Protein C News and Research

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Alzheimer’s study on mice reveals important mechanism behind neural hyperactivity

Alzheimer´s disease is the key cause of dementia in elderly patients. Those affected develop deficiencies in their abilities to learn, think logically, communicate, and to master the challenges of everyday life.

9 Feb 2018

Undergraduate researcher discovers genes linked to glioblastoma

When Leland Dunwoodie, an undergraduate researcher in biochemistry, approached his PI about wanting to start research on "some human stuff" in the spring of 2016, he didn't imagine it would lead to the discovery of 22 genes that are implicated in glioblastoma, the most aggressive type of brain cancer.

9 Feb 2018

Using CRISPR To Produce Induced Pluripotent Stem Cells

An interview with Dr. Sheng Ding about using a modified version of the CRISPR-Cas9 system to produce induced pluripotent stem cells.

9 Feb 2018

New TSRI study may provide chance to target tumors before metastasis

New research from The Scripps Research Institute may give scientists a chance to target tumors before they metastasize.

9 Feb 2018

Scientists develop ultrasound-propelled nanomotors for active delivery of Cas9-sgRNA complex

In cancer research, the “Cas-9–sgRNA” complex is an effective genomic editing tool, but its delivery across the cell membrane to the target (tumor) genome has not yet been satisfactorily solved. American and Danish scientists have now developed an active nanomotor for the efficient transport, delivery, and release of this gene scissoring system.

9 Feb 2018

Researchers develop safe, potent mRNA vaccine adjuvants that can elicit effective immune response

Production of conventional vaccines, which involves the use of live-attenuated or purified protein subunits of pathogens, is a long and complex process. Nucleic acid vaccines are safer alternatives, and allow easy adjustment of antigen to target specific pathogens.

9 Feb 2018

Cholesterol and other lipids in the blood play role in many diseases

Lipids are fatty molecules that play important signaling and storage roles in the body, but having an excess of some lipids, like cholesterol, is a risk factor for many metabolic diseases.

8 Feb 2018

Compounds isolated from rattlesnake's venom show promise to fight against hepatitis C

A group of Brazilian scientists achieved promising results using isolated compounds from the venom of the South American rattlesnake in combat of hepatitis C.

8 Feb 2018

HDAC6 inhibition could be promising therapeutic approach for peripheral neuropathies

Inhibiting HDAC6 improves the structural stability of cells and protects against neuronal damage. Leuven research uncovered that targeting this mechanism could be a promising therapeutic approach for peripheral neuropathies, whether due to Charcot-Marie-Tooth disease (CMT) or as a side effect of chemotherapy.

8 Feb 2018

Human iPS cell-derived inner ear cells may improve hereditary hearing loss

A Japanese research group has successfully grafted human iPS cell-derived inner ear cells that express human-derived proteins into the inner ears of embryonic mice.

8 Feb 2018

Study finds new stem cell pathway that allows triple-negative breast cancer to thrive

Cleveland Clinic researchers have published findings in Nature Communications on a new stem cell pathway that allows a highly aggressive form of breast cancer - triple-negative breast cancer - to thrive.

8 Feb 2018

Special protein improves survival and lung function of mice with influenza, study shows

GM-CSF, a protein that modifies the immune response to the flu, may also help reduce lung inflammation and improve survival during influenza, according to Penn State researchers.

8 Feb 2018

International research collaboration finds genetic mutation linked to Crohn's disease

A genetic mutation was found to be associated with Crohn's disease. The discovery was made by international research collaboration and was published in the prestigious journal Science Translational Medicine.

8 Feb 2018

Researchers describe human blood-nerve barrier transcriptome for the first time

Human peripheral nerves -- all the nerves outside of the central nervous system -- are protected by the blood-nerve barrier. This is a tight covering of endothelial cells that maintains the microenvironment within the nerves by restricting the amounts or types of water, ions, solutes and nutrients that can reach the axons, or electric cables within the nerves, from the blood circulation system.

8 Feb 2018

Research project succeeds in palliating kidney disease caused by diabetes in mice

Diabetes has become a major health problem worldwide; some estimates suggest that in twenty years' time there will be around 600 million diabetics. The disease is caused by impaired insulin secretion, which in turn hinders cell glucose uptake; as a result, sugar levels in the bloodstream remain excessively high.

8 Feb 2018

Dietary protein supplements provide muscle mass and strength gains for weight lifters

The debate is over. Dietary protein supplements significantly improve muscle strength and size when taken by healthy adults who lift weights, a determination reached by McMaster scientists who analyzed dozens of research studies.

8 Feb 2018

Research could pave way for treatments to reduce risk of heart disease and stroke

The discovery of a previously unknown interaction between proteins could provide a breakthrough in the prevention of damage to healthy blood vessels.

7 Feb 2018

IU scientists take important step to fight against hepatitis B with 'virus-cracking' molecules

Indiana University researchers have made an important step forward in the design of drugs that fight the hepatitis B virus, which can cause liver failure and liver cancer.

7 Feb 2018

New discovery could be key to stopping damage caused by inflammation in many diseases

A discovery by Queensland scientists could be the key to stopping damage caused by uncontrolled inflammation in a range of common diseases including liver disease, Alzheimer's and gout.

7 Feb 2018

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia

Scientists have for the first time discovered a mechanism that limits the number of "cellular janitors" in the nervous system, leading to increased risk for two neurodegenerative diseases: amyotrophic lateral sclerosis and frontotemporal dementia, according to a Keck School of Medicine of USC study published today in Nature Medicine.

7 Feb 2018

Protein C News and Research

Alzheimer’s study on mice reveals important mechanism behind neural hyperactivity

Undergraduate researcher discovers genes linked to glioblastoma

Using CRISPR To Produce Induced Pluripotent Stem Cells

New TSRI study may provide chance to target tumors before metastasis

Scientists develop ultrasound-propelled nanomotors for active delivery of Cas9-sgRNA complex

Researchers develop safe, potent mRNA vaccine adjuvants that can elicit effective immune response

Cholesterol and other lipids in the blood play role in many diseases

Compounds isolated from rattlesnake's venom show promise to fight against hepatitis C

HDAC6 inhibition could be promising therapeutic approach for peripheral neuropathies

Human iPS cell-derived inner ear cells may improve hereditary hearing loss

Study finds new stem cell pathway that allows triple-negative breast cancer to thrive

Special protein improves survival and lung function of mice with influenza, study shows

International research collaboration finds genetic mutation linked to Crohn's disease

Researchers describe human blood-nerve barrier transcriptome for the first time

Research project succeeds in palliating kidney disease caused by diabetes in mice

Dietary protein supplements provide muscle mass and strength gains for weight lifters

Research could pave way for treatments to reduce risk of heart disease and stroke

IU scientists take important step to fight against hepatitis B with 'virus-cracking' molecules

New discovery could be key to stopping damage caused by inflammation in many diseases

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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