Pharmaceuticals News and Research

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Re-engineered Gleevec reduces heart risks

Using a new bottom-up approach for rational drug design, researchers at Rice University and the University of Texas M. D. Anderson Cancer Center have reengineered the powerful anticancer drug imatinib - best known by its brand name Gleevec - to more specifically target one type of cancer while potentially curbing a rare life-threatening cardiotoxic side effect.

4 Dec 2007

Approval of Diovan (valsartan) in U.S. for hypertension in children and adolescents

Diovan (valsartan), an angiotensin receptor blocker or ARB, has been approved following a priority review by the U.S. Food and Drug Administration (FDA) for the treatment of high blood pressure in children and adolescents ages six to 16.

4 Dec 2007

Do medical schools affect the way future doctors interact with drug companies?

Although more and more drug advertisements are appearing on television, the bulk of the approximately $21 billion dollars that pharmaceutical companies spend annually to market their products is targeted to physicians, doctors in training (residents) and medical students.

3 Dec 2007

FDA issues approvable letter for Nebivolol for the treatment of hypertension

Forest Laboratories, Inc. and Mylan Inc. announced that Mylan has received an approvable letter from the U.S. Food and Drug Administration (FDA) in response to its New Drug Application (NDA) for nebivolol (proposed brand name Bystolic), a novel beta blocker under review for the treatment of hypertension.

2 Dec 2007

Stem cell technology pioneer, Plasticell secures funding

Plasticell is a biotechnology company that has developed and holds exclusive intellectual property rights for two complementary systems in the fields of stem cell research and regenerative medicine.

29 Nov 2007

Sirtris Pharmaceuticals unveils promising, novel SIRT1 activators for treating diseases of aging

Sirtris Pharmaceuticals has announced that findings in the journal Nature demonstrate that Sirtris has developed novel drug candidates that offer a promising, new approach to treating diseases of aging, including Type 2 Diabetes, by targeting SIRT1, a gene that controls the aging process.

29 Nov 2007

America's mental health ranked

Mental Health America has released its report, "Ranking America's Mental Health: An Analysis of Depression Across the States," a first-of-its-kind study examining state and national data for statistical associations between factors that govern access to mental health care and actual mental health outcomes, including suicide rates.

29 Nov 2007

New anti-infective drug aims to fight drug-resistant bacteria at source

Deadly methicillin-resistant Staphylococcus aureus - MRSA - a bacterium that responds poorly to conventional antibiotic treatment, infects 90,000 Americans per year and causes 19,000 deaths, most in hospital settings.

29 Nov 2007

Innovative drug production project secures funding from Technology Strategy Board

PolyTherics, a biopharmaceutical spin-out company from Imperial College London and the London School of Pharmacy, has announced that it has secured funding from the Technology Strategy Board.

29 Nov 2007

Genetic selection of target stem cell populations

Human embryonic stem cells can be genetically manipulated to help select out desirable cell types, according to a University of Nottingham study published online in Molecular Therapy.

29 Nov 2007

New computational technique predicts side-effects of a major cancer drug

Researchers at the University of California San Diego have developed a novel computer technique to search for the side effects of major pharmaceuticals.

29 Nov 2007

Watson Pharmaceuticals receives FDA approval for generic Combunox

Watson Pharmaceuticals, Inc. has announced that it has received final approval from the United States (U.S.) Food and Drug Administration (FDA) on its Abbreviated New Drug Application (ANDA) for Oxycodone Hydrochloride and Ibuprofen Tablets (CII) in the 5 mg/400 mg strength.

27 Nov 2007

Ikaria's INOmax approved in Australia

Ikaria Holdings, Inc., through its subsidiary INO Therapeutics LLC, announced today that it has received approval from Australia's regulatory body, the Therapeutic Goods Administration (TGA), for INOmax (nitric oxide) for inhalation.

27 Nov 2007

Europe to tackle brain disorder research by linking industry, academia

Attempts to cure brain-related disorders have proved less successful than therapies for other major conditions such as heart cancer, even though just as many people suffer from them.

27 Nov 2007

BioMarin files investigational NDA for PEG-PAL for the treatment of phenylketonuria

BioMarin Pharmaceutical Inc. has announced that it has filed an investigational new drug application (IND) with the U.S. Food and Drug Administration (FDA) for PEG-PAL (Poly Ethylene Glycol-Phenylalanine Ammonia Lyase), formerly known as Phenylase, for the treatment of phenylketonuria (PKU).

27 Nov 2007

Surge in HIV/AIDS prompts demand for all Beijing hotels to provide condoms

As a result of a surge in new HIV/AIDS cases in the first 10 months of this year, health authorities in China's capital Beijing have ordered all hotels in the city to provide condoms in every room.

27 Nov 2007

Wyeth receives European approval for TORISEL

Wyeth Pharmaceuticals, a division of Wyeth, has announced that the European Commission has approved TORISEL (temsirolimus) for the first-line treatment of patients with advanced renal cell carcinoma (RCC) who have at least three of six prognostic risk factors. TORISEL is the only approved cancer therapy that specifically inhibits the mTOR (mammalian target of rapamycin) kinase, an important regulator of cell proliferation, cell growth and cell survival.

27 Nov 2007

Isotechnika granted Norwegian patent for lead immunosuppressive drug

Isotechnika Inc. has announced that the Company has been issued Norwegian Patent No. 324042 for its lead immunosuppressive drug, ISA247.

27 Nov 2007

Deeper insights into the workings of the immune system

The first lines of defense in our immune systems are specialized mobile units that check the identity of cells to determine whether they are 'self' or 'foreign.'

27 Nov 2007

Novel proposal to overcome the virus sharing impasse

In light of the importance of virus monitoring for pandemic influenza preparedness and response, Indonesia's refusal to share samples of avian flu (H5N1) virus with the WHO for most of 2007 is "distressing and potentially dangerous for global public health," say two leading global health experts in an essay in this week's PLoS Medicine.

21 Nov 2007