Chronic News and Research

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Simvastatin may slow progression of multiple sclerosis

Results of a phase 2 study published in The Lancet suggest that simvastatin, a cheap cholesterol lowering drug, might be a potential treatment option for the secondary progressive, or chronic, stage of multiple sclerosis (MS), which is currently untreatable.

20 Mar 2014

VaxInnate starts Phase 1 clinical trial to evaluate VAX2012Q for prevention of seasonal influenza

VaxInnate Corporation today announced that enrollment has commenced in a Phase 1 clinical trial to evaluate VAX2012Q, a recombinant quadrivalent vaccine in development for the prevention of seasonal influenza. VaxInnate is a biotechnology firm pioneering a breakthrough technology platform for the development of novel vaccines.

20 Mar 2014

Novel feedback provides mechanistic link between chronic inflammation and carcinogenesis

Researchers of Ludwig-Maximilians-Universitaet (LMU) in Munich have discovered a novel feedback mechanism that provides a mechanistic link between chronic inflammation and carcinogenesis.

20 Mar 2014

Preterm babies' guts harbor infectious microbes that can cause late-onset sepsis

Babies born prematurely are surviving in increasing numbers. But many withstand complications of early birth only to suffer late-onset sepsis - life-threatening bloodstream infections that strike after infants reach 72 hours of age.

20 Mar 2014

New drug for patients with leukaemia and lymphoma puts an end to chemotherapy

Patients with terminal forms of leukaemia and lymphoma who have run out of treatment options could soon benefit from a new drug, which not only puts an end to chemotherapy and has virtually no side effects but also improves a patient's life expectancy and quality of life.

20 Mar 2014

CLL patients more prone to infections due to reduced number of antibodies

People with chronic lymphocytic leukaemia (CLL) are essentially more prone to infections such as varicella, influenza or pneumococci due to the reduction in the number of antibodies that their condition causes.

19 Mar 2014

Biologists discover WBC moves to inflamed sites by walking in a stepwise manner

A team of biologists and engineers at the University of California, San Diego has discovered that white blood cells, which repair damaged tissue as part of the body's immune response, move to inflamed sites by walking in a stepwise manner.

19 Mar 2014

COPD in older adults linked with increased risk for mild cognitive impairment

A diagnosis of chronic obstructive pulmonary disease (COPD) in older adults was associated with increased risk for mild cognitive impairment (MCI), especially MCI of skills other than memory, and the greatest risk was among patients who had COPD for more than five years.

19 Mar 2014

Medivir announces phase III ATTAIN study of simeprevir inhibitor in treatment of adult patients with HCV

Medivir AB today announced that new phase III data for the once-daily protease inhibitor simeprevir have been presented at the Conference of the Asian Pacific Association for the Study of the Liver (APASL) in Brisbane, Australia.

19 Mar 2014

Study: Three-fold spike in heart attacks continued six years after Hurricane Katrina

Lingering stress from major disasters can damage health years later, according to a new Tulane University study that found a three-fold spike in heart attacks continued in New Orleans six years after Hurricane Katrina.

19 Mar 2014

Higher genetic risk of obesity may amplify effects of fried food consumption on body weight

People with a genetic predisposition to obesity are at a higher risk of obesity and related chronic diseases from eating fried foods than those with a lower genetic risk, according to a new study from researchers from Harvard School of Public Health, Brigham and Women's Hospital, and Harvard Medical School.

19 Mar 2014

Computer analysis of various subtypes of asthma could eventually lead to improved therapy, says study

So many variables can contribute to shortness of breath that no person can keep them all straight. But a computer program, capable of tracking more than 100 clinical variables for almost 400 people, has shown it can identify various subtypes of asthma, which perhaps could lead to targeted, more effective treatments.

