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Deep brain stimulation rewires brain circuits linked to depression

Researchers from the Icahn School of Medicine at Mount Sinai have uncovered the first direct evidence that deep brain stimulation (DBS) can remodel white matter pathways in the brain and alter communication across large-scale neural networks, revealing a previously unrecognized mechanism that may explain how the therapy helps patients recover from severe depression.

1 Jun 2026

New brain probe simultaneously records and controls neuron activity

A new breakthrough technology, co-developed by UCL scientists, that simultaneously records and manipulates neuron activity deep within the brain could transform our understanding of neural circuits and neurological conditions, such as Alzheimer's disease and schizophrenia.

1 Jun 2026

Researchers uncover new clues about the origin of Alzheimer's tau tangles

Researchers at Columbia University have uncovered new clues about the earliest molecular events that may trigger Alzheimer's disease, shedding light on how toxic tau filaments begin to form in the brain.

29 May 2026

Gladstone scientists track exact routes used to clear brain waste

Think of the brain as if it were a house. Insulated from its environment, a house relies on complex networks-pipes, drains, and disposal systems-that interface with the outside world to keep the home functional on the inside.

29 May 2026

Grant funds research into molecular memories behind exaggerated fear

Experiencing a traumatic event sometimes produces long-lasting biological changes that can lead to an exaggerated fear response to future stressful events, such as what occurs in individuals with post-traumatic stress disorder (PTSD).

29 May 2026

Harnessing human brain cells to create biocomputers

JMIR Publications today released a feature story on the emerging field of biocomputing in its News and Perspectives section.

29 May 2026

UCLA researchers identify brain circuit controlling memory organization

When a person has a new experience, their brain faces a subtle but critical decision: should this experience be categorized with other stored memories, or should it be filed away as its own new memory? Getting it right allows the brain to help people navigate the world.

28 May 2026

New nutrient-sensing mechanism offers hope for neurodegenerative diseases

Researchers from the University of Cambridge highlight new ways that neurons and many cell types use to sense nutrients - opening potential novel therapeutic avenues for disorders such as Alzheimer's and Parkinson's disease.

28 May 2026

Scientists uncover unexpected thermal retention properties inside the cell

Living cells cool much slower than our current understanding of heat conduction can explain, according to new research from the University of Tokyo. Researchers used two techniques - high-speed temperature mapping and artificial heating - to observe how heat dissipated from living cells and similar-sized artificial, fluid-filled sacs (liposomes).

28 May 2026

Miniature lab grown circuits unlock hidden recovery paths for paralysis

Cambridge scientists have grown miniature circuits in the lab that mimic how the brain and spinal cord connect up, which underlies our movements. They used this model to show how damage to these connections previously considered 'irreversible' could, in fact, be reversible.

28 May 2026

Smaller nanoplastics trigger stronger changes in brain neuron activity

Smaller plastic particles have more effects on neurons, the key information processing cells of the brain, new research from the University of Eastern Finland shows.

27 May 2026

Estrogen decline alters brain cell matrix in older females

A largely overlooked space between cells in women's brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study.

26 May 2026

Neural progenitor timing influences formation of distinct brain layers

The outer regions of the brain, the cortex, have specific layers of different cells - neurons - that are similarly ordered among all mammals, from tiny mouse brains to huge elephant brains.

26 May 2026

NIH researchers discover how weight-loss drugs alter brain cells

A team of researchers at the National Institutes of Health (NIH) have unveiled new details about the events GLP-1 receptor agonists trigger within neurons, which have been largely unexplored until now.

22 May 2026

Lab-grown brain models reveal how epilepsy drug alters fetal development

It is known that the antiepileptic drug valproate increases the risk of developmental disorders in unborn children.

22 May 2026

New study shows how exercise hormone reduces multiple sclerosis symptoms

A new study offers clues as to why exercise can improve neurological symptoms in people with multiple sclerosis (MS).

21 May 2026

Key neural circuit helps the brain “change gears”

Most people have experienced the feeling: switching from one task to another, only to find the brain momentarily stuck in the old mode of thinking. Sometimes, even after realizing a strategy no longer works, the mind keeps returning to it anyway.

21 May 2026

Brain cell division errors may drive cancer and developmental disorders

University of Virginia School of Medicine scientists have revealed how mistakes in the final step of cell division can have dire consequences for developing brain cells.

20 May 2026

Scientists link schizophrenia risk gene to early cortical neuron changes

Researchers at King's College London have identified the biological nature and timing of changes in human cortical neurons caused by altering activity of a schizophrenia-associated gene in developing human neurons.

20 May 2026

New AI framework maps systemic obesity damage at cellular resolution

Researchers at Helmholtz Munich, the Ludwig Maximilians University Munich (LMU) and collaborating institutions have developed an artificial intelligence (AI) framework that maps disease-related changes throughout the entire mouse body at cellular resolution.

20 May 2026