Embryonic Stem Cell News and Research

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Controversy lurks as cloning technique yields embryos with eye on stem cell therapies

Political and ethical fights over human cloning may follow the latest stem cell therapy advance after scientists created embryos that are genetic copies of living people in an effort to treat diseases such as Alzheimer's.

17 May 2013

UCSF researchers create first functioning human thymus tissue from embryonic stem cells

Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells, in the laboratory. The researchers showed that, in mice, the tissue can be used to foster the development of white blood cells the body needs to mount healthy immune responses and to prevent harmful autoimmune reactions.

17 May 2013

First Edition: May 16, 2013

Today's headlines detail the Senate confirmation of Acting Chief Marilyn Tavenner to run the Centers for Medicare & Medicaid Services.

16 May 2013

Research breakthrough: Human skin cells becomes embryonic stem cells

Scientists at Oregon Health & Science University and the Oregon National Primate Research Center have successfully reprogrammed human skin cells to become embryonic stem cells capable of transforming into any other cell type in the body.

16 May 2013

Modifications in key epigenetic markers influence human embryonic stem cells

Scientists have long known that control mechanisms known collectively as "epigenetics" play a critical role in human development, but they did not know precisely how alterations in this extra layer of biochemical instructions in DNA contribute to development.

10 May 2013

Biomedical engineers grow 3D human heart muscle that acts just like natural tissue

Duke University biomedical engineers have grown three-dimensional human heart muscle that acts just like natural tissue. This advancement could be important in treating heart attack patients or in serving as a platform for testing new heart disease medicines.

7 May 2013

Discovery may lead to new treatment for neurodevelopmental, neurodegenerative disorders

A key type of human brain cell developed in the laboratory grows seamlessly when transplanted into the brains of mice, UC San Francisco researchers have discovered, raising hope that these cells might one day be used to treat people with Parkinson's disease, epilepsy, and possibly even Alzheimer's disease, as well as and complications of spinal cord injury such as chronic pain and spasticity.

5 May 2013

Study reveals how the properties of embryonic stem cells are controlled

Scientists have made a fundamental discovery about how the properties of embryonic stem cells are controlled.

3 May 2013

Newly discovered ‘master regulator’ gene may help develop novel treatment for drug-resistant tumors

Researchers at Johns Hopkins have identified a gene that, when repressed in tumor cells, puts a halt to cell growth and a range of processes needed for tumors to enlarge and spread to distant sites. The researchers hope that this so-called "master regulator" gene may be the key to developing a new treatment for tumors resistant to current drugs.

3 May 2013

CHOP research offers insights into epilepsy, schizophrenia, other neuropsych disorders

Medical researchers have manipulated human stem cells into producing types of brain cells known to play important roles in neurodevelopmental disorders such as epilepsy, schizophrenia and autism.

3 May 2013

ACT announces European phase I clinical trial for Stargardt's disease using retinal pigment epithelial cells

Advanced Cell Technology, Inc. a leader in the field of regenerative medicine, today announced treatment of the first patient in the third dosage cohort, and seventh patient overall, in its European Phase I clinical trial for Stargardt's macular dystrophy (SMD) using retinal pigment epithelial (RPE) cells derived from human embryonic stem cells (hESCs).

26 Apr 2013

Individual hydroxymethylcytosine molecules in DNA detected by new method involving chemical modification and nanopore analysis

Changes in the bases that make up DNA act as markers, telling a cell which genes it should read and which it shouldn’t. In the journal Angewandte Chemie, a British team has now introduced a new method that makes it possible to enrich the rare gene segments that contain the modified base hydroxymethylcytosine and to identify individual hydroxymethylcytosine molecules in DNA. Such modifications are associated with autoimmune diseases and cancer.

24 Apr 2013

Study: Stem cell transplant heals neurological deficits in mice

For the first time, human embryonic stem cells have been transformed into nerve cells that helped mice regain the ability to learn and remember.

