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Cerebellum can be responsible for brain alterations linked to drug addiction, research shows

An international research team led by the Universitat Jaume I has shown that the cerebellum, contrary to what was thought, fulfils functions that go beyond the motor sphere and can be co-responsible for the brain alterations associated with addictive consumption of drugs.

23 Feb 2017

New compounds with potent anticancer activity could lessen side effects of oncological treatments

The Universitat Jaume I, the Spanish Centre for Advanced Scientific Research and the University of Pavia have patented new compounds with potent anticancer activity in breast and colon tumour cell lines that have low toxicity in healthy cells, which can dramatically decrease side effects during chemotherapy treatment.

23 Feb 2017

Research reveals workings of ‘hidden code’ within genome of Human Parechovirus

Scientists at the Universities of York, Leeds, and Helsinki say they are a step closer to cracking, what researchers have dubbed, the 'Enigma Code' of the common cold virus.

23 Feb 2017

Mayo Clinic study finds link between biology of aging and idiopathic pulmonary fibrosis

A Mayo Clinic study has shown evidence linking the biology of aging with idiopathic pulmonary fibrosis, a disease that impairs lung function and causes shortness of breath, fatigue, declining quality of life, and, ultimately, death.

23 Feb 2017

Study identifies new role of cholesterol in regulating brain proteins

A study led by researchers at the Hospital del Mar Medical Research Institute and the Institute of Medical Physics and Biophysics at the Faculty of Medicine in Charité Hospital, Berlin, published in the journal Nature Communications, demonstrates that the cholesterol present in cell membranes can interfere with the function of an important brain membrane protein, through a previously unknown mode of interaction.

23 Feb 2017

Wastewater releases from oil and gas operations at West Virginia alter microbes, study finds

Wastewater from oil and gas operations -- including fracking for shale gas -- at a West Virginia site altered microbes downstream, according to a Rutgers-led study.

23 Feb 2017

Scientists create organ-on-a-chip that can mimic heart's biomechanical properties

The human heart beats more than 2.5 billion times in an average lifetime. Now scientists at Vanderbilt University have created a three-dimensional organ-on-a-chip that can mimic the heart's amazing biomechanical properties.

23 Feb 2017

Chemists discover cheaper, faster way to identify and test new drugs

Chemists at the University of Waterloo, SCIEX and Pfizer have discovered a new way to help the pharmaceutical industry identify and test new drugs, which could revolutionize drug development, and substantially reduce the cost and time drugs need to reach their market.

23 Feb 2017

BIDMC review focuses on neural circuitry of wakefulness and sleep

Sleep remains an enduring biological mystery with major clinical relevance, according to a review by clinician-researcher Thomas Scammell, MD, of Beth Israel Deaconess Medical Center (BIDMC) and colleagues.

23 Feb 2017

Researchers explore how G-protein-coupled receptors and arrestin form complexes

Researchers from Charité - Universitätsmedizin Berlin have been studying two proteins that play a vital role in many bodily processes.

23 Feb 2017

New research pinpoints how immigrant microbes get to the lungs

They traveled a huge distance, evaded a protective barrier, and found themselves in a strange and unwelcoming land.

23 Feb 2017

Study finds biochemical pathway that triggers regrowth of breast cancer stem cells after chemotherapy

Working with human breast cancer cells and mice, researchers at Johns Hopkins say they have identified a biochemical pathway that triggers the regrowth of breast cancer stem cells after chemotherapy.

22 Feb 2017

Scientists discover potent trigger of inflammatory disease

Institute scientists have revealed a potent inflammatory molecule released by dying cells triggers inflammation during necroptosis, a recently described form of cell death linked to inflammatory disease.

22 Feb 2017

Scientists detect antimicrobial protein fragments in Komodo dragon’s blood

In a land where survival is precarious, Komodo dragons thrive despite being exposed to scads of bacteria that would kill less hardy creatures.

22 Feb 2017

Brain scans could improve prediction of problem drug use among teenagers

There's an idea out there of what a drug-addled teen is supposed to look like: impulsive, unconscientious, smart, perhaps - but not the most engaged. While personality traits like that could signal danger, not every adolescent who fits that description becomes a problem drug user. So how do you tell who's who?

22 Feb 2017

New compound kills whipworm more effectively than existing drugs

The human whipworm, which infects 500 million people and can damage physical and mental growth, is killed at egg and adult stage by a new drug class developed at the Universities of Manchester and Oxford and University College London.

From The University of Manchester 22 Feb 2017

Researchers develop new tool to help avoid adverse reactions to drugs

Researchers at the University of Liverpool, Alder Hey, University of Central Lancashire and University College London have developed a new tool to help avoid adverse reactions to medicines.

22 Feb 2017

Prolonged use of popular heartburn drugs linked to silent, gradual kidney damage

Taking popular heartburn drugs for prolonged periods has been linked to serious kidney problems, including kidney failure.

22 Feb 2017

Drugs that target tissue stiffness could potentially prevent cancer metastasis

In order for cancer to spread, malignant cells must break away from a tumor and through the tough netting of extracellular matrix, or ECM, that surrounds it. To fit through the holes in this net, those cancerous cells must elongate into a torpedo-like shape.

22 Feb 2017

Mouse model shows how chronic demyelination may cause seizures in MS patients

Multiple sclerosis is an autoimmune disease of the central nervous system that affects nearly 2.3 million people worldwide.

22 Feb 2017

Drugs News and Research

Cerebellum can be responsible for brain alterations linked to drug addiction, research shows

New compounds with potent anticancer activity could lessen side effects of oncological treatments

Research reveals workings of ‘hidden code’ within genome of Human Parechovirus

Mayo Clinic study finds link between biology of aging and idiopathic pulmonary fibrosis

Study identifies new role of cholesterol in regulating brain proteins

Wastewater releases from oil and gas operations at West Virginia alter microbes, study finds

Scientists create organ-on-a-chip that can mimic heart's biomechanical properties

Chemists discover cheaper, faster way to identify and test new drugs

BIDMC review focuses on neural circuitry of wakefulness and sleep

Researchers explore how G-protein-coupled receptors and arrestin form complexes

New research pinpoints how immigrant microbes get to the lungs

Study finds biochemical pathway that triggers regrowth of breast cancer stem cells after chemotherapy

Scientists discover potent trigger of inflammatory disease

Scientists detect antimicrobial protein fragments in Komodo dragon’s blood

Brain scans could improve prediction of problem drug use among teenagers

New compound kills whipworm more effectively than existing drugs

Researchers develop new tool to help avoid adverse reactions to drugs

Prolonged use of popular heartburn drugs linked to silent, gradual kidney damage

Drugs that target tissue stiffness could potentially prevent cancer metastasis

Mouse model shows how chronic demyelination may cause seizures in MS patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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