Pathogen News and Research

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A new approach to estimate the risks of exposure to COVID-19 under different indoor settings

Two MIT professors have proposed a new approach to estimating the risks of exposure to Covid-19 under different indoor settings.

16 Apr 2021

Study: Norovirus clusters are resistant to detergent and ultraviolet disinfection

Clusters of a virus known to cause stomach flu are resistant to detergent and ultraviolet disinfection, according to new research co-led by Danmeng Shuai, Ph.D., an associate professor of civil and environmental engineering at the George Washington University and Nihal Altan-Bonnet, Ph.D., a senior investigator and the head of the Laboratory of Host-Pathogen Dynamics at the National Heart, Lung, and Blood Institute, part of the National Institutes of Health.

16 Apr 2021

UGA receives NIH contract to establish the Center for Influenza Disease and Emergence Research

The National Institutes of Health has awarded the University of Georgia a contract to establish the Center for Influenza Disease and Emergence Research.

15 Apr 2021

New plasmonic isothermal PCR technology can detect respiratory viral pathogens in 30 minutes

Researchers in South Korea developed a plasmonic isothermal recombinase polymerase amplification (RPA) array chip, the world's first plasmoinc isothermal PCR technology which can detect 8 types of pathogens (4 bacteria and 4 viruses) that cause acute respiratory infectious diseases in 30 minutes.

15 Apr 2021

Researchers unravel the molecular basis of how Mtb uses and transports an essential sugar

Tuberculosis is a devastating disease that claims over 1.5 million lives each year. The increase in TB cases that are resistant to the current antibiotics means that novel drugs to kill Mycobacterium tuberculosis (Mtb) are urgently needed.

15 Apr 2021

Study observes neurological and psychiatric outcomes in recovered COVID-19 patients six months post-infection

A new study by researchers at Oxford University examines neurological and psychiatric outcomes in recovered COVID-19 patients six months post-infection.

15 Apr 2021

Allometric model shows human travel is closely related to spread of COVID-19

A new study indicates that the spread of COVID-19 is governed by power-law dynamics, suggesting that alternative modeling approaches need to be used to understand and predict its propagation.

15 Apr 2021

Self-assembling nanofibers can help limit damage caused by inflammatory diseases

Biomedical engineers at Duke University have developed a self-assembling nanomaterial that can help limit damage caused by inflammatory diseases by activating key cells in the immune system.

15 Apr 2021

SARS-CoV-2 variants are widely spread across the Houston metropolitan area

In late 2020, several concerning SARS-CoV-2 variants emerged globally. They are believed to be more easily transmissible, and there is concern that some may reduce the effectiveness of antibody treatments and vaccines.

14 Apr 2021

A new polymersome-based SARS-CoV-2 nanovaccine elicits robust immunity

As newer vaccines are being developed to combat the ongoing pandemic of coronavirus disease 2019 (COVID-19), targeting the pathogen, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a new preprint research paper posted to the bioRxiv server describes a new subunit nanovaccine that appears to have robust immunogenicity and neutralizing activity.

14 Apr 2021

Could cow's milk provide some passive immunity against COVID-19?

Researchers at the Department of Animal Health, University of Cordoba, Córdoba, Spain, speculate that bovine milk consumption – specifically from cows with resistance to bovine coronaviruses – may potentially provide at least some degree of protection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The article is available to read in full on the Frontiers in Immunology website.

13 Apr 2021

Researchers develop broad-spectrum SARS-CoV-2 RBD-based vaccine

In a recent bioRxiv* preprint, the large team of researchers evaluated a SARS-CoV-2 Spike receptor-binding domain ferritin nanoparticle protein vaccine (RFN) in a nonhuman primate challenge model. This study addresses the need for a next-generation, efficacious vaccine with an increased pan-SARS breadth of coverage.

13 Apr 2021

Researchers identify SARS-CoV-2 antiviral compounds using protein assay

During the process of SARS-CoV-2 infection, once the virus penetrates the host cell, two open reading frames, ORF1a and ORF1ab, are translated. ORF1ab is responsible for the production of 16 nonstructural proteins (nsp). Several viral proteases such as 3CLpro and PLpro (papain-like protease) produce 1-16 nsps. A new study has been published in bioRxiv* preprint server, which deals with identifying drugs that are effective as PLpro inhibitors.

