Clinical Trial News and Research

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Precise intensity-modulated radiotherapy outperforms 3D-CRT in advanced lung cancer

Results from a new study led by researchers at The University of Texas MD Anderson Cancer Center support standard use of the more precise intensity-modulated radiotherapy (IMRT) over the alternative 3D-conformal radiotherapy (3D-CRT) for patients with unresectable, locally advanced non-small cell lung cancer (NSCLC).

27 Jun 2024

$Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers$

Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers

Patients with treatment-refractory cancers who received eligibility and testing waivers to participate in a large basket/umbrella oncology trial had similar rates of clinical benefit and adverse events as patients who participated in the trial without waivers.

27 Jun 2024

Study reveals exercise and GLP-1 RA combination preserves bone health during weight loss

Combining exercise with GLP-1 RA liraglutide results in significant weight loss while preserving bone health in adults with obesity.

27 Jun 2024

Tai Chi and cognitive behavioral therapy can reduce insomnia, inflammation in breast cancer survivors

New research led by UCLA Health confirms that both Tai Chi and cognitive behavioral therapy can reduce insomnia in breast cancer survivors but also may provide additional health benefits by reducing inflammation and bolstering anti-viral defenses.

26 Jun 2024

NIAID scientists discover probiotic treatment for eczema

NIAID research has led to the availability of a new over-the-counter topical eczema probiotic.

26 Jun 2024

Lenacapavir: A breakthrough in long-acting HIV prevention for cisgender women

The injectable antiretroviral drug lenacapavir was safe and 100% effective as long-acting HIV pre-exposure prophylaxis (PrEP) among cisgender women in a Phase 3 clinical trial, according to top-line findings released by Gilead Sciences, Inc., the study sponsor.

26 Jun 2024

Chemotherapy's cognitive side effects tied to gut microbiome disruption

Chemotherapy is known to cause behavioral side effects, including cognitive decline. Notably, the gut microbiome communicates with the brain to affect behavior, including cognition.

26 Jun 2024

Methylphenidate may enhance oculomotor function in individuals with multiple sclerosis

A pilot study conducted by Kessler Foundation researchers has shown promising results in the use of methylphenidate to enhance oculomotor function in individuals with multiple sclerosis (MS).

26 Jun 2024

Review finds no proven clinical benefit to strict salt restriction for patients with heart failure

For decades, it's been thought that people with heart failure should drastically reduce their dietary salt intake, but some studies have suggested that salt restriction could be harmful for these patients.

26 Jun 2024

Extended-release ketamine tablets offer new hope for treatment-resistant depression

The BEDROC trial found that extended-release ketamine tablets (R-107) significantly improve depressive symptoms in treatment-resistant depression patients, with the 180 mg dose showing the most efficacy. The treatment was well-tolerated with minimal side effects.

26 Jun 2024

Prunes may protect bone structure and strength in postmenopausal women, study reveals

Dairy isn't the only food that's good for bone health. Prunes may also protect bone structure and strength in postmenopausal women, according to a new study led by Penn State researchers.

25 Jun 2024

New curative treatment for sickle cell disease shows promising results in international trial

Vanderbilt University Medical Center (VUMC) researchers are touting data from a multicenter, international phase 2 clinical trial showing a new, curative treatment for sickle cell disease (SCD).

25 Jun 2024

Genetic variation in people of African ancestry linked to increased risk of diabetes complications

A genetic variation common in people of African ancestry is associated with an increased risk of complications from diabetes, including diabetic retinopathy, according to a report published June 25 in the journal Nature Medicine.

25 Jun 2024

New research challenges current practices for premature babies

Giving very premature babies high concentrations of oxygen soon after birth may reduce the risk of death by 50 percent, compared to lower levels of oxygen says new research led by University of Sydney researchers.

25 Jun 2024

MicroRNAs shed light on aggressive youthful type 2 diabetes

Type 2 diabetes in young people ages 10 to19 has more than doubled in the past 20 years, yet it remains difficult for physicians to predict who will be diagnosed and who will improve with treatment. A newly published study from the University of Oklahoma shows that measuring the circulating abundance of microRNAs – which affect insulin-producing beta cells in the pancreas – is likely as effective as measuring the level of sugar in the blood for determining how a young person with the condition will fare.

25 Jun 2024

First child receives skull-mounted epilepsy device in UK clinical trial

Oran, who had been having severe epileptic seizures for eight years and often needed resuscitation, was the first child in the UK to have this device implanted at Great Ormond Street Hospital in October 2023, when he was 12 years old.

24 Jun 2024

Mouse studies suggest gestational CBD exposure alters offspring behavior and brain function

Cannabidiol (CBD), one of the active ingredients in cannabis, is thought to be safe as it does not cause a "high".

24 Jun 2024

New ketamine slow-release tablet shows promise in treating severe depression

A new tablet form of ketamine has shown promise in treating severe depression, offering a potential alternative to existing clinic-based treatments that can be expensive and lacking in convenience for some patients.

24 Jun 2024

Ketamine tablets offer new hope for treatment-resistant depression

For those suffering from treatment-resistant depression, the anaesthetic drug ketamine offers hope, but it has side effects and can be costly to access – a University of Otago-led clinical trial may change that.

24 Jun 2024

Researchers win $2.78 million grant to harness AI for precision treatment in rectal cancer

With a new five-year, $2.78 million grant from the National Institutes of Health and National Cancer Institute, