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Targeting small group of brain cells may reduce opioid addiction risk

Researchers at Duke University School of Medicine are investigating how to keep opioids' pain-relieving benefits while reducing their addictive potential. In a study published in Nature, they report a step toward that goal.

7 Aug 2026

Study uncovers molecular trigger behind pyrin inflammation in familial Mediterranean fever

Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease in which the body's own immune system overreacts to minimal or inappropriate stimuli, producing recurrent attacks of fever and painful inflammation.

7 Aug 2026

Thinning cancer cells' sugar coating could expose tumors to immune attack

Like spies evading detection through being masters of disguise, many cancer cells are adorned with a copious coat of sugar-derived molecules that throws the proverbial hounds of our immune systems off the scent.

7 Aug 2026

Researchers find a new genetic vulnerability in acute myeloid leukemia

A study published in Nature Cell Biology reports a new vulnerability in acute myeloid leukemia (AML) that might lead to novel therapies to treat this cancer while minimizing harm to normal cells.

7 Aug 2026

Researchers discover smart molecular glue that activates inside oxidative cancer cells

Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein degradation drug candidates.

7 Aug 2026

Autophagy modulation emerges as a strategy against cisplatin-resistant gastric cancer

Drug resistance remains one of the greatest obstacles to successful treatment of gastric cancer, limiting the long-term effectiveness of the widely used chemotherapy drug cisplatin.

6 Aug 2026

IL-6 receptor blockers show promise for preventing MOGAD relapses

An international study led by Mayo Clinic researchers has identified interleukin-6 (IL-6) receptor blockers as a promising option for preventing relapses in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). MOGAD is a rare autoimmune neurological disorder that can cause vision loss, paralysis and other serious neurological complications.

6 Aug 2026

Early radionuclide therapy delays progression in metastatic prostate cancer

Earlier use of a targeted radionuclide therapy delays metastatic prostate cancer progression when administered as part of a trio of drugs, according to a phase 3 clinical trial led by Weill Cornell Medicine, NewYork-Presbyterian, Memorial Sloan Kettering Cancer Center and investigators at several other institutions worldwide.

6 Aug 2026

Omega-3 and ASA combination shows promise for severe periodontitis

A combination of omega-3 and low-dose acetylsalicylic acid (ASA) produced results comparable to antibiotics in treating severe periodontitis.

6 Aug 2026

Combining genetics and AI to discover new osteoarthritis drugs

Osteoarthritis (OA) is a chronic, painful joint disease and a leading cause of disability. Despite its prevalence, therapies for osteoarthritis are limited and focus on symptom management.

6 Aug 2026

Researchers uncover mechanism linking skin inflammation to body-wide allergies

Our bodies experience allergic reactions when the immune system mistakenly overreacts to harmless substances, known as allergens, such as pollen, dust, or certain foods.

6 Aug 2026

Genetic changes in zebrafish reveal new pathways for back pain

Neck and back pain could be caused by changes in gene activity that trigger the breakdown of the spine's natural shock absorbers, new research suggests.

6 Aug 2026

Nerve-tumor interactions emerge as a transformative frontier in oncology

A new review article highlights a rapidly emerging frontier in oncology: the dynamic and influential relationship between nerves and tumors.

6 Aug 2026

Galápagos wastewater is creating new reservoirs of antibiotic-resistant bacteria

Portable field surveillance reveals how untreated sewage is reshaping coastal microbial communities and spreading diverse resistance genes across one of the world’s most protected marine environments.

6 Aug 2026

Scientists combine imaging and phototherapy in a single tool against glioblastoma

Glioblastoma is the most aggressive form of brain cancer.

6 Aug 2026

Study reveals treatment gaps for atypical Alzheimer's disease patients

Many people with less common forms of Alzheimer's disease may not qualify for newer anti-amyloid treatments designed to slow the disease, according to a study published August 5, 2026, in Neurology®, the medical journal of the American Academy of Neurology.

5 Aug 2026

AI tool aims to accelerate Alzheimer's treatment through faster referrals

Vanderbilt Health researchers have received a grant from Eli Lilly and Company, a multinational pharmaceutical company headquartered in Indianapolis, to build an artificial intelligence (AI) tool within the electronic health record system (EHR) to get patients with Alzheimer's disease to treatment faster.

5 Aug 2026

International team builds comprehensive cancer models for future drug development

To develop new targeted treatments for cancer, scientists need tissue models that accurately represent the genetic and molecular traits of the cancer they're studying.

5 Aug 2026

Experimental drug CS18 shows promise for overcoming cancer treatment resistance

Researchers at Baylor College of Medicine have developed a drug called CS18 that disrupts the ability of cancer cells to survive therapy. The findings, published in Science Advances, support exploring the possibility of using CS18 to treat human cancer in the future.

5 Aug 2026

Limited PBS coverage widens pregnancy nausea treatment disparities in Australia

Pregnant women in Australia are facing an unfair two-tiered system for managing morning sickness, with financial status impacting who can access the full range of modern anti-nausea medications available, rather than simply clinical need.

5 Aug 2026