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Researchers identify new unexpected cause for hidden hearing loss

Patients who complain they can't hear their friends at a noisy restaurant, but pass a hearing test in their doctor's office, may be describing hidden hearing loss.

20 Feb 2017

Genomic analysis of brain tumor helps doctors keep cancer at bay for five years

An analysis of a patient's deadly brain tumor helped doctors at Smilow Cancer Hospital identify new emerging mutations and keep a 55-year old woman alive for more than five years, researchers report in the journal Genome Medicine.

17 Feb 2017

Disappointing Merck drug news provides new blueprint for moving towards cure for Alzheimer's

The recent announcement that Merck is halting a Phase II/III study for a promising Alzheimer's treatment (verubecestat) was another setback in the continued and intensive effort to deliver an innovative therapy by 2020.

17 Feb 2017

New approach could make organometallic catalysis applicable for therapy or diagnostics

A gold catalyst can be delivered to a target organ in a higher organism where it performs a chemical transformation visualized by bioimaging.

17 Feb 2017

UC San Diego researchers receive new grant to advance malaria research

An international research team, led by principal investigator Elizabeth A. Winzeler, PhD, professor in the pediatric division of host-microbe systems and therapeutics at University of California San Diego School of Medicine, and colleagues have received a three-year, $4.7 million supplemental grant from the Bill & Melinda Gates Foundation to advance their development of improved therapies for malaria eradication and elimination.

17 Feb 2017

New article provides thought-provoking view on the rise of allergy, autoimmune diseases

This new feature article by Megan Scudellari is a well-researched, thought provoking view on the rise of allergy and autoimmune diseases and shows how, if looked at objectively, it’s obviously due to “much more than rampant cleanliness”.

17 Feb 2017

DNA computer could be important step towards development of smart, 'intelligent' drugs

Researchers at Eindhoven University of Technology present a new method that should enable controlled drug delivery into the bloodstream using DNA computers.

17 Feb 2017

MDI Biological Laboratory scientist sheds light on molecular mechanisms underlying aging

Scientists have known for decades that drastically restricting certain nutrients without causing malnutrition prolongs health and lifespan in a wide range of species, but the molecular mechanisms underlying this effect have remained a mystery.

17 Feb 2017

Scientists map vast spider web of cancer proteins to reveal new drug targets

Scientists at Winship Cancer Institute of Emory University have mapped a vast spider web of interactions between proteins in lung cancer cells, as part of an effort to reach what was considered "undruggable."

17 Feb 2017

New method that detects NMD efficiency could help in treatment of many diseases

In cells, DNA is first converted to RNA, and RNA is next converted to proteins--a complicated process involving several other steps. Nonsense-mediated RNA decay is a processing pathway in cells that, like a broom, cleans up erroneous RNA to prevent its productive conversion into an aberrant protein, which could lead to disease.

17 Feb 2017

Experts outline new methodologies that may lead to individualized patient care

In the current issue of Psychotherapy and Psychosomatic Dr. Ralph Horwitz and colleagues outline new methodologies, in addition to the well-known randomized controlled trials, to gather information that may lead to individualized patient care.

16 Feb 2017

SLU scientist examines potential biomarkers for pain linked to debilitating health conditions

With new funding from The Mayday Fund, a Saint Louis University researcher will leverage her discovery of a pain pathway to determine if either of two key molecules can be used as biomarkers for pain associated with four debilitating health conditions: chemotherapy-induced peripheral neuropathy, endometriosis, interstitial cystitis and vulvodynia.

16 Feb 2017

Doctors use targeted molecular drugs to treat fatal cancerous blood syndromes

Genomic testing of biopsies from patients with deadly, treatment-resistant cancerous blood syndromes called histiocytoses allowed doctors to identify genes fueling the ailments and use targeted molecular drugs to successfully treat them.

16 Feb 2017

HMS scientists listen to crosstalk between gut microbes and immune system

The human gut is home to some 100 trillion bacteria, comprising between 250 and 500 species. This astounding array of organisms, collectively known as the gut microbiome, is a powerful regulator of disease and health and has been implicated in conditions ranging from inflammatory bowel disease to multiple sclerosis.

16 Feb 2017

Weak working memory and impulse control pose serious risk for later substance abuse in adolescents

Drug use in adolescence is often linked to later substance-abuse problems, but a new study suggests that a key risk factor is a combination of weak working memory and difficulties with impulse control.

16 Feb 2017

Clinical trial to test potential new drug treatment for osteoarthritis

The University of Liverpool, in partnership with AKL Research and Development Ltd, is to lead on a clinical trial to test a potential new drug treatment for osteoarthritis.

16 Feb 2017

UMass Amherst study highlights unmet drug needs of patients with rare diseases

A new analysis by health policy researchers at the University of Massachusetts Amherst who studied the effectiveness of the 1983 Orphan Drug Act finds that current incentives "are not sufficiently stimulating orphan drug development" by pharmaceutical companies, and patients with rare diseases and conditions still have unmet needs. Further, barriers to ethical and timely access remain.

16 Feb 2017

Drugs News and Research

Researchers identify new unexpected cause for hidden hearing loss

Genomic analysis of brain tumor helps doctors keep cancer at bay for five years

Disappointing Merck drug news provides new blueprint for moving towards cure for Alzheimer's

New approach could make organometallic catalysis applicable for therapy or diagnostics

UC San Diego researchers receive new grant to advance malaria research

New article provides thought-provoking view on the rise of allergy, autoimmune diseases

DNA computer could be important step towards development of smart, 'intelligent' drugs

MDI Biological Laboratory scientist sheds light on molecular mechanisms underlying aging

Scientists map vast spider web of cancer proteins to reveal new drug targets

New method that detects NMD efficiency could help in treatment of many diseases

Experts outline new methodologies that may lead to individualized patient care

SLU scientist examines potential biomarkers for pain linked to debilitating health conditions

Doctors use targeted molecular drugs to treat fatal cancerous blood syndromes

HMS scientists listen to crosstalk between gut microbes and immune system

Weak working memory and impulse control pose serious risk for later substance abuse in adolescents

Clinical trial to test potential new drug treatment for osteoarthritis

UMass Amherst study highlights unmet drug needs of patients with rare diseases

High-dose B vitamins can effectively reduce schizophrenia symptoms, research finds

Paxman's scalp cooling system shows to successfully reduce alopecia during chemotherapy in breast cancer patients

IDSA guidelines: Team approach vital to successful treatment of complex neurological infections

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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