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UNC scientists confirm and clarify key molecular details of nucleotide excision repair

Day in and day out, in our bodies, the DNA in cells is damaged for a variety of reasons, and thus intercellular DNA-repair systems are fundamental to the maintenance of life.

8 Feb 2017

Scientists secure NIH grant to test portable blood-adhesion monitor for sickle cell disease patients

Researchers at Case Western Reserve University will use a $2 million grant from the National Institutes of Health to develop and test a small, portable blood-adhesion monitor for sickle cell disease patients.

8 Feb 2017

New study uncovers important links between glioblastoma and epileptic seizures

Detecting brain tumors at the earliest possible stage and eliminating them before seizures begin might be possible one day, according to research by scientists at Baylor College of Medicine and Texas Children's Hospital.

7 Feb 2017

Studies open new windows into understanding untreatable group of common genetic disorders

Two Princeton University studies are opening important new windows into understanding an untreatable group of common genetic disorders known as RASopathies that are characterized by distinct facial features, developmental delays, cognitive impairment and heart problems.

7 Feb 2017

Melanoma research breakthrough opens up new pathways to treatment

A QUT-driven project has identified the way in which melanoma cells spread, opening up new pathways to treatment via drugs to 'turn off' the invasive gene.

7 Feb 2017

Study reveals potentially key molecular process that occurs in infective endocarditis

The human mouth can harbour more than 700 different species of bacteria. Under normal circumstances these microbes co-exist with us as part of our resident oral microbiota.

7 Feb 2017

New antibody drug shows promising results to prevent or treat HIV

A new biologic agent--the most potent of its kind so far--is showing early promise as part of a potential new strategy for treating HIV. The drug, known as 10-1074, may also offer a new way to prevent viral infection in people who are at high risk to acquire HIV, the virus that causes AIDS.

7 Feb 2017

Scientists show how immune receptor activated by bacteria contributes to diabetic bladder dysfunction

Bladder dysfunction is a reality for about half of patients with diabetes and now scientists have evidence that an immune system receptor that's more typically activated by bacteria is a major contributor.

7 Feb 2017

Study could provide novel therapeutic approach for preventing severe jaundice in newborn babies

For many newborn babies, an enzyme that breaks down the molecule bilirubin doesn't activate right away. The resulting bilirubin buildup can lead to jaundice, a typically harmless condition that causes a baby's skin to temporarily appear yellow.

6 Feb 2017

UNC scientists isolate protein that could play role in asthmatics

Researchers at the UNC School of Medicine believe they have isolated a protein that, when missing or depleted, can cause airway constriction, production of mucus, chest tightness, and difficulty breathing for the 334 million people worldwide who suffer from asthma.

6 Feb 2017

PERK protein could be target for development of new drugs for progressive supranuclear palsy

The brain disease "progressive supranuclear palsy" (PSP) is currently incurable and its symptoms can only be eased to a very limited degree. PSP impairs eye movements, locomotion, balance control, and speech.

6 Feb 2017

Scientists identify structure of androgenic receptor essential to fight against prostate cancer

A team led by researchers of the Institute of Biomedicine of the University of Barcelona and the Research Institute of the Hospital de la Santa Creu i Sant Paushows for the first time, the three-dimensional structure of the homodimeric androgen receptor ligand-binding domain, a structure that eluded researchers for years.

6 Feb 2017

Scientists discover treatment that improves symptoms in mouse model of juvenile Batten disease

Researchers at Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and King's College London have discovered a treatment that improves the neurological symptoms in a mouse model of juvenile Batten disease.

6 Feb 2017

New discovery could lead to development of new cancer treatments

Macrophages are a type of white blood cell that can engulf and destroy cancer cells. A research group led by Professor MATOZAKI Takashi, Associate Professor MURATA Yoji, and YANAGITA Tadahiko, discovered that by using an antibody for a particular protein found on macrophages, the macrophage is activated, and cancer cells are effectively eliminated.

6 Feb 2017

New NCCN patient guide for Waldenström's Macroglobulinemia helps make informed treatment decisions

A very rare sub-type of Non-Hodgkin's Lymphoma, Waldenström's Macroglobulinemia affects approximately 1,500 - 2,000 people in the United States each year. While it is not curable, Waldenström's Macroglobulinemia is slow growing, and in many patients, manageable as a chronic disease.

6 Feb 2017

New article highlights prevalence of nonmedical prescription drug use among young people

Balancing a country's need to make prescription drugs available to those in need while simultaneously curbing nonmedical use is one of our greatest challenges, according to a perspective article just published by Silvia Martins, MD, PhD, associate professor of Epidemiology at Columbia University's Mailman School of Public Health and a colleague at American University of Beirut.

6 Feb 2017

Detailed analysis of bacterial proteins offers path for new drugs to curb tuberculosis

With the first detailed analysis of a cellular component from a close relative of the pathogen that causes tuberculosis, Rockefeller scientists are suggesting strategies for new drugs to curb this growing health problem.

6 Feb 2017

WHO's new guidance aims to improve chances of survival for cancer patients

New guidance from WHO, launched ahead of World Cancer Day (4 February), aims to improve the chances of survival for people living with cancer by ensuring that health services can focus on diagnosing and treating the disease earlier.

6 Feb 2017

Cancer drug could promote regeneration of damaged heart muscle, research shows

An anticancer agent in development promotes regeneration of damaged heart muscle 0- an unexpected research finding that may help prevent congestive heart failure in the future.

3 Feb 2017

Study finds under and misuse of adjuvant endocrine therapy for breast cancer patients

A nationwide cancer registry of almost one million patients treated for hormone-sensitive breast cancer shows that one out of six women who should have received post-surgical treatment known as adjuvant endocrine therapy (AET) did not get this recommended component of care.

3 Feb 2017

Drugs News and Research

UNC scientists confirm and clarify key molecular details of nucleotide excision repair

Scientists secure NIH grant to test portable blood-adhesion monitor for sickle cell disease patients

New study uncovers important links between glioblastoma and epileptic seizures

Studies open new windows into understanding untreatable group of common genetic disorders

Melanoma research breakthrough opens up new pathways to treatment

Study reveals potentially key molecular process that occurs in infective endocarditis

New antibody drug shows promising results to prevent or treat HIV

Scientists show how immune receptor activated by bacteria contributes to diabetic bladder dysfunction

Study could provide novel therapeutic approach for preventing severe jaundice in newborn babies

UNC scientists isolate protein that could play role in asthmatics

PERK protein could be target for development of new drugs for progressive supranuclear palsy

Scientists identify structure of androgenic receptor essential to fight against prostate cancer

Scientists discover treatment that improves symptoms in mouse model of juvenile Batten disease

New discovery could lead to development of new cancer treatments

New NCCN patient guide for Waldenström's Macroglobulinemia helps make informed treatment decisions

New article highlights prevalence of nonmedical prescription drug use among young people

Detailed analysis of bacterial proteins offers path for new drugs to curb tuberculosis

WHO's new guidance aims to improve chances of survival for cancer patients

Cancer drug could promote regeneration of damaged heart muscle, research shows

Study finds under and misuse of adjuvant endocrine therapy for breast cancer patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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