Immune Response News and Research

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Study suggests the rapid expansion of naïve T cells can provide a fast and effective immune response to SARS-CoV-2 and other viral infections

Researchers investigated the early T cell responses during SARS-CoV-2 infections to understand the mechanisms of rapid clonal expansion that characterize the T cell responses to acute infections and vaccinations.

14 Nov 2022

What is the role of macrophage origin, function, and heterogeneity in health and disease?

In a new study, researchers examined the wealth of information available regarding the heterogeneity of tissue macrophages.

14 Nov 2022

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Researchers investigated the change in the stability, antigenicity, and protein expression of the SARS-CoV-2 spike protein trimer using structure-directed mutagenesis to alter a cavity in the core of the spike protein.

14 Nov 2022

How mRNA vaccines work without an added adjuvant

In a recent study published in the Immunity journal, researchers explored the current knowledge of the mechanism employed by messenger ribonucleic acid (mRNA) vaccines to elicit innate immune activation.

13 Nov 2022

Researchers receive NIH grant to develop mRNA vaccines to deter cancer development

A multidisciplinary team of Weill Cornell Medicine researchers have received a five-year $5.7 million grant from the National Cancer Institute at the National Institutes of Health to fund a center aimed at developing messenger RNA (mRNA) vaccines to deter cancer development in at-risk groups.

11 Nov 2022

Nanotechnology platform can make solid tumor cells more receptive to immunotherapy

A team of researchers at The University of Texas MD Anderson Cancer Center has developed a nanotechnology platform that can change the way the immune system sees solid tumor cells, making them more receptive to immunotherapy.

10 Nov 2022

Experimental therapeutic cancer vaccine leads to significant tumor regression in mice

An experimental therapeutic cancer vaccine induced two distinct and desirable immune system responses that led to significant tumor regression in mice, report investigators from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

10 Nov 2022

The roles of innate and adaptive immunity in Alzheimer’s disease development and progression

Researchers reviewed research advancements showing the significant role both innate and adaptive immune systems play in the pathological course of Alzheimer’s disease.

10 Nov 2022

Irish Government funds tripartite collaboration to explore the role of vitamin D in bovine TB

The Irish Government has funded a tripartite collaboration to investigate the role of vitamin D in bovine tuberculosis (bTB).

10 Nov 2022

COVID-19 vaccination provides higher concentrations of antibodies to babies and pregnant people

Pregnant people who received one of the mRNA COVID-19 vaccines had 10-fold higher antibody concentrations than those who were naturally infected with SARS-CoV-2, a finding that was also observed in their babies, according to a new study by researchers at Children's Hospital of Philadelphia and the University of Pennsylvania.

9 Nov 2022

Scientists create an atlas of liver infection caused by Plasmodium parasites

Malaria is a devastating disease caused by the Plasmodium parasite. After an infected mosquitos' bite, the parasites travel to the liver and infect liver cells.

9 Nov 2022

Immunological responses against monkeypox virus concerning the 2022 outbreak

A new study aimed to analyze the kinetics of the pox-specific T-cell induction, the inflammatory profile, and the inflammatory profile in human cases of the current monkeypox outbreak.

9 Nov 2022

Researchers propose a deep antibody-antigen interaction algorithm to accelerate the identification of potential therapeutic antibodies

Researchers used a deep antibody-antigen interaction (DeepAAI) algorithm to understand the antibody representations of unseen antibodies to accelerate the discovery of novel antibodies with potential therapeutic applications.

9 Nov 2022

What is the role of adenoviruses in human health?

With advances in molecular biology informing recent developments in vaccinology, gene therapy, and other fields of medicine, human adenoviruses (HAdVs) have been of primary importance in medical research. A recent review looks at the promises of HAdVs, their potential dangers, and future challenges.

9 Nov 2022

Study helps understand the basis of sex differences in SARS-CoV-2 infection

Significant immunological differences between young men and women were shown to mediate sex differences in the responses to the virus that causes COVID-19, according to a collaborative study of nearly 3,000 young, healthy members of the U.S. Marine Corps.

8 Nov 2022

Higher dose of pneumococcal vaccine improves antibody response in patients receiving rituximab for ANCA-associated vasculitis

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, showed that a higher dose of pneumococcal vaccine safely and effectively improved antibody response in patients receiving rituximab for ANCA-associated vasculitis.

8 Nov 2022

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

In a recent study published in the journal Cell Host & Microbe, researchers pursued novel approaches that could help find monoclonal antibodies (mAbs) broadly targeting coronaviruses (CoVs), especially genera beta CoVs.

8 Nov 2022

Cancer drugs work better after vaccination with the Chinese Covid vaccine

Patients with nasopharyngeal cancer are often treated with drugs that activate their immune system against the tumor.

8 Nov 2022

Does vitamin D reduce COVID-19 severity?

A new study examined published studies for a consistent association between vitamin D levels and coronavirus disease 2019 (COVID-19) severity.

8 Nov 2022

Children exposed to air pollution in early years more likely to develop food allergies

A new research paper explores associations between food allergies and pre- or post-natal exposure to pollutants in the air, thus paving the way for future studies on the potential sensitization of the gut by exposure of the skin or airway to pollutants, in addition to the alimentary route.

7 Nov 2022

Immune Response News and Research

Study suggests the rapid expansion of naïve T cells can provide a fast and effective immune response to SARS-CoV-2 and other viral infections

What is the role of macrophage origin, function, and heterogeneity in health and disease?

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

How mRNA vaccines work without an added adjuvant

Researchers receive NIH grant to develop mRNA vaccines to deter cancer development

Nanotechnology platform can make solid tumor cells more receptive to immunotherapy

Experimental therapeutic cancer vaccine leads to significant tumor regression in mice

The roles of innate and adaptive immunity in Alzheimer’s disease development and progression

Irish Government funds tripartite collaboration to explore the role of vitamin D in bovine TB

COVID-19 vaccination provides higher concentrations of antibodies to babies and pregnant people

Scientists create an atlas of liver infection caused by Plasmodium parasites

Immunological responses against monkeypox virus concerning the 2022 outbreak

Researchers propose a deep antibody-antigen interaction algorithm to accelerate the identification of potential therapeutic antibodies

What is the role of adenoviruses in human health?

Study helps understand the basis of sex differences in SARS-CoV-2 infection

Higher dose of pneumococcal vaccine improves antibody response in patients receiving rituximab for ANCA-associated vasculitis

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

Cancer drugs work better after vaccination with the Chinese Covid vaccine

Does vitamin D reduce COVID-19 severity?

Children exposed to air pollution in early years more likely to develop food allergies

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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