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Clonal hematopoiesis identified as new risk factor for atherosclerosis

To the known risk factors for cardiovascular disease - high blood pressure, high cholesterol, diabetes, overweight and obesity, smoking, and physical inactivity - a new one has to be added: clonal hematopoiesis.

30 Aug 2024

Probenecid shows promise for easing opioid withdrawal symptoms in new study

A deeper understanding of the communication inside the body when someone is going through opioid withdrawal has led to a new clinical trial at the University of Calgary.

29 Aug 2024

New method emulates clinical trial to compare blood thinners for atrial fibrillation

Researchers used real-world clinical data to attempt to emulate a randomized controlled trial testing the effectiveness of two blood thinners, apixaban and warfarin, to prevent stroke in patients with non-valvular atrial fibrillation.

29 Aug 2024

Exploring the role of suvorexant in reducing delirium among older adults

Delirium is a sudden onset and temporary state of disturbed consciousness or cognition, occurring due to underlying medical issues like fever or alcohol withdrawal.

29 Aug 2024

Study explores link between prostate cancer treatment and Alzheimer’s disease

Researchers at the Medical College of Georgia at Augusta University are searching for a better way to understand why many men with prostate cancer end up with Alzheimer's disease, and whether it's the standard hormone therapy treatment or an overactive immune response that actually contributes to the problem.

29 Aug 2024

Georgia Tech study unveils music's role in modulating memory and emotion

The soundtrack of this story begins with a vaguely recognizable and pleasant groove. But if I stop writing and just listen for a second, the music reveals itself completely.

29 Aug 2024

Preventing the spread of superbugs in aged care facilities

There's an urgent need for more careful antibiotic management to protect older people living in residential aged care from the dangerous spread of antibiotic-resistant bacteria or 'superbugs', researchers from Flinders University and SAHMRI warn.

29 Aug 2024

Scientists discover key to activating natural killer cells against cancer

Scientists are on the verge of a cancer breakthrough after working out how the body's immune system targets cells devastated by the disease.

28 Aug 2024

New biomedical device offers hope for patients with chronic pain

Pain is a necessary biological signal, but a variety of conditions can cause those signals to go awry. For people with chronic pain, the root is often faulty signals emerging deep within the brain, giving false alarms about a wound that has since healed, a limb that has since been amputated, or other intricate, hard-to-explain scenarios.

28 Aug 2024

Cell therapy commercialization: Streamline your path to cell therapy commercialization

Moving your cell therapy clinical trial beyond Phase I is an exciting time, marking a significant milestone. There are many therapeutic developers working to address critical patient needs in oncology, auto-immune, regenerative medicine, and other spaces.

From Charles Rivers Laboratories Cell and Gene Therapy 28 Aug 2024

NIH funds study on psychedelics' potential to treat methamphetamine addiction

John McCorvy, PhD, Assistant Professor in the Department of Cell Biology, Neurobiology, and Anatomy at the Medical College of Wisconsin (MCW); Adam Halberstadt, PhD, Professor of Psychiatry at the University of California San Diego (UCSD) and Director of the UCSD Center for Psychedelic Research; and Kevin Murnane, PhD, Associate Professor of Pharmacology, Toxicology, and Neuroscience and Director of Basic Science Research for the Louisiana Addiction Research Center at LSU Health Shreveport, were recently awarded a five-year, $2.4 million research grant from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), to uncover critical insights into how psychedelics could be used as a therapeutic to treat methamphetamine addiction.

27 Aug 2024

Exclusive breastfeeding aids postpartum weight loss

A KK Women's and Children's Hospital (KKH) study[1] on breastfeeding practices revealed that among the women who exclusively breastfed, those with high body mass index[2] (BMI) before pregnancy lost more weight than women with a healthy BMI pre-pregnancy.

27 Aug 2024

GluFormer outperforms existing AI models in predicting blood sugar levels

Study introduces GluFormer, a transformer-based generative model, to predict glycemic patterns using continuous glucose monitoring data, with significant implications for diabetes management and treatment strategies.

26 Aug 2024

Telehealth mindfulness interventions significantly improve chronic pain outcomes for veterans

Scalable telehealth mindfulness-based interventions (MBIs) effectively improve pain-related function and biopsychosocial outcomes in veterans with chronic pain compared to standard care. The study confirms that low-cost, non-pharmacological treatments like MBIs can be accessible and beneficial via telehealth platforms.

25 Aug 2024

Risankizumab outperforms ustekinumab in treating moderate-to-severe Crohn’s disease

Researchers compare the therapeutic efficacy of risakizumab and ustekinumab for the treatment of moderate-to-severe Crohn’s disease.

23 Aug 2024

Olaparib effective against BRCA2-mutated prostate cancer

The anti-cancer drug olaparib may be effective in treating biochemically recurrent prostate cancer without accompanying hormone therapy for men who have mutations in genes such as BRCA2, according to results of a phase II clinical trial of 51 patients conducted at the Johns Hopkins Kimmel Cancer Center and three other sites.

23 Aug 2024

Anti-obesity medication may help to prevent heart attacks and other major cardiac events

The anti-obesity medication semaglutide may help to prevent heart attacks and other major adverse cardiac events among overweight people who have cardiovascular disease, whether or not they also have heart failure, according to a new study led by UCL's Professor John Deanfield.

22 Aug 2024

New research challenges belief that weight loss drugs only reduce appetite

A study carried out in St Vincent's University Hospital (SVUH) Dublin challenges the belief that weight loss medications such as Ozempic, Wegovy or Monjaro work just by promoting satiety and making you eat less.

22 Aug 2024

Camu-camu extract reduces liver fat in non-alcoholic fatty liver disease

A research team from Université Laval has shown the benefits of camu-camu on non-alcoholic fatty liver disease, which affects over seven million people in Canada.

21 Aug 2024

Robotic postural stand training with epidural stimulation benefits trunk control during standing

Kessler Foundation researchers have published a new clinical study investigating the effects of robotic postural stand training combined with spinal cord epidural stimulation (Stand-scES) on trunk control in individuals with high-level spinal cord injury (SCI).

21 Aug 2024