Mole News and Research

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Wistar scientists describe mechanics of oncogene-induced senescence

Researchers from The Wistar Institute explain a new molecular mechanism behind the phenomenon of oncogene-induced senescence. By depriving the cell of the ability to make new nucleotides-the building blocks of DNA molecules-cells can suppress cancer development by forcing a damaged cell into a senescent state, where the cell remains alive yet cannot reproduce.

5 Apr 2013

TP63 gene correlates significantly with worse prognosis of melanoma

Scientists at Queen Mary, University of London have identified a gene present in some melanoma which appears to make the tumour cells more resistant to treatment, according to research published today in the Journal of Experimental Medicine.

19 Feb 2013

Diabetes tests: an interview with Dr. Danielle Stowasser

Diabetes is a serious condition that causes high levels of glucose (a type of sugar) in the blood. There are three main types of diabetes: type 1 and type 2 diabetes, which are lifelong conditions, and gestational diabetes, which only occurs in women during pregnancy.

3 Dec 2012

Biologists determine how blind mole rats fight off cancer

Biologists at the University of Rochester have determined how blind mole rats fight off cancer-and the mechanism differs from what they discovered three years ago in another long-lived and cancer-resistant mole rat species, the naked mole rat.

6 Nov 2012

Tips to check for skin cancer

Skin cancer is the most common cancer in the United States and finding spots that could be cancerous is as simple as looking at your skin. Now a new video, "Skin Self-Exam: How to Do," from the American Academy of Dermatology demonstrates how to check your skin and what to look for.

10 Oct 2012

HbA1c converter tool launched by NPS

NPS MedicineWise has launched a new online HbA1c converter tool to help people with diabetes understand changes to the way their HbA1c test results are reported in Australia.

10 Oct 2012

Transplant recipients and lymphoma patients far likelier to develop melanoma

Melanoma is on the rise nationally, and transplant recipients and lymphoma patients are far likelier than the average person to get that form of skin cancer and to die from it, a Mayo Clinic review has found.

5 Oct 2012

Mailed sun protection kits lead to higher frequency of sun protective behaviors

A blistering sunburn during childhood or adolescence more than doubles the adult risk of skin cancer. The accumulation of long-term sun exposure may be equally dangerous.

24 Sep 2012

New findings on how naked mole-rats adapt to acidic environments

Naked mole-rats evolved to thrive in an acidic environment that other mammals, including humans, would find intolerable. Researchers at the University of Illinois at Chicago report new findings as to how these rodents have adapted to this environment.

24 Sep 2012

Study estimates drug concentrations of Truvada and tenofovir to reduce risk of HIV among MSM

Several large clinical trials have demonstrated that a daily oral dose of one or two antiretroviral drugs used to treat HIV infection can prevent infection in an approach known as pre-exposure prophylaxis, or PrEP.

15 Sep 2012

World experts shed light on the extent of dangers of night-time artificial lighting

"The most important thing for us is to raise awareness of the dangers of artificial light at night and we have already come a long way now that the American Medical Association (AMA) recently announced its new policy recognizing adverse health effects of exposure to light at night and encouraging further research into the matter," said Prof. Abraham Haim, a leading authority on light pollution, who coordinated the 21st International Congress of Zoology (ICZ) that was held last week at the University of Haifa, Israel.

12 Sep 2012

Germline BAP1 mutations associated with novel cancer syndrome

University of Hawai'i Cancer Center researchers have discovered germline BAP1 mutations are associated with a novel cancer syndrome characterized by malignant mesothelioma, uveal melanoma, cutaneous melanoma and atypical melanocytic tumors. Germline mutations are hereditary gene defects that are present in every cell.

7 Sep 2012

Melanoma manifests differently in children than in adults

Melanoma, newly diagnosed in more than 76,000 Americans in 2011, is the most common and dangerous form of skin cancer. Melanoma is rare in children, accounting for 1 to 4 percent of all melanoma cases and just 3 percent of pediatric cancers. Just as adult cases of melanoma are increasing, pediatric melanoma is rising at the rate of 1 to 4 percent per year.

7 Sep 2012

First Edition: August 21, 2012

Today's headlines include reports from the campaign trail, where House candidates are turning up the Medicare debate; and from the health care marketkplace, where Aetna acquired Coventry Health, a Medicare and Medicaid insurer.

21 Aug 2012

Rodents may hold the key to long and active lifespan

Compared to the average three year life span of a common rat, the 10 to 30 year life of the naked mole rat, a subterranean rodent native to East Africa, is impressive. And compared to the human body, the body of this rodent shows little decline due to aging, maintaining high activity, bone health, reproductive capacity, and cognitive ability throughout its lifetime. Now a collaborative of researchers in Israel and the United States is working to uncover the secret to the small mammal's long - and active - lifespan.

3 Jul 2012

Sun exposure advice recommended for anti-TNF users

Rheumatology patients using antitumor necrosis factor treatment should be given sun exposure education to reduce their risk for skin cancer, say Irish researchers.

2 Jul 2012

Indoor tanning beds banned for minors

Rhode Island took a great step today to protect youth from the dangers of skin cancer by prohibiting the use of indoor tanning beds by minors under the age of 18 without parental consent. This important action is based on significant scientific evidence that indoor tanning is undeniably linked to increased risk of developing melanoma and other forms of skin cancer.

27 Jun 2012

Zebrafish provides insight into human melanoma

A transparent member of the minnow family is providing researchers at Weill Cornell Medical College in New York City with insight into human melanoma - a form of skin cancer - that may lead to new or repurposed drug treatments, for skin and other cancers.

19 Jun 2012

Early skin cancer detection with digital dermoscopy

FotoFinder presents advanced devices for early skin cancer detection at the World Congress of Dermoscopy in Brisbane from May 17 to 19. The new mobile and stationary devices offer better diagnostic accuracy for doctors and more safety for patients. Latest development is the connection of a mobile dermatoscope for iPhone with an online webspace where doctors can request a second opinion on suspicious moles.

17 May 2012

Many men do not protect their skin from sun exposure

As everyone knows, growing older brings an increased number of health concerns. In fact, dermatologists warn that men older than 50 have an increased risk of developing melanoma - the deadliest form of skin cancer.

15 May 2012