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FDA grants permission to market new Seeker System for screening rare metabolic disorders in newborns

The U.S. Food and Drug Administration today permitted marketing of the Seeker System for the screening of four, rare Lysosomal Storage Disorders (LSDs) in newborns.

3 Feb 2017

Common drug for autoimmune disease may increase risk of myeloid neoplasms

Mayo Clinic researchers have found that azathioprine, a drug commonly used to treat autoimmune disease, may increase the risk of myeloid neoplasms.

3 Feb 2017

New Caltech study shows how chaperones protect ribosomal proteins

For proteins, this would be the equivalent of the red-carpet treatment: each protein belonging to the complex machinery of ribosomes -- components of the cell that produce proteins -- has its own chaperone to guide it to the right place at the right time and protect it from harm.

3 Feb 2017

Yale researchers identify new genetic defect in brain tumor cells that prevents DNA repair

In a new study, Yale Cancer Center researchers identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA.

3 Feb 2017

Sleep helps recalibrate brain cells responsible for learning and memory, mice study shows

Studying mice, scientists at Johns Hopkins have fortified evidence that a key purpose of sleep is to recalibrate the brain cells responsible for learning and memory so the animals can "solidify" lessons learned and use them when they awaken -- in the case of nocturnal mice, the next evening.

3 Feb 2017

TSRI chemists create new technique for constructing chiral drug molecules

Chemists at The Scripps Research Institute (TSRI) have invented a new technique for constructing chiral drug molecules.

3 Feb 2017

Vasculature in mini-brains expands research potential

Scientists have recently made a wondrous variety of mini-brains -- 3-D cultures of neural cells that model basic properties of living brains -- but a new finding could add to the field's growing excitement in an entirely new "vein": Brown University's mini-brains now grow blood vessels, too.

3 Feb 2017

Addicted individuals show weaker brain response to anticipating rewards, research finds

It may be difficult for addicted individuals to learn when they can expect a reward. This learning problem could perhaps explain why they are more prone to addiction and find it difficult to kick the habit.

3 Feb 2017

Virginia Tech researchers receive NIH grant to improve malaria drug

As long as parasites continue to mount resistance to malaria drugs, scientists will be faced with the task of developing new, improved pharmaceuticals.

3 Feb 2017

Research unravels molecular mechanisms of antisense oligonucleotides

Stanley T. Crooke, MD, PhD, CEO of Ionis Pharmaceuticals and recipient of the 2016 Lifetime Achievement Award from the Oligonucleotide Therapeutic Society presents a detailed look at the mechanisms that underlie antisense drug activity in the article entitled "Molecular Mechanisms of Antisense Oligonucleotides," published in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

2 Feb 2017

Researchers receive $2 million grant from PCORI to study effective treatment for children with KD

Kawasaki disease (KD) is an uncommon illness that affects blood vessels in the hearts of children

2 Feb 2017

Common drugs for treating back pain provide little benefit, research reveals

Commonly used non-steroidal anti-inflammatory drugs, such as ibuprofen, used to treat back pain provide little benefit, but cause side effects, according to new research from The George Institute for Global Health.

2 Feb 2017

Increased growth factor protects retinal blood vessels in animal models with diabetes

Researchers from the Schepens Eye Research Institute of Massachusetts Eye and Ear have shown that a slight increase in transforming growth factor beta (TGF-β), which is present in preclinical animal models with diabetic eye disease, protects retinal blood vessels from damage that commonly occurs in the early stages of the disease.

2 Feb 2017

Study confirms that cocaine makes users more willing to partake in risky sex

Cocaine use has long been tied anecdotally to higher-than-usual rates of impulsive behavior, including risky sex, but the tie-in has been difficult to study with any scientifically controlled rigor.

2 Feb 2017

New study offers insights into how antidepressants work in the brain

When they work, antidepressant medications may take weeks or months to alleviate symptoms of depression.

2 Feb 2017

Researchers identify new mechanism that protects from bacterial infections

An international team led by the University if Barcelona has identified a new antibacterial mechanism that protects macrophages - defense cells in the immune system- from the infection of the bacteria Salmonella enterica serovar Typhimurium, a pathogen associated with several gastrointestinal diseases.

2 Feb 2017

Nicotine creates cascade of effects in the brain that get worse over time

The first period of nicotine abstinence proceeded as expected. The surprise came after three months when the lab rats suddenly became fearless and sought out well-lighted areas that prey animals normally avoid. At the same time, signaling in the brain's reward system changed, as shown by a study at Sahlgrenska Academy.

2 Feb 2017

Autologous hematopoietic cell transplant may induce sustained remission of multiple sclerosis

New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS), an autoimmune disease in which the immune system attacks the central nervous system.

2 Feb 2017

UNC-Chapel Hill researchers show how human stem cells can hunt and kill brain cancer

In a rapid-fire series of breakthroughs in just under a year, researchers at the University of North Carolina at Chapel Hill have made another stunning advance in the development of an effective treatment for glioblastoma, a common and aggressive brain cancer.

2 Feb 2017

Neutron analysis helps better understand key bacterial enzyme implicated in stomach cancer

Neutron analysis at the Department of Energy's Oak Ridge National Laboratory is helping researchers better understand a key enzyme found in a bacterium known to cause stomach cancer.

2 Feb 2017

Drugs News and Research

FDA grants permission to market new Seeker System for screening rare metabolic disorders in newborns

Common drug for autoimmune disease may increase risk of myeloid neoplasms

New Caltech study shows how chaperones protect ribosomal proteins

Yale researchers identify new genetic defect in brain tumor cells that prevents DNA repair

Sleep helps recalibrate brain cells responsible for learning and memory, mice study shows

TSRI chemists create new technique for constructing chiral drug molecules

Vasculature in mini-brains expands research potential

Addicted individuals show weaker brain response to anticipating rewards, research finds

Virginia Tech researchers receive NIH grant to improve malaria drug

Research unravels molecular mechanisms of antisense oligonucleotides

Researchers receive $2 million grant from PCORI to study effective treatment for children with KD

Common drugs for treating back pain provide little benefit, research reveals

Increased growth factor protects retinal blood vessels in animal models with diabetes

Study confirms that cocaine makes users more willing to partake in risky sex

New study offers insights into how antidepressants work in the brain

Researchers identify new mechanism that protects from bacterial infections

Nicotine creates cascade of effects in the brain that get worse over time

Autologous hematopoietic cell transplant may induce sustained remission of multiple sclerosis

UNC-Chapel Hill researchers show how human stem cells can hunt and kill brain cancer

Neutron analysis helps better understand key bacterial enzyme implicated in stomach cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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