Nuclease News and Research

RSS

More efficient gene targeting improves prospects for gene therapy

The Nobel prize-winning MRC scientist Sir Aaron Klug and a team from an American company, Sangamo BioSciences, have announced a new way to target genes that may revolutionise medical research and pave the way for new treatments.

20 Mar 2008

A nanoplasmonic molecular ruler for measuring nuclease activity and DNA footprinting

The interactions between proteins and nucleic acids play a critical role in some of life’s most crucial biochemical processes, including gene expression and protein production, and some promising anticancer agents exert their effects by interfering with these interactions.

16 Oct 2006

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing

A team of scientists from Lawrence Berkeley National Laboratory and the Scripps Research Institute has determined the crystal structure and molecular mechanisms of a key part of WRN, a protein that protects humans from premature aging and cancer.

23 Apr 2006

Protein called CPSF73 performs a necessary step in the production of human chromosomes

The study found that a protein called CPSF73 acts like scissors to cut strands of histone messenger RNA (mRNA) in the cell nucleus. This cutting action produces the mRNA needed to create histone proteins that combine with DNA to form chromosomes.

12 Oct 2005

Innovative computer modeling technique predicts how protein molecule behavior in response to environmental conditions

In a development that could have great significance for efforts to understand how the basic molecular machinery of life works, researchers at the University of Texas Medical Branch at Galveston (UTMB) have successfully applied an innovative computer modeling technique to predicting how protein molecules will behave in response to different environmental conditions.

15 Mar 2005

Nuclease News and Research

More efficient gene targeting improves prospects for gene therapy

A nanoplasmonic molecular ruler for measuring nuclease activity and DNA footprinting

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing

Protein called CPSF73 performs a necessary step in the production of human chromosomes

Innovative computer modeling technique predicts how protein molecule behavior in response to environmental conditions

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News