Nuclear Magnetic Resonance (NMR) News and Research

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Small molecule may be able to convince damaged nerves to effectively rewire circuits

Frogs, dogs, whales, snails can all do it, but humans and primates can't. Regrow nerves after an injury, that is—while many animals have this ability, humans don't.

6 Aug 2014

Engineers create truly portable device for nuclear magnetic resonance spectroscopy

A team of engineers at the Harvard School of Engineering and Applied Sciences (SEAS), Schlumberger-Doll Research Center in Cambridge, Mass., and the University of Texas, Austin, have created a truly portable device for nuclear magnetic resonance (NMR) spectroscopy.

5 Aug 2014

Researchers at NIH-FEI Living Lab for Structural Biology achieve breakthrough biological results

FEI is pleased to announce that researchers at the NIH-FEI Living Lab for Structural Biology have achieved breakthrough biological results, using FEI’s Titan Krios™ transmission electron microscope (TEM), to elucidate the structural mechanism by which glutamate receptors participate in the transmission of signals between neurons in the brain. Their work is described in Nature, “Structural Mechanism of Glutamate Receptor Activation and Desensitization,” by Meyerson, et al., (DOI: 10.1038/nature13603), http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13603.html .

From Thermo Fisher Scientific – Electron Microscopy Solutions 4 Aug 2014

Dynamic nuclear polarization: an interview with Professor Robert Griffin, Massachusetts Institute of Technology

DNP, or dynamic nuclear polarization, is an NMR technique which transfers polarization from the electron spins onto the nuclear spins, using constant microwave irradiation to enable the transfer.

From Bruker BioSpin Division 24 Jul 2014

Researchers reveal molecular interplay between Roquin and RNA

The Roquin protein, discovered in 2005, controls T-cell activation and differentiation by regulating the expression of certain mRNAs. In doing so, it helps to guarantee immunological tolerance and prevents immune responses against the body's own structures that can lead to autoimmune disease.

16 Jul 2014

Study to understand molecular interplay between Roquin and RNA to treat autoimmune diseases

Scientists at the Helmholtz Zentrum München, the Ludwig-Maximilians University of Munich (LMU) and the Technische Universität München (TUM) have moved an important step closer to understanding molecular mechanisms of autoimmune diseases.

14 Jul 2014

NMR Spectroscopy for In-Vitro Diagnostic Research

An interview with Dr. Manfred Spraul, discussing AVANCE, an advanced NMR spectrometer that is being applied to the fields of epidemiology and metabolomics.

From Bruker BioSpin Division 2 Jul 2014

Use of NMR in diagnostic research: an interview with Elaine Holmes, Imperial College

The Phenome Center developed out of the Olympic drug testing facility, and we've adapted it so that we use NMR spectrometry, which we have three spectrometers, and mass spectrometry, to take blood and urine from hundreds and thousands of people and profile them to get a biochemical fingerprint of every person.

From Bruker BioSpin Division 1 Jul 2014

NIST produces specialized xenon gas used in biomedical analysis, medical imaging

A chip-scale device that both produces and detects a specialized gas used in biomedical analysis and medical imaging has been built and demonstrated at the National Institute of Standards and Technology (NIST).

23 May 2014

Molecular imaging and multimodality: an interview with Professor Silvio Aime, University of Turin

Molecular imaging aims at the visualization of molecules or molecular events that occur at the cellular level. Clearly it also allows the possibility of looking inside the biochemical pathway at the cellular level and therefore enables us to look at the onset of diseases well before they are resolved into structural change.

From Bruker BioSpin Division 12 May 2014

Researchers develop new technique for discovering natural compounds that form basis of novel therapeutic drugs

Researchers at Griffith University's Eskitis Institute have developed a new technique for discovering natural compounds which could form the basis of novel therapeutic drugs.

17 Apr 2014

Professor from INRS receives NIH grant to explore biomedical potential in field of oncology

Professor Nicolas Doucet of the Centre INRS-Institut Armand-Frappier has just received a research grant from the National Institutes of Health (NIH) in the amount of nearly US$600,000. The 5-year grant is to pursue cutting-edge research in the workings of tiny proteins called RNases and to explore their biomedical potential in the field of oncology as well as in inflammation and asthma.

17 Apr 2014

Newly identified protein markers have potential to contribute to better understanding of heart disease

Researchers at the Intermountain Medical Center Heart Institute in Murray, Utah, have discovered that elevated levels of two recently identified proteins in the body are inflammatory markers and indicators of the presence of cardiovascular disease.

31 Mar 2014

Bruker’s new TopSolids™ software provides accelerated workflow in solid-state NMR for the characterization of protein structures

At Pittcon 2014, Bruker introduced TopSolids™, a new intuitive, workflow-based software package for solid-state NMR in structural biology that provides menu-based, automated setup and acquisition of the most advanced multinuclear multi-dimensional NMR experiments.

5 Mar 2014

New scientific blood analysis predicts short-term mortality in humans

The general state of a person's metabolism can be diversely illustrated with a new scientific blood analysis. With the aid of the analysis biomarkers predicting short-term mortality have now been discovered

26 Feb 2014

New algorithm separates signals into individual frequencies using minimal number of samples

The fast Fourier transform, one of the most important algorithms of the 20th century, revolutionized signal processing. The algorithm allowed computers to quickly perform Fourier transforms - fundamental operations that separate signals into their individual frequencies - leading to developments in audio and video engineering and digital data compression.

12 Dec 2013

Diagnosing colonic polyps: an interview with Dr. Haili Wang, Metabolomic Technologies Inc. (MTI)

Colorectal cancer is a leading cause of death in North America, but it is preventable if found at the colonic polyp stage. Currently, only 39% of colorectal cancer cases in the US are diagnosed at an early and treatable stage.

28 Nov 2013

Bruker to hold NMR webinar in late November

One of the world's leading analytical instrumentation companies is presenting an educational webinar on nuclear magnetic resonance (NMR) later this month.

From Bruker BioSpin Division 5 Nov 2013

Thermo Scientific launches picoSpin 80 portable NMR spectrometer for benchtop operation

Academic and industrial laboratories can now easily collect routine high-resolution nuclear magnetic resonance (NMR) data on molecules in solution using the Thermo Scientific picoSpin 80, a portable, competitively-priced NMR spectrometer built for benchtop operation.

10 Oct 2013

UCSB study demonstrates new tool to resolve structure of membrane proteins

Membrane proteins are responsible for transporting chemicals and messages between a cell and its environment. But determining their structure has proved challenging for scientists. A study by UC Santa Barbara's Han Research Group demonstrates a new tool to resolve the structure of membrane-embedded and membrane-associating proteins using the water dynamics gradient they found across and above the lipid bilayer as a unique ruler.

1 Oct 2013