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Study finds different DNA alterations in tumor genomes of smokers and never-smokers

Lung tumors in those who smoke and those who never smoked have different DNA alterations in the tumor genomes, according to results of a pilot study presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held Nov. 7-10, 2010, in Philadelphia.

10 Nov 2010

Long-term use of statins unlikely to substantially increase overall cancer risk: Study

Researchers have further established that long-term use of statins is unlikely to substantially increase or decrease overall cancer risk, according to study results presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held Nov. 7-10, 2010, in Philadelphia.

10 Nov 2010

Data shows hormone therapy can increase risk of ovarian cancer

Women planning on taking hormone therapy for the treatment of menopausal symptoms should be aware of a possible increased risk for ovarian cancer, according to data presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held here Nov. 7-10, 2010.

10 Nov 2010

Aromatase inhibitors increase side effects in women undergoing breast cancer therapy

Women being treated for breast cancer with aromatase inhibitors may experience extremely low estrogen levels resulting in a wide variety of side effects that a typical postmenopausal woman without cancer may not experience.

10 Nov 2010

Only one-third of young women complete HPV regimen

Despite strong evidence of its effectiveness, few of the young women who are eligible for the human papillomavirus (HPV) vaccine take it, according to research presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held Nov. 7-10.

10 Nov 2010

Affluent people face higher risk of melanoma

According to scientists at the Cancer Prevention Institute of California (CPIC), affluent people are at a much higher risk of melanoma than the rest of the population of whites in California.

10 Nov 2010

Home smoking restrictions needed to reduce tobacco-related carcinogens in children's urine

Ninety percent of children who lived in a house where an adult smoked had evidence of tobacco-related carcinogens in their urine, according to research presented at the Ninth AACR Frontiers in Cancer Prevention Research Conference, held here from Nov 7-10, 2010.

10 Nov 2010

Physical activity lowers risk of endometrial cancer

Women who exercise for 150 minutes a week or more may see a reduced risk of endometrial cancer, despite whether or not they are overweight, according to data presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held here Nov. 7-10, 2010.

10 Nov 2010

$Long-term androgen deprivation therapy increases risk of fracture in older men with prostate cancer$

Long-term androgen deprivation therapy increases risk of fracture in older men with prostate cancer

Men with history of fracture and comorbidities are at an increased risk of fracture after long-term use of androgen deprivation therapy, and initiating this therapy should be carefully considered in older men with localized prostate cancer.

9 Nov 2010

Blood 'metabolomics' study uncovers liver, heart, and kidney toxicity in healthy smokers

Examining the blood "metabolomics" profile of smokers immediately after they had a cigarette revealed activation of pathways involved in cell death, inflammation, and other forms of systemic damage, say researchers at Georgetown Lombardi Comprehensive Cancer Center, part of Georgetown University Medical Center.

9 Nov 2010

S.A.N.E. Vax calls for federal approval of reliable HPV genotyping test in cervical cancer prevention programs

In a letter addressed to Dr. Harold E. Varmus, director of the NCI, and Dr. Margaret Hamburg, FDA commissioner, Ms. Norma Erickson, president of S.A.N.E. Vax, Inc., requested that these two federal agencies recommend a reliable human papillomavirus (HPV) genotyping test to support the national virology-based cervical cancer prevention program for patient care. Erickson stated: "The NCI knows reliable HPV genotyping is based on using a PCR system with short target sequencing."

9 Nov 2010

Gefitinib exhibits potential as chemoprevention agent for pancreatic cancer

Gefitinib may be a promising chemoprevention agent for pancreatic cancer, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

9 Nov 2010

Smoking increases risk of breast cancer progression in multiethnic women with breast cancer

Being a current smoker or having a history of smoking significantly increased the risk of breast cancer progression and overall death among a group of multiethnic women with breast cancer, according to the results of a large prospective cohort study.

9 Nov 2010

Statins do not reduce risk for colorectal cancer in postmenopausal women

The use of statins among a group of postmenopausal women did not reduce the risk for colorectal cancer, according to the results of a prospective analysis of data from the large population-based Women's Health Initiative (WHI).

9 Nov 2010

Obesity does not increase breast cancer risk in Mexican-American women: Research

Obesity was not associated with breast cancer risk in Mexican-American women, even when measured at numerous ages throughout a woman's lifetime, according to data presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held here Nov. 7-10, 2010.

8 Nov 2010

Study finds anti-gout medication may reduce risk of colorectal cancer

Allopurinol, a relatively inexpensive anti-gout medication that has been on the market for more than 20 years, may have some activity against colorectal adenomas, according to data presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held here Nov. 7-10, 2010.

8 Nov 2010

Potential biomarker for measuring progress in breast cancer chemoprevention trials

Researchers at Duke University Medical Center have identified a possible biomarker for measuring progress in breast cancer chemoprevention trials, according to data presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held here Nov. 7-10, 2010.

8 Nov 2010

Soy-based drug could prevent prostate cancer metastasis

Northwestern Medicine researchers at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University have found that a new, nontoxic drug made from a chemical in soy could prevent the movement of cancer cells from the prostate to the rest of the body.

8 Nov 2010

Soy isoflavone intake decreases risk of invasive breast tumor

Increased phytoestrogens commonly found in dietary soy may modify the risk of some types of breast cancer, according to findings presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held Nov. 7-10, 2010.

8 Nov 2010

Prolonged separation from mother increases risk of breast cancer in young mice

Young mice that experienced the psychosocial stress of prolonged separation from their mothers had a higher incidence and faster onset of breast tumors compared with young mice who did not experience this stressful life event. Specifically, neonatal mice separated from their mothers for a prolonged period of time developed mammary tumors twice as fast as mice that experienced short or no maternal separation.

8 Nov 2010

Cancer Prevention News and Research

Study finds different DNA alterations in tumor genomes of smokers and never-smokers

Long-term use of statins unlikely to substantially increase overall cancer risk: Study

Data shows hormone therapy can increase risk of ovarian cancer

Aromatase inhibitors increase side effects in women undergoing breast cancer therapy

Only one-third of young women complete HPV regimen

Affluent people face higher risk of melanoma

Home smoking restrictions needed to reduce tobacco-related carcinogens in children's urine

Physical activity lowers risk of endometrial cancer

Long-term androgen deprivation therapy increases risk of fracture in older men with prostate cancer

Blood 'metabolomics' study uncovers liver, heart, and kidney toxicity in healthy smokers

S.A.N.E. Vax calls for federal approval of reliable HPV genotyping test in cervical cancer prevention programs

Gefitinib exhibits potential as chemoprevention agent for pancreatic cancer

Smoking increases risk of breast cancer progression in multiethnic women with breast cancer

Statins do not reduce risk for colorectal cancer in postmenopausal women

Obesity does not increase breast cancer risk in Mexican-American women: Research

Study finds anti-gout medication may reduce risk of colorectal cancer

Potential biomarker for measuring progress in breast cancer chemoprevention trials

Soy-based drug could prevent prostate cancer metastasis

Soy isoflavone intake decreases risk of invasive breast tumor

Prolonged separation from mother increases risk of breast cancer in young mice

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