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New test for detecting small amounts of proteins in the blood

Researchers at the University of Pennsylvania School of Medicine have developed a paradigm-shifting method for detecting small amounts of proteins in the blood.

13 Mar 2006

Transplanting a pair of kidneys with limited function into one patient may offer one solution to short supply of donated kidneys

Transplanting a pair of kidneys with limited function into one patient can be just as successful as the standard procedure in which a patient receives a single kidney, according to new research at Wake Forest University Baptist Medical Center.

13 Mar 2006

Wobble pairs make RNA more reactive

The wealth of information contained in a strand of genetic material boils down to sequences of matched pairs of nucleotides that cellular machinery decodes to construct proteins.

13 Mar 2006

Nematode hormone discovery may aid fight against parasitic disease

New research at UT Southwestern Medical Center shows that on a biochemical level, hormone-like molecules in tiny worms called nematodes work similarly to the way in which certain hormones work in humans - findings that one day may help eradicate worm infections that afflict a third of the world's population.

9 Mar 2006

Saliva RNA test for oral cancer

Oral cancer is the 6th most common cancer in men and the 14th most common cancer in women. In the US, oral cancer will be diagnosed in an estimated 30,000 Americans this year and will cause more than 8,000 deaths.

9 Mar 2006

Thalidomide, Lenalidomide show promise against Lou Gehrig's disease

New animal research suggests that two well-studied drugs, thalidomide and its derivative, lenalidomide, might extend the survival of patients with the neurological disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

9 Mar 2006

Penn researchers study link between potassium and sodium channels aiming at new treatments for neurological diseases

Researchers at the University of Pennsylvania School of Medicine have discovered the mechanism that facilitates how two ion channels collaborate in the control of electrical signals in the brain.

9 Mar 2006

Researchers find compound that interferes with the pathogenic effects of Huntington's disease

There is no cure for Huntington's, a neurodegenerative disorder that now afflicts 30,000 Americans, with another 150,000 at risk. The fatal disease, which is genetically inherited, usually strikes in midlife and causes uncontrolled movements, loss of cognitive function and emotional disturbance.

9 Mar 2006

Thalidomide improves remission in myeloma

Myeloma is one of the least curable cancers and involves plasma cells, the white blood cells that produce antibodies.

9 Mar 2006

Scientists create a mosquito resistant to Type 2 dengue fever virus

Researchers have successfully created a genetically engineered mosquito that shows a high level of resistance against the most prevalent type of dengue fever virus, providing a powerful weapon against a disease that infects 50 million people each year.

9 Mar 2006

G protein-coupled receptors cool passion of 'kiss and run' nerve cells

A new subtlety in the process of how the body's nervous system relays information may hinge on how "wet" the "kiss" is when one neuron fires a packet of neurotransmitter across a synapse to a receptive nerve cell.

9 Mar 2006

Details of protein-cleaving complex key to microbe's survival may improve drug design

With the hope of designing more effective treatments for tuberculosis (TB), scientists from the U.S. Department of Energy's Brookhaven National Laboratory and collaborating institutions have published the first detailed reports on the biochemistry and structure of a protein-cleaving complex that is essential to the TB bacterium's survival.

9 Mar 2006

New way to study proteins in live cells

For the first time, Johns Hopkins researchers were able to easily jumpstart the activity of a well-known cancer protein in live cells with a small molecule, a strategy that pinpointed key players in the cancer process and can be used to determine new therapeutic targets.

9 Mar 2006

Genetic switch that turns off an oxygen-poor cell's combustion engine - finding has potential to limit toxic molecules

Johns Hopkins researchers have discovered a previously unrecognized role played by the gene HIF-1 as it helps cell survive when a lack of oxygen decreases production of an energy-rich molecule called ATP and increases production of toxic molecules.

9 Mar 2006

New genome-wide map of miRNA-MRNA interactions

Researchers at New York University's Center for Comparative Functional Genomics and the University of California, Berkeley have used computational analyses to predict a genome-wide map of microRNA (miRNA) targets in the animal model organism, Caenorhabditis elegans (C. elegans).

9 Mar 2006

Cornell develops technique for making living, functional cells glow

The development gives researchers insights into how hearts develop in living mouse embryos and could improve our understanding of irregular heartbeats, known as arrhythmias, as well as open doors to observing cellular processes to better understand basic physiology and disease.

9 Mar 2006

G Protein News and Research

New test for detecting small amounts of proteins in the blood

Transplanting a pair of kidneys with limited function into one patient may offer one solution to short supply of donated kidneys

Wobble pairs make RNA more reactive

Nematode hormone discovery may aid fight against parasitic disease

Saliva RNA test for oral cancer

Thalidomide, Lenalidomide show promise against Lou Gehrig's disease

Penn researchers study link between potassium and sodium channels aiming at new treatments for neurological diseases

Researchers find compound that interferes with the pathogenic effects of Huntington's disease

Thalidomide improves remission in myeloma

Scientists create a mosquito resistant to Type 2 dengue fever virus

G protein-coupled receptors cool passion of 'kiss and run' nerve cells

Details of protein-cleaving complex key to microbe's survival may improve drug design

New way to study proteins in live cells

Genetic switch that turns off an oxygen-poor cell's combustion engine - finding has potential to limit toxic molecules

New genome-wide map of miRNA-MRNA interactions

Cornell develops technique for making living, functional cells glow

ATF2 protein may play a crucial role in cancer's ability to resist chemotherapy and radiation treatment

Novel compound may help fight obesity

Soy protein, almonds, plant sterol enriched margarines, oats and barley among most effective cholesterol-lowering foods

Major biomarker candidates for Alzheimer's disease explored

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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