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City of Hope researchers find how HER2-positive breast cancer patients develop brain metastases

Ninety percent of cancer deaths are from cancer spread. Breast cancer patients, for example, typically do not die because cancer returns in their breast, they die because it spreads to other parts of their body. The most dangerous of which is the brain.

2 Mar 2017

Researcher examines scarring process in hope of preventing chronic lung transplant rejection

For patients affected by lung diseases such as pulmonary fibrosis, chronic obstructive pulmonary disease, cystic fibrosis and others, cures for their diseases are incredibly rare, if not nonexistent.

2 Mar 2017

Study provides insights into how cancer cells can evade FGFR inhibitors

A new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute has identified a mechanism by which cancer cells develop resistance to a class of drugs called fibroblast growth factor receptor (FGFR) inhibitors.

2 Mar 2017

Researchers uncover mechanism that contributes to joint inflammation in rheumatoid arthritis patients

New research findings published in the Journal of Leukocyte Biology, suggest that synovial CD4+ T cells that produce IL-21 contribute to joint inflammation by activating synovial fibroblasts in rheumatoid arthritis patients.

2 Mar 2017

Study establishes ENL protein as potential drug target for acute myeloid leukemia

Anyone who uses an employee badge to enter a building may understand how a protein called ENL opens new possibilities for treating acute myeloid leukemia (AML), a fast-growing cancer of bone marrow and blood cells and the second most common type of leukemia in children and adults.

2 Mar 2017

New wireless patch may help reduce migraine pain as well as drugs, study suggests

A preliminary study suggests that a new, wireless patch that you wear on your arm may help reduce migraine pain as well as drugs. The study is published in the March 1, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology.

2 Mar 2017

Study shows new drug as promising treatment option for difficult-to-treat rheumatoid arthritis patients

Between 3 and 5% of the population suffer from a form of inflammatory rheumatism. It affects approximately 250,000 - 400,000 people in Austria.

2 Mar 2017

Cholesterol-processing enzyme could be therapeutic target to stave off neurologic diseases

An enzyme that helps break down cholesterol may also be a therapeutic target to stave off neurologic diseases, including Alzheimer's and a rare genetic disorder, according to a new study published in the Journal of Biological Chemistry.

2 Mar 2017

Researchers looking at ways to target lingering cancer stem cells that cause disease relapse

Chemotherapy treatment targets and kills cancer cells in the body. However, even after treatment, some cancer cells may remain in the patient's system undetected.

2 Mar 2017

Brains of adolescents with anorexia nervosa remain altered even after treatment, study finds

Even after weeks of treatment and considerable weight gain, the brains of adolescent patients with anorexia nervosa remain altered, putting them at risk for possible relapse, according to researchers at the University of Colorado Anschutz Medical Campus.

1 Mar 2017

Shared reading can be useful therapy for chronic pain sufferers, study finds

A study conducted by researchers from the University of Liverpool, The Reader and the Royal Liverpool University Hospitals Trust, and funded by the British Academy, has found that shared reading (SR) can be a useful therapy for chronic pain sufferers.

1 Mar 2017

Women less likely to be screened for heart disease risk factors than men, study finds

A new report has highlighted a gender divide in the screening of patients for cardiovascular disease - Australia's number one killer.

1 Mar 2017

Brown fat in humans three times greater than previously known, TUM study shows

Compared to white fat, brown body fat burns through energy at an extraordinary rate. However, until now the proportion of brown fat in humans was thought to be quite small.

1 Mar 2017

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Researchers at Monash University and Peter MacCallum Cancer Centre have identified for the first time how a new class of epigenetic drug engages with the immune system to kill off cancer cells, offering powerful new pathways for enhanced blood cancer therapies.

1 Mar 2017

Commonly-prescribed drug for treating weak bone condition linked to increased risk of 'micro-cracks'

A type of drug used to treat weak bones is associated with an increased risk of 'micro-cracks' in bone, according to new research.

1 Mar 2017

Compound from soil bacteria could translate into new drug lead for TB

A new treatment for tuberculosis (TB) is set to be developed using compounds derived from bacteria that live in soil - according an international collaboration of researchers, including the University of Warwick.

1 Mar 2017

Study highlights need to control doping problem in amateur sports

A study led by the University of Granada has shown that doping is not only a problem exclusive to professional sports, but also occurs in amateur sports.

1 Mar 2017

New BSR guideline provides evidence-based recommendations for clinicians prescribing non-biologic DMARDs

This latest guidance sets out evidence based recommendations for clinicians prescribing synthetic, non-biologic, anti-rheumatic drugs to tackle multisystem rheumatic conditions.

1 Mar 2017

Using Spherical Nucleic Acids to Track and Treat Disease

Spherical nucleic acids are structures that are made by taking a nanoparticle template and using chemistry to arrange short strands of DNA or RNA on the surface of those particles. The spherical core of the nanoparticle creates a spherical arrangement of DNA or RNA, similar to tiny little balls of nucleic acids.

From Pittcon 1 Mar 2017

New London Major Early-Phase Contract Research Center Opened on Rare Disease Day

Richmond Pharmacology, one of the UK’s leading early-phase contract research organisations, have today opened their new research facility in London Bridge – at the site formerly known as the Guy’s Drug Research Unit. The move is a significant boost to the UK’s efforts to continue to grow as a global hub for Life Sciences, an area of strategic importance outlined in the Government’s recent industrial strategy.

1 Mar 2017

Drugs News and Research

City of Hope researchers find how HER2-positive breast cancer patients develop brain metastases

Researcher examines scarring process in hope of preventing chronic lung transplant rejection

Study provides insights into how cancer cells can evade FGFR inhibitors

Researchers uncover mechanism that contributes to joint inflammation in rheumatoid arthritis patients

Study establishes ENL protein as potential drug target for acute myeloid leukemia

New wireless patch may help reduce migraine pain as well as drugs, study suggests

Study shows new drug as promising treatment option for difficult-to-treat rheumatoid arthritis patients

Cholesterol-processing enzyme could be therapeutic target to stave off neurologic diseases

Researchers looking at ways to target lingering cancer stem cells that cause disease relapse

Brains of adolescents with anorexia nervosa remain altered even after treatment, study finds

Shared reading can be useful therapy for chronic pain sufferers, study finds

Women less likely to be screened for heart disease risk factors than men, study finds

Brown fat in humans three times greater than previously known, TUM study shows

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Commonly-prescribed drug for treating weak bone condition linked to increased risk of 'micro-cracks'

Compound from soil bacteria could translate into new drug lead for TB

Study highlights need to control doping problem in amateur sports

New BSR guideline provides evidence-based recommendations for clinicians prescribing non-biologic DMARDs

Using Spherical Nucleic Acids to Track and Treat Disease

New London Major Early-Phase Contract Research Center Opened on Rare Disease Day

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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