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Scientists uncover new molecular mechanism driving gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract, with KIT mutations driving approximately 75% to 80% of cases.

23 Jun 2026

Gut fungi play key role in pediatric allergic diseases development

Two new studies jointly published in Nature: The Clinical Microbiome reveal that certain species of fungi in the gut play a key role in the development of immune dysregulation and some pediatric allergic diseases - and may be promising targets for new therapies.

23 Jun 2026

New study identifies brain circuits behind spontaneous and voluntary laughter

Laughter is a universal social signal that connects us with others, but the brain regions underlying laughter are not well understood, in part because it's hard to elicit genuine laughter in the lab.

23 Jun 2026

Researchers identify molecular cause of age-related cognitive decline

A research team from University Hospitals, Case Western Reserve University and the Louis Stokes Cleveland VA Medical Center has identified a critical molecular cause of age-related cognitive decline, potentially paving the way for new treatments to protect brain health as we age.

23 Jun 2026

Aligned heart rates indicate real-world social connection and engagement

When people are close-both physically and emotionally-their heart rates begin to align, rising and falling together. Could such cardiac alignment be used as a way to measure social engagement and connection in everyday settings? Hanlu He and colleagues used data collected by 72 students visiting New York City as part of an audio engineering competition.

23 Jun 2026

UCI Health launches world's first embryonic stem cell trial for Huntington's disease

UCI Health, the clinical enterprise of the University of California, Irvine, has opened the world's first in-human embryonic stem cell-derived clinical trial for Huntington's disease.

23 Jun 2026

Accelerated biological aging may drive rising early-onset cancer risk

Cancer is often considered a disease of aging. Older adults are at higher risk because they have had more time to accumulate cellular damage that can trigger tumor formation.

22 Jun 2026

Most adults with depression favor informal community peer support

As mental health needs continue to rise in Singapore, researchers from Duke-NUS Medical School, working with collaborators, including the Institute of Mental Health (IMH), have found that most adults living with symptoms of anxiety or depression are open to receiving support from peers, even if they have not sought professional help.

22 Jun 2026

Study identifies risk factors for early-onset colorectal cancer

A recent study found that factors such as a person's birthweight, sex, ethnicity, and father's age may affect the risk of being diagnosed with colorectal cancer at a young age.

22 Jun 2026

Mount Sinai study connects social determinants of health to disease risks

A new study from the Icahn School of Medicine at Mount Sinai shows that social determinants of health-including environmental conditions, health behaviors, access to resources, and social well-being-can play an equally important or even greater role than genetics in predicting a person's risk of developing common diseases.

22 Jun 2026

GLP-1 medications may lower risk of multiple substance use disorders

A new study led by researchers at The University of Texas at El Paso found that use of weight loss drugs like Ozempic and other GLP-1s is associated with a lower risk of developing alcohol, opioid, nicotine and cocaine use disorders.

21 Jun 2026

Study urges whole-system approach to strengthen global healthcare delivery

Global health policymakers should focus on the way entire healthcare systems work together - improving one element does not always create better outcomes if the wider system is not ready.

21 Jun 2026

Scientists find mechanism behind bird flu infections in dairy cattle

When H5N1 bird flu first began infecting U.S. cattle in early 2024, diagnosis was elusive, because in cows, the disease looked completely different.

19 Jun 2026

Study discovers epigenetic mechanism protecting tooth progenitor cells from stress

An epigenetic "mechanostat" has been discovered that protects tooth-forming progenitor cells from mechanical stress and supports lifelong tissue renewal.

19 Jun 2026

Gene therapy successfully treats deadly childhood liver disease in mice

A new gene therapy has been used to successfully treat a deadly childhood liver disease using mice that model this disease by researchers at UCL and Great Ormond Street Hospital.

19 Jun 2026

Indiana University researchers investigate immune cell aging in Parkinson's disease

A new cutting-edge research team, led by Indiana University School of Medicine scientists and interdisciplinary experts from multiple universities, will investigate the role of immune cell aging on Parkinson's disease risk and progression.

18 Jun 2026

Caregivers experience food insecurity during hospitalization of sick children

Researchers at Wake Forest University School of Medicine found caregivers of children hospitalized for cancer and blood disorders may experience food insecurity during their child's stay, even if they don't face that issue at home, and it could be linked to longer stays.

18 Jun 2026

Healthcare affordability in America drops to lowest level since 2021

New research released today from the West Health-Gallup Center on Healthcare in America finds that fewer than half of Americans (49%) are considered "Cost Secure," meaning they can consistently afford healthcare and prescription medications when and where they need them, the lowest level recorded since West Health and Gallup launched its Healthcare Affordability Index in 2021.

18 Jun 2026

Emergency departments could help boost annual flu vaccination rates

A University of California, Riverside-led study of more than 3,200 emergency department (ED) patients across the United States found that while awareness of influenza vaccination is widespread, most adults seen in EDs are not up to date on their annual flu vaccine.

17 Jun 2026

Cerebral organoid model offers insights into the mechanisms of Ebola virus persistence

Following infection, Ebola virus can survive unnoticed in the human body for months or even years, hiding in areas with little immune surveillance like the central nervous system.

17 Jun 2026