19 Mar 2014

Kessler Foundation receives grant to supports variety of rehabilitation research projects in spinal cord injury

Kessler Foundation has received more than $718,000 in grant funding from the Craig Neilsen Foundation. The funding, comprised of five grants, supports a variety of rehabilitation research projects in spinal cord injury (SCI), including pain management, functional outcomes, quality of life, and factors affecting cognitive function.

18 Mar 2014

Body clock's could be utilized to improve current therapies to delay onset of chronic lung diseases

The body clock's natural rhythm could be utilized to improve current therapies to delay the onset of chronic lung diseases.

From The University of Manchester 18 Mar 2014

Non-alcoholic steatohepatitis (NASH): an interview with Jean-François Mouney, CEO of Genfit

The progressive form of Non-Alcoholic Fatty Liver Disease (NAFLD) is Non-Alcoholic Steatohepatitis (NASH), which defines a subgroup of NAFLD where liver steatosis co-exists with cell injury (hepatocyte ballooning) and inflammation with or without fibrosis at histological examination.

18 Mar 2014

New standard for U.S. heart transplantation

The Cedars-Sinai Heart Institute has set a new standard for U.S. heart transplantation by completing 117 adult heart transplants and two adult heart-lung transplants, for a total of 119 adult heart transplants in a single year. The previous number set in 2005, was 98 adult heart transplants performed in one year.

18 Mar 2014

Improving coordination of care for elderly patients trims costs and complications

Improving the coordination of care for elderly patients with chronic diseases trims costs, reduces use of health services and cuts complications, according to a new RAND Corporation study.

18 Mar 2014

ATS develops clinical practice guidelines to help clinicians identify, manage patients with sickle cell disease

The American Thoracic Society has developed clinical practice guidelines to help clinicians identify and manage patients with sickle cell disease who are at increased risk for mortality from pulmonary hypertension.

18 Mar 2014

People who experience chronic sleep disturbance could face earlier onset of dementia, Alzheimer's

People who experience chronic sleep disturbance—either through their work, insomnia or other reasons—could face an earlier onset of dementia and Alzheimer's, according to a new pre-clinical study by researchers at Temple University.

18 Mar 2014

Patients with both HIV and hepatitis C have 80% higher rates of serious liver disease

A new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania has found that the risk of hepatitis C-associated serious liver disease persists in HIV patients otherwise benefitting from antiretroviral therapy (ART) to treat HIV.

18 Mar 2014

Chronic News and Research

Simvastatin may slow progression of multiple sclerosis

VaxInnate starts Phase 1 clinical trial to evaluate VAX2012Q for prevention of seasonal influenza

Novel feedback provides mechanistic link between chronic inflammation and carcinogenesis

Preterm babies' guts harbor infectious microbes that can cause late-onset sepsis

New drug for patients with leukaemia and lymphoma puts an end to chemotherapy

CLL patients more prone to infections due to reduced number of antibodies

Biologists discover WBC moves to inflamed sites by walking in a stepwise manner

COPD in older adults linked with increased risk for mild cognitive impairment

Medivir announces phase III ATTAIN study of simeprevir inhibitor in treatment of adult patients with HCV

Study: Three-fold spike in heart attacks continued six years after Hurricane Katrina

Higher genetic risk of obesity may amplify effects of fried food consumption on body weight

Computer analysis of various subtypes of asthma could eventually lead to improved therapy, says study

Kessler Foundation receives grant to supports variety of rehabilitation research projects in spinal cord injury

Body clock's could be utilized to improve current therapies to delay onset of chronic lung diseases

Non-alcoholic steatohepatitis (NASH): an interview with Jean-François Mouney, CEO of Genfit

New standard for U.S. heart transplantation

Improving coordination of care for elderly patients trims costs and complications

ATS develops clinical practice guidelines to help clinicians identify, manage patients with sickle cell disease

People who experience chronic sleep disturbance could face earlier onset of dementia, Alzheimer's

Patients with both HIV and hepatitis C have 80% higher rates of serious liver disease

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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