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UCSF study marks important step toward finding cure for Ebola

In experiments carried out partly at the Department of Energy's SLAC National Accelerator Laboratory, scientists have determined in atomic detail how a potential drug molecule fits into and blocks a channel in cell membranes that Ebola and related "filoviruses" need to infect victims' cells.

15 Mar 2016

Heart failure drug has unexpected ability to block herpesvirus infection

Today, there is only one class of antiviral medicines against herpesviruses - a family of viruses that cause mononucleosis, herpes, and shingles, among other illnesses - meaning options for treating these infections are limited. If viruses become resistant to these frontline treatments, a growing problem particularly in clinical settings, there are no alternative drugs to serve as backup.

15 Mar 2016

New drug could transform treatment of metastatic triple negative breast cancer

A team of investigators from Houston Methodist Research Institute may have transformed the treatment of metastatic triple negative breast cancer by creating the first drug to successfully eliminate lung metastases in mice.

15 Mar 2016

Liposomes can be potential candidates for drug delivery to constricted coronary arteries

Liposomes are currently used as drug delivery vehicles but recognized by the immune system. Scientists from the universities of Basel and Fribourg have shown that special artificial liposomes do not elicit any reaction in human and porcine sera as well as pigs.

14 Mar 2016

Population health research on cardiovascular health finds positive results

In 2009, Minneapolis Heart Institute Foundation, along with Allina Health, New Ulm Medical Center and the community of New Ulm, Minnesota, began a 10-year population health research project to learn if heart attacks and heart disease risk factors within a community could be decreased through community efforts. Results for the first five years have been released, and the initial findings are positive.

14 Mar 2016

Researchers exploring ways to prevent radiation-induced cancer risk in astronauts

NASA limits an astronaut's radiation exposures to doses that keep their added risk of fatal cancer below 3 percent. Unfortunately, that ceiling restricts the time an astronaut may spend in space, which in turn restricts the ability to perform longer missions, say a mission to Mars.

14 Mar 2016

Paroxysmal AF patients who practice yoga have better quality of life

Yoga improves quality of life in patients with paroxysmal atrial fibrillation, according to research published today in the European Journal of Cardiovascular Nursing. Heart rate and blood pressure also decreased in patients who did yoga.

14 Mar 2016

Blueberries can have a real benefit in lowering risk of heart disease, cancer and Alzheimer's

The blueberry, already labeled a "super fruit" for its power to potentially lower the risk of heart disease and cancer, also could be another weapon in the war against Alzheimer's disease. New research being presented today further bolsters this idea, which is being tested by many teams.

14 Mar 2016

Synthetic nanoparticle can light up and treat atherosclerotic plaques

Atherosclerosis, a disease in which plaque builds up inside arteries, is a prolific and invisible killer, but it may soon lose its ability to hide in the body and wreak havoc. Scientists have now developed a nanoparticle that functionally mimics nature's own high-density lipoprotein (HDL). The nanoparticle can simultaneously light up and treat atherosclerotic plaques that clog arteries. Therapy with this approach could someday help prevent deadly heart attacks and strokes.

14 Mar 2016

Tai chi exercise improves outcomes in older fallers

Recently, researchers compared the effects of tai chi to leg strengthening exercises (a physical therapy called "lower extremity training," or LET) in reducing falls. Falls are a leading cause of serious injuries in older adults and can lead to hospitalization, nursing home admission, and even death.

13 Mar 2016

Beta-blockers could have potential benefit for COPD patients

Beta-blockers could be used to reduce the risk of chronic obstructive pulmonary disease (COPD) exacerbations, according to new findings.

13 Mar 2016

Valley Hospital to evaluate potential new treatment alternative for AFib patients

The Valley Hospital in Ridgewood, NJ, is one of 15 U.S. sites currently enrolling patients in a research study to evaluate a potential new treatment alternative for patients with symptomatic persistent and long standing persistent atrial fibrillation (AFib).

13 Mar 2016

People with type 2 diabetes, OSA may not experience improved glycemic control with CPAP

People with type 2 diabetes and obstructive sleep apnea (OSA) may not experience improved glycemic control by using continuous positive airway pressure, or CPAP, as some studies have suggested, according to the results of a randomized, controlled trial published online ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

13 Mar 2016

Lots of 'good' cholesterol may be bad

Recent research has identified a genetic mutation that prevents high-density-lipoprotein (HDL) cholesterol from being taken up by cells.

11 Mar 2016

Study shows gut microbes alter platelet function, heightens risk of heart attack and stroke

In a combination of both clinical studies of over 4,000 patients and animal model studies, Cleveland Clinic researchers have demonstrated -- for the first time -- that gut microbes alter platelet function and risk of blood clot-related illnesses like heart attack and stroke.

11 Mar 2016

Enhanced diet helps slow progression of hereditary deafness

An enhanced diet helped reduce hearing loss in mice with the genetic mutation most commonly responsible for childhood deafness, new research suggests.

11 Mar 2016

Scientists map biological networks of genes to gain new insights on disease mechanisms

Innovative software tools allowed the scientists to construct accurate "maps" of gene networks for about 400 different human cell and tissue types, ranging from immune cells to brain tissues, whereas previous studies were limited to just one or few tissues.

11 Mar 2016

New RI-MUHC-led study may change the way we think about prescribing statins

Millions of people today take statins to help lower their cholesterol level. Currently statins are prescribed to patients based on their future risk of cardiovascular disease - mainly driven by age - which excludes many individuals who may benefit from them. A new study led by the Research Institute of the McGill University Health Centre in Montreal, with collaborators from the United-States, is changing the way we think about prescribing statins. The research team has developed a new approach to determine which individuals should receive these important medications.

11 Mar 2016

Findings offer novel way for creating drugs to stop mitochondria from destroying cells during stress

Malfunctioning mitochondria — the power plants in cells — are behind the damage caused by strokes, heart attacks, and neurodegenerative diseases, but little has been known about how to stop these reactors from melting down, destroying cells and tissue. Mitochondria also take up calcium, which regulates energy production.

11 Mar 2016

Springing forward one hour may lead to increased heart attack risk

Many people may groan about losing an hour of sleep March 13, but there may be a more serious reason to be mindful of daylight saving time.

11 Mar 2016

Heart News and Research

UCSF study marks important step toward finding cure for Ebola

Heart failure drug has unexpected ability to block herpesvirus infection

New drug could transform treatment of metastatic triple negative breast cancer

Liposomes can be potential candidates for drug delivery to constricted coronary arteries

Population health research on cardiovascular health finds positive results

Researchers exploring ways to prevent radiation-induced cancer risk in astronauts

Paroxysmal AF patients who practice yoga have better quality of life

Blueberries can have a real benefit in lowering risk of heart disease, cancer and Alzheimer's

Synthetic nanoparticle can light up and treat atherosclerotic plaques

Tai chi exercise improves outcomes in older fallers

Beta-blockers could have potential benefit for COPD patients

Valley Hospital to evaluate potential new treatment alternative for AFib patients

People with type 2 diabetes, OSA may not experience improved glycemic control with CPAP

Lots of 'good' cholesterol may be bad

Study shows gut microbes alter platelet function, heightens risk of heart attack and stroke

Enhanced diet helps slow progression of hereditary deafness

Scientists map biological networks of genes to gain new insights on disease mechanisms

New RI-MUHC-led study may change the way we think about prescribing statins

Findings offer novel way for creating drugs to stop mitochondria from destroying cells during stress

Springing forward one hour may lead to increased heart attack risk

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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