13 Apr 2021

Monitoring CO2 to assess risk of indoor airborne SARS-CoV-2 transmission

In the study, which appeared on the pre-print server medRxiv, the team developed a general mathematical theory to predict airborne transmission risk from carbon dioxide (CO2) time series in real-time and clarify different estimates that steer the guideline. The study findings were based on the assessment of transmission risk and implementing the guideline by CO2 monitoring in university classrooms and office spaces.

13 Apr 2021

Researchers provide ultrastructural details of SARS-CoV-2-infected respiratory epithelial cells

A team of scientists from the United Kingdom recently investigated the ultrastructural details of the attachment, entry, and budding processes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the human airway epithelium. They have used a highly differentiated air-liquid interface cultures of airway epithelium to thoroughly investigate the viral infection cycle. The study is currently available on the bioRxiv* preprint server.

12 Apr 2021

SARS-CoV-2 spike E484K mutation reduces antibody neutralization

Researchers at the Department of Microbiology, Icahn School of Medicine at Mount Sinai New York, USA, showed that the SARS-CoV-2 spike E484K mutation reduces antibody neutralization.

12 Apr 2021

Does natural infection with SARS-CoV-2 offer more protection than a vaccine against new variants?

A new study demonstrates that vaccines may be less effective at countering the newer SARS-CoV-2 variants compared to natural infection.

9 Apr 2021

Novel protein transport system mediates toxin secretion by tuberculosis pathogen

Six years ago, Michael Niederweis, Ph.D., described the first toxin ever found for the deadly pathogen Mycobacterium tuberculosis.

9 Apr 2021

Purdue researchers use malaria expertise to track COVID-19 in Indiana

Scientists have been using genetics to track diseases for decades. Now, a team at Purdue University that typically tracks malaria spread in Southern and Central Africa is using its expertise to track COVID-19 in Indiana.

8 Apr 2021

Thermo Fisher Scientific launches in-air SARS-CoV-2 surveillance solution

Thermo Fisher Scientific Inc., the world leader in serving science, today announced the launch of the Thermo Scientific AerosolSense Sampler, a new surveillance solution designed to deliver fast and highly reliable insight into the presence of in-air pathogens, including SARS-CoV-2.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 8 Apr 2021

Pathogen News and Research

A new approach to estimate the risks of exposure to COVID-19 under different indoor settings

Study: Norovirus clusters are resistant to detergent and ultraviolet disinfection

UGA receives NIH contract to establish the Center for Influenza Disease and Emergence Research

New plasmonic isothermal PCR technology can detect respiratory viral pathogens in 30 minutes

Researchers unravel the molecular basis of how Mtb uses and transports an essential sugar

Study observes neurological and psychiatric outcomes in recovered COVID-19 patients six months post-infection

Allometric model shows human travel is closely related to spread of COVID-19

Self-assembling nanofibers can help limit damage caused by inflammatory diseases

SARS-CoV-2 variants are widely spread across the Houston metropolitan area

A new polymersome-based SARS-CoV-2 nanovaccine elicits robust immunity

Could cow's milk provide some passive immunity against COVID-19?

Researchers develop broad-spectrum SARS-CoV-2 RBD-based vaccine

Researchers identify SARS-CoV-2 antiviral compounds using protein assay

Monitoring CO2 to assess risk of indoor airborne SARS-CoV-2 transmission

Researchers provide ultrastructural details of SARS-CoV-2-infected respiratory epithelial cells

SARS-CoV-2 spike E484K mutation reduces antibody neutralization

Does natural infection with SARS-CoV-2 offer more protection than a vaccine against new variants?

Novel protein transport system mediates toxin secretion by tuberculosis pathogen

Purdue researchers use malaria expertise to track COVID-19 in Indiana

Thermo Fisher Scientific launches in-air SARS-CoV-2 surveillance solution

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