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Multivalent effects of RGD peptides obtained by nanoparticle display

While a growing body of literature has shown that nanoparticle targeting can improve drug delivery and tumor imaging, there have been few systematic studies examining the net positive effect of nanoparticle targeting.

23 Oct 2006

Functionalization of individual ultra-short single-walled carbon nanotubes

While most research aimed at developing carbon nanotubes as tumor-targeting drug and imaging agent delivery vehicles has focused on full-length nanotubes, Lon Wilson, Ph.D., and his colleagues at Rice University have been working with ultra-short nanotubes that cells appear to take up more efficiently than their longer counterparts.

23 Oct 2006

Gene called Kibra plays an important role in memory

Researchers at the Translational Genomics Research Institute (TGen) have announced the discovery of a gene that plays a significant role in memory performance in humans.

20 Oct 2006

Flexible interface between DNA ligase and a heterotrimeric sliding clamp supports conformational switching and efficient ligation of DNA

Scientists investigating an important DNA-repair enzyme now have a better picture of the final steps of a process that glues together, or ligates, the ends of DNA strands to restore the double helix.

20 Oct 2006

Parkinson's disease affects more than just motor control

Although Parkinson's disease is most commonly viewed as a "movement disorder," scientists have found that the disease also causes widespread abnormalities in touch and vision - effects that have now been verified using functional magnetic resonance imaging (fMRI) of the brain.

17 Oct 2006

Researchers find areas in the brain that indicate bilingualism

The finding sheds new light on decades of debate about how the human brain's language centers may actually be enhanced when faced with two or more languages as opposed to only one.

17 Oct 2006

Cocaine addicts have an altered perception of reward

People addicted to cocaine have an impaired ability to perceive rewards and exercise control due to disruptions in the brain's reward and control circuits, according to a series of brain-mapping studies and neuropsychological tests conducted at the U.S. Department of Energy's Brookhaven National Laboratory.

16 Oct 2006

Laser technique shows women's skin ages faster than men's

According to German researchers women's skin ages faster than men's - so men become distinguished women just look older!

4 Oct 2006

Research implicates brain circuits involved in drug craving and emotional response to food

Researchers at the U.S. Department of Energy's Brookhaven National Laboratory have found new clues to how the brain and the stomach interact with emotions to cause overeating and obesity.

2 Oct 2006

Multispectral imaging of clinically relevant cellular targets in tonsil and lymphoid tissue using semiconductor quantum dots

When pathologists examine tissue samples in order to diagnose cancer of the lymphatic system, they examine the relative amounts of a group of proteins known as Cluster of Differentiation markers.

25 Sep 2006

Cigna provides data on cost, quality of services to web site

Cigna, which last year began to post cost and quality information for inpatient services performed at hospitals on a Web site for members, this week added data for outpatient services performed at stand-alone surgical centers, the Fort Worth Star-Telegram reports (Perotin, Fort Worth Star-Telegram, 9/20).

22 Sep 2006

Researchers identify neurocircuit that controls the brain's response to fear

Results suggest that it may be possible to understand psychiatric disorders, such as anxiety or depression, from the underlying neurophysiology - workings of the brain.

21 Sep 2006

How the brain resolves emotional conflict

Daily life requires that people cope with distracting emotions--from the basketball player who must make a crucial shot amidst a screaming crowd, to a salesman under pressure delivering an important pitch to a client.

21 Sep 2006

Earlier detection and treatment of kidney cancer not decreasing mortality

The number of cases of kidney cancer has been rising over the last two decades, and new research from the University of Michigan Comprehensive Cancer Center shows that this increase is driven largely by the detection of small, presumably curable, kidney masses.

19 Sep 2006

Cisplatin nanoliposomes for cancer therapy

Cisplatin is one of the most powerful and effective drugs for treating a wide variety of cancers, but many tumors develop resistance to this drug, ultimately limiting its benefits for cancer patients.

19 Sep 2006

Australian world first in cancer therapy screening

A new approach in the treatment of breast cancer, appears to be a world first for Australian doctors.

13 Sep 2006

Four largest Massachusetts insurers plan double-digit premium increases for 2007

The four largest health insurers in Massachusetts -- Blue Cross Blue Shield of Massachusetts, Harvard Pilgrim Health Care, Tufts Health Plan and Fallon Community Health Plan -- in 2007 are expected for most of their insurance options to raise premiums by at least 10% for the seventh consecutive year, the Boston Globe reports.

13 Sep 2006

Could quantum dots hold the cure to cancer?

Review of quantum dot technologies for cancer detection and treatment.

13 Sep 2006

MRI tracks survival of pancreatic islets after transplantation

Magnetic resonance imaging (MRI) with an approved contrast agent may provide a practical way of monitoring the survival of transplanted pancreatic islets.

12 Sep 2006

New screening method shows how nanoparticles interact with human cells

Scientists at the Brookhaven National Laboratory have developed a screening method to examine how newly made nanoparticles interact with human cells following exposure for various times and doses. Using this new method, the investigators have been able to visualize how human cells interact with some specific types of carbon nanoparticles.

12 Sep 2006