22 Apr 2013

Researchers transform skin cells directly into oligodendrocyte precursor cells

Researchers at the Stanford University School of Medicine have succeeded in transforming skin cells directly into oligodendrocyte precursor cells, the cells that wrap nerve cells in the insulating myelin sheaths that help nerve signals propagate.

16 Apr 2013

Junk DNA plays important role in brain development

Specific DNA once dismissed as junk plays an important role in brain development and might be involved in several devastating neurological diseases, UC San Francisco scientists have found.

16 Apr 2013

New research reveals how autophagy keeps neural stem cells to replace damaged brain, nerve cells

Deep inside your brain, a legion of stem cells lies ready to turn into new brain and nerve cells whenever and wherever you need them most. While they wait, they keep themselves in a state of perpetual readiness - poised to become any type of nerve cell you might need as your cells age or get damaged.

11 Apr 2013

Scientists develop a new way to generate induced pluripotent stem cell lines from human fibroblasts

A team of New York Stem Cell Foundation (NYSCF) Research Institute scientists led by David Kahler, PhD, NYSCF Director of Laboratory Automation, have developed a new way to generate induced pluripotent stem (iPS) cell lines from human fibroblasts, acquired from both healthy and diseased donors.

4 Apr 2013

Research facilitates development of treatments, cures to Alzheimer's disease

A team of researchers at The New York Stem Cell Foundation Research Institute led by Scott Noggle, PhD, Director of the NYSCF Laboratory and the NYSCF - Charles Evans Senior Research Fellow for Alzheimer's Disease, and Michael W. Nestor, PhD, a NYSCF Postdoctoral Research Fellow, has developed a technique to produce three-dimensional cultures of induced pluripotent stem cells called embryoid bodies, amenable to live cell imaging and to electrical activity measurement.

3 Apr 2013

Researchers reprogramming skin cells into brain cells to understand Alzheimer's disease

Sam Gandy, MD, PhD, of the Icahn School of Medicine at Mount Sinai is leading an international team of researchers working to reprogram skin cells into brain cells to gain a better understanding of Alzheimer's disease.

28 Mar 2013

Gladstone investigator to receive Essey Award for fight against amyotrophic lateral sclerosis

Shinya Yamanaka, MD, PhD, a senior investigator at the Gladstone Institutes, next month will receive the Essey Award for his "Commitment to a Cure" from The ALS Association Golden West Chapter.

26 Mar 2013

Embryonic Stem Cell News and Research

Controversy lurks as cloning technique yields embryos with eye on stem cell therapies

UCSF researchers create first functioning human thymus tissue from embryonic stem cells

First Edition: May 16, 2013

Research breakthrough: Human skin cells becomes embryonic stem cells

Modifications in key epigenetic markers influence human embryonic stem cells

Biomedical engineers grow 3D human heart muscle that acts just like natural tissue

Discovery may lead to new treatment for neurodevelopmental, neurodegenerative disorders

Study reveals how the properties of embryonic stem cells are controlled

Newly discovered ‘master regulator’ gene may help develop novel treatment for drug-resistant tumors

CHOP research offers insights into epilepsy, schizophrenia, other neuropsych disorders

ACT announces European phase I clinical trial for Stargardt's disease using retinal pigment epithelial cells

Individual hydroxymethylcytosine molecules in DNA detected by new method involving chemical modification and nanopore analysis

Study: Stem cell transplant heals neurological deficits in mice

Researchers transform skin cells directly into oligodendrocyte precursor cells

Junk DNA plays important role in brain development

New research reveals how autophagy keeps neural stem cells to replace damaged brain, nerve cells

Scientists develop a new way to generate induced pluripotent stem cell lines from human fibroblasts

Research facilitates development of treatments, cures to Alzheimer's disease

Researchers reprogramming skin cells into brain cells to understand Alzheimer's disease

Gladstone investigator to receive Essey Award for fight against amyotrophic lateral sclerosis

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