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New method helps study chaotic genomes of cancer cells more precisely than ever before

Scientists of the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg have developed a method for analysing the genome of cancer cells more precisely than ever before.

31 Oct 2015

Key protein controls stem cell properties that could make them useful in regenerative medicine

A key protein controls stem cell properties that could make them more useful in regenerative medicine, according to a study led by Mount Sinai researchers and published online today in the journal Cell Stem Cell.

31 Oct 2015

Resistance to CD19 CAR T-cell therapy can be caused by CD19 splicing alterations

Resistance to CD19 CAR T-cell therapy, a type of immunotherapy that yields long-lasting remissions in many patients with B-cell leukemia, can be caused by CD19 splicing alterations, leading to loss of certain parts of the CD19 protein that are recognized by the CAR T cells.

31 Oct 2015

GUMC study examines patients' most preferred methods for receiving common medical test results

The results of common medical tests are sometimes delivered to patients by email, letters or voice mail, but are these the most preferred methods? According to one of the first studies to look at this question, the answer is no.

31 Oct 2015

Blocking calcium-signaling pathway could inhibit Ebola virus and other sources of deadly infections

The Ebola virus acts fast. The course of infection, from exposure to recovery, or death, can take as little as two weeks. That may not leave enough time for the immune system to mount an effective response.

31 Oct 2015

Routine clinical features may aid BVFTD diagnostic accuracy

Researchers have identified clinical features that can help determine which patients assessed for behavioural variant frontotemporal dementia are most likely to actually have the condition.

30 Oct 2015

Q BioMed signs definitive license agreement with Mannin Research

Q BioMed Inc., a biotechnology acceleration company is pleased to announce it has signed a definitive license, with the option to acquire, the platform technology assets of Mannin Research Inc.

30 Oct 2015

New online tool may allow researchers explore formation of hair follicles

A new online database will empower researchers exploring how hair follicles and the surrounding skin develop, according to an article published recently in the journal Developmental Cell. The work is central to understanding the interactions between stem cells and their environment - or "niche cells" - during fetal development, and will specifically facilitate future attempts to make skin grafts with functional hair follicles or to regenerate lost hair in patients.

30 Oct 2015

Study reports discovery of new class of DNA repair enzyme

This year's Nobel Prize in chemistry was given to three scientists who each focused on one piece of the DNA repair puzzle. Now a new study, reported online Oct. 28 in the journal Nature, reports the discovery of a new class of DNA repair enzyme.

30 Oct 2015

Women with elevated breast cancer risk can benefit from regular physical activity

Regular physical activity could play a role in helping women at high-risk of breast cancer delay the need for drastic preventive measures such as prophylactic mastectomy, according to new research led by the Perelman School of Medicine at the University of Pennsylvania.

30 Oct 2015

Study suggests a neural pathway through which early life stress may contribute to depression

Early life stress is a major risk factor for later episodes of depression. In fact, adults who are abused or neglected as children are almost twice as likely to experience depression.

30 Oct 2015

Single gene variation may influence obesity in children, adults

A single variation in the gene for brain-derived neurotropic factor (BDNF) may influence obesity in children and adults, according to a new study funded by the National Institutes of Health.

30 Oct 2015

Gut bacteria may increase risk of metabolic syndrome

An excess of bacteria in the gut can change the way the liver processes fat and could lead to the development of metabolic syndrome, according to health researchers.

30 Oct 2015

New clinical trial on breast cancer may help treat and control disease

A new clinical trial at Sanford Health is exploring how genetic changes that occur during breast cancer might help health care providers better identify, treat and control the disease.

30 Oct 2015

Study reveals mechanism behind protein-related diseases

Dartmouth researchers have found that some proteins turn into liquid droplets on the way to becoming toxic solids implicated in neurodegenerative diseases and other genetic disorders.

30 Oct 2015

Halozyme Therapeutics announces initiation of rivipansel Phase 1 clinical trial

Halozyme Therapeutics, Inc. today announced that the first healthy subject has been dosed in a Phase 1 clinical trial evaluating the safety, tolerability and pharmacokinetics of a subcutaneous formulation of rivipansel, a compound discovered by GlycoMimetics, Inc. and being developed by Pfizer Inc., using Halozyme's ENHANZE formulation.

30 Oct 2015

New computer-based modeling may help improve outcomes for babies with neonatal abstinence syndrome

Computer-based modeling is helping to further reduce length of hospital stay and duration of treatment with opioids that are used therapeutically to wean babies born in withdrawal from drugs their mothers have taken. This condition is known as neonatal abstinence syndrome (NAS).

30 Oct 2015

Ultragenyx, Arcturus sign agreement to develop mRNA therapeutics to certain rare diseases

Ultragenyx Pharmaceutical Inc., a biopharmaceutical company focused on the development of novel products for rare and ultra-rare diseases, and Arcturus Therapeutics, Inc., a leading RNA medicines company, today announced that they have entered into a research collaboration and license agreement to discover and develop messenger RNA (mRNA) therapeutics to certain rare disease targets using Arcturus' UNA Oligomer chemistry and LUNAR nanoparticle delivery platform.

29 Oct 2015

Scientists call for coordinated effort to drive cutting edge microbiome research

A consortium of 48 scientists from 50 institutions in the United States - including Pamela Silver, Ph.D., a Core Faculty member at the Wyss Institute for Biologically Inspired Engineering at Harvard University - are calling for a Unified Microbiome Initiative that would span national cross-institutional and cross-governmental agency support.

29 Oct 2015

First consensus guidelines on sharing genomic research findings on adults, children with family members

A blue-ribbon project group funded by the National Institutes of Health has published the first consensus guidelines on how researchers should share genomic findings in research on adults and children with other family members. The recommendations, published in the Journal of Law, Medicine & Ethics, offer direction on sharing information before and after the death of an individual research participant.

29 Oct 2015

Genetic News and Research

New method helps study chaotic genomes of cancer cells more precisely than ever before

Key protein controls stem cell properties that could make them useful in regenerative medicine

Resistance to CD19 CAR T-cell therapy can be caused by CD19 splicing alterations

GUMC study examines patients' most preferred methods for receiving common medical test results

Blocking calcium-signaling pathway could inhibit Ebola virus and other sources of deadly infections

Routine clinical features may aid BVFTD diagnostic accuracy

Q BioMed signs definitive license agreement with Mannin Research

New online tool may allow researchers explore formation of hair follicles

Study reports discovery of new class of DNA repair enzyme

Women with elevated breast cancer risk can benefit from regular physical activity

Study suggests a neural pathway through which early life stress may contribute to depression

Single gene variation may influence obesity in children, adults

Gut bacteria may increase risk of metabolic syndrome

New clinical trial on breast cancer may help treat and control disease

Study reveals mechanism behind protein-related diseases

Halozyme Therapeutics announces initiation of rivipansel Phase 1 clinical trial

New computer-based modeling may help improve outcomes for babies with neonatal abstinence syndrome

Ultragenyx, Arcturus sign agreement to develop mRNA therapeutics to certain rare diseases

Scientists call for coordinated effort to drive cutting edge microbiome research

First consensus guidelines on sharing genomic research findings on adults, children with family members

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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