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Young children experience better long-term kidney transplant success than adults, study finds

The success of kidney transplants has vastly improved for children over the past half-century, with young children now experiencing better long-term transplant success than adults, according to study results from a large pediatric transplant center.

27 Feb 2017

Researchers aim to develop sustained and controllable insulin release system for treatment of diabetes

The prevalence of diabetes has grown around the world over the past three decades. In 2016, the World Health Organization estimated that 422 million people had the disease as the rate of obesity also increased.

27 Feb 2017

$Study finds ketogenic diet as 'feasible' option for people with super-refractory status epilepticus$

Study finds ketogenic diet as 'feasible' option for people with super-refractory status epilepticus

In a small phase I and II clinical trial, Johns Hopkins researchers and colleagues elsewhere found that the high-fat, low-carbohydrate ketogenic diet was a safe and effective treatment option for the majority of adults experiencing a relatively rare, often fatal and always severe form of epilepsy marked by prolonged seizures that require medically induced comas to prevent them from further damaging the body and the brain.

27 Feb 2017

Hypoxia may be cause for seizure-related neuronal degeneration in epilepsy, study finds

Neuronal degeneration is the most severe long-term consequence of repetitive seizures in patients with epilepsy, which until now was thought to be primarily caused by excitotoxicity, or over-stimulation of the neurons.

27 Feb 2017

Study finds new mechanism underlying epileptic seizures

Prolonged epileptic seizures may cause serious problems that will continue for the rest of a patient's life. As a result of a seizure, neural connections of the brain may be rewired in an incorrect way.

27 Feb 2017

Universal public coverage of essential medicines could save over $4 billion per year, study finds

Universal public coverage of 117 essential medicines could address the needs of most Canadians for pharmaceutical drugs, and possibly save more than $4 billion a year, according to a new study published http://www.cmaj.ca/site/press/cmaj.161082.pdf in CMAJ.

27 Feb 2017

Researchers shed new light on molecular pump that ejects anticancer agents

Sometimes cells resist medication by spitting it back out. Cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs meant to kill them. Researchers at The Rockefeller University have shed new light on a molecular pump that makes this possible, by determining its three-dimensional structure, down to the level of atoms.

25 Feb 2017

Researchers discover promising target for treatment of leishmaniasis

Each year, about 2 million people contract leishmaniasis, a parasitic disease transmitted by the bite of a sand fly. The cutaneous form of the disease results in disfiguring skin ulcers that may take months or years to heal and in rare cases can become metastatic, causing major tissue damage.

24 Feb 2017

Novel antiviral drug can protect transplant patients against CMV infections

In a significant advance in improving the safety of donor stem cell transplants, a major clinical trial led by researchers at Dana-Farber Cancer Institute and Brigham and Women's Hospital has shown that a novel agent can protect against the most common viral infection that patients face after transplantation.

24 Feb 2017

New study finds huge problem of multi-drug resistant infections among children

In a new, first-of-its-kind study, researchers from Case Western Reserve University School of Medicine have found a 700-percent surge in infections caused by bacteria from the Enterobacteriaceae family resistant to multiple kinds of antibiotics among children in the US. These antibiotic resistant infections are in turn linked to longer hospital stays and potentially greater risk of death.

24 Feb 2017

New trial examines use of nanotechnology to improve delivery of drugs to HIV patients

Successful results of a University of Liverpool-led trial that utilised nanotechnology to improve drug therapies for HIV patients has been presented at the Conference on Retroviruses and Opportunistic Infections in Seattle, a leading annual conference of HIV research, clinical practice and progress.

24 Feb 2017

New investigational drug may help combat antibiotic-resistant global health threat

The deadly fungus, Candida auris, which has been found in hospitals, is resistant to entire classes of antimicrobial drugs, limiting treatment options for those infected.

24 Feb 2017

Researchers find link between low general cognitive ability and elevated risk of not taking statins

After a heart attack, it is important for patients to take medication that lowers cholesterol levels. In a new study published in the European Journal of Preventive Cardiology, researchers at Uppsala and Umeå Universities have found that general cognitive ability (intelligence) has a bearing, in the first year and two years after the heart attack, on how well men take statins prescribed for them.

24 Feb 2017

Newly discovered gene variants increase risk of anxiety disorders

Several newly discovered variants of a gene increase the risk of developing anxiety disorders. A research team aims to derive new therapies from this finding which are better tailored to the individual patients.

24 Feb 2017

Structure of unique amyloid fibrils could lead to discovery of new antibiotics

The highly pathogenic Staphylococcus aureus bacteria is one of the five most common causes of hospital-acquired infections. In the US alone, approximately 500,000 patients at hospitals contract a staph infection. It is the bacteria responsible for MRSA, for which there is no vaccine.

24 Feb 2017

Older people with back pain have 13% increased risk of dying from any cause, study finds

The 600,000 older Australians who suffer from back pain have a 13 per cent increased risk of dying from any cause, University of Sydney research has found.

24 Feb 2017

NR could potentially prevent chemotherapy-induced peripheral neuropathy in cancer patients

A new study in rats suggests that nicotinamide riboside (NR), a form of vitamin B3, may be useful for treating or preventing nerve pain (neuropathy) caused by chemotherapy drugs.

24 Feb 2017

Researchers develop new assay for measuring underlying autoimmunity in rheumatoid arthritis patients

Current treatments for rheumatoid arthritis relieve the inflammation that leads to joint destruction, but the immunologic defect that triggers the inflammation persists to cause relapses, according to research conducted at NYU Langone Medical Center and the University of Pittsburgh.

24 Feb 2017

New test could accelerate development of better treatments for Motor Neuron Disease

A cutting-edge test developed in South Australia has the potential to expedite the worldwide quest to develop better treatments, or even a cure, for the Motor Neuron Disease (MND).

24 Feb 2017

NSAIDs could potentially be repurposed as life-saving treatment for sepsis, research suggests

A potentially life-saving treatment for sepsis has been under our noses for decades in the non-steroidal anti-inflammatory drugs most people have in their medicine cabinets, a new University of Colorado Boulder study suggests.

23 Feb 2017

Drugs News and Research

Young children experience better long-term kidney transplant success than adults, study finds

Researchers aim to develop sustained and controllable insulin release system for treatment of diabetes

Study finds ketogenic diet as 'feasible' option for people with super-refractory status epilepticus

Hypoxia may be cause for seizure-related neuronal degeneration in epilepsy, study finds

Study finds new mechanism underlying epileptic seizures

Universal public coverage of essential medicines could save over $4 billion per year, study finds

Researchers shed new light on molecular pump that ejects anticancer agents

Researchers discover promising target for treatment of leishmaniasis

Novel antiviral drug can protect transplant patients against CMV infections

New study finds huge problem of multi-drug resistant infections among children

New trial examines use of nanotechnology to improve delivery of drugs to HIV patients

New investigational drug may help combat antibiotic-resistant global health threat

Researchers find link between low general cognitive ability and elevated risk of not taking statins

Newly discovered gene variants increase risk of anxiety disorders

Structure of unique amyloid fibrils could lead to discovery of new antibiotics

Older people with back pain have 13% increased risk of dying from any cause, study finds

NR could potentially prevent chemotherapy-induced peripheral neuropathy in cancer patients

Researchers develop new assay for measuring underlying autoimmunity in rheumatoid arthritis patients

New test could accelerate development of better treatments for Motor Neuron Disease

NSAIDs could potentially be repurposed as life-saving treatment for sepsis, research suggests

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