathy) Wenning unable to move her upper body. She knew she needed medical attention, but she was at her country getaway in Washington, Connecticut - two hours by car from her home in Manhattan and the New York medical system she trusted.

14 Nov 2019

New research casts doubt on the credibility of China’s organ transplant datasets

The Chinese government may have been systematically misreporting the number of organs it claims it has voluntarily collected since 2010, according to new research published in BMC Medical Ethics.

14 Nov 2019

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA -- alterations in coding regions of the genome that can lead directly to changes in the expression of particular proteins important for a healthy body.

14 Nov 2019

WPI researchers developing miniaturized device to measure baby's blood oxygen levels

Researchers at Worcester Polytechnic Institute are developing a sensor the size of a Band-Aid that will measure a baby's blood oxygen levels, a vital indication of the lungs' effectiveness and whether the baby's tissue is receiving adequate oxygen supply.

14 Nov 2019

Improved method for predicting retinopathy of prematurity could reduce unnecessary tests

A multicenter group of 41 hospitals led by researchers at Children's Hospital of Philadelphia (CHOP) has confirmed that an improved method for predicting retinopathy of prematurity (ROP), a leading cause of blindness in children, was able to reduce the number of babies having invasive diagnostic examinations by nearly a third, while raising disease detection up to 100 percent.

14 Nov 2019

Study sheds light on how Zika virus causes microcephaly in newborns

A new study led by researchers at Baylor College of Medicine revealed how in utero Zika virus infection can lead to microcephaly in newborns. The team discovered that the Zika virus protein NS4A disrupts brain growth by hijacking a pathway that regulates the generation of new neurons.

14 Nov 2019

Earliest stage of hearing loss is linked to cognitive decline

Research has shown that adults with age-related hearing loss have higher rates of cognitive decline. Now, a study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found that even the earliest stage of hearing loss-when hearing is still considered normal - is linked to cognitive decline.

14 Nov 2019

New insights into how immune system and inflammation play a role in PD

Relatively new research findings indicating that the earliest stages of Parkinson's disease (PD) may occur in the gut have been gaining traction in recent years. In a review published in the Journal of Parkinson's Disease, Tomasz Brudek, PhD, evaluates evidence for the association between inflammatory bowel disease (IBD) and PD and proposes directions for future research.

14 Nov 2019

Bisphenol-s and bisphenol-f may have less impact on heart function than bisphenol-a

Some chemical alternatives to plastic bisphenol-a (BPA), which is still commonly used in medical settings such as operating rooms and intensive care units, may be less disruptive to heart electrical function than BPA, according to a pre-clinical study that explored how the structural analogues bisphenol-s (BPS) and bisphenol-f (BPF) interact with the chemical and electrical functions of heart cells.

14 Nov 2019

Antibiotic Resistance Threats report highlights significant gaps and impact of federal investments

The Antibiotic Resistance Threats Report released by the U.S. Centers for Disease Prevention and Control today shows that while recent federal investments to combat antibiotic resistance have had meaningful impacts, the continued spread of infections that are not effectively treated by existing medicines pose deadly threats to patients and public health.

14 Nov 2019

Study offers promising methodology to capture biomechanical behaviour of aneurysm

An abdominal aortic aneurysm is a focal dilation of the abdominal aorta, that if not treated, tends to grow and may rupture. The most common treatment is EndoVascular Aneurysm Repair (EVAR), which requires patients to undergo lifelong postoperative surveillance based on computed tomography angiography (CTA) due to the possible appearance of complications. These complications may again lead to aneurysm dilation and rupture.

14 Nov 2019

Researchers develop, test new blood assay that predicts patients at risk of death from sepsis

After decades of little or no progress, biomedical researchers are finally making some headway at detecting and treating sepsis, a deadly medical complication that sends a surge of pathogenic infection through the body and remains a major public health problem.

14 Nov 2019

Blocking a molecule could delay the progression of multiple sclerosis

Over 77,000 Canadians are living with multiple sclerosis, a disease whose causes still remain unknown. Presently, they have no hope for a cure.

14 Nov 2019

Hospital News and Research

New way to promote insulin production in pre-diabetes phase discovered

Virtual cardiology follow-ups are a feasible alternative for pediatric cardiac conditions

Study: 15,000 cases of hypophosphatasia potentially undetected in Spanish population

Mining 'darkest' parts of the genome in cancer cells yields gold

Study: Many patients treated for iNPH also develop Alzheimer’s disease

New study aims to optimize brain development in babies with congenital heart disease

Study unravels how insulin interacts with its receptor

Woman with severe spinal cord injury recovers after treatment at Danbury Hospital

New research casts doubt on the credibility of China’s organ transplant datasets

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

WPI researchers developing miniaturized device to measure baby's blood oxygen levels

Improved method for predicting retinopathy of prematurity could reduce unnecessary tests

Study sheds light on how Zika virus causes microcephaly in newborns

Earliest stage of hearing loss is linked to cognitive decline

New insights into how immune system and inflammation play a role in PD

Bisphenol-s and bisphenol-f may have less impact on heart function than bisphenol-a

Antibiotic Resistance Threats report highlights significant gaps and impact of federal investments

Study offers promising methodology to capture biomechanical behaviour of aneurysm

Researchers develop, test new blood assay that predicts patients at risk of death from sepsis

Blocking a molecule could delay the progression of multiple sclerosis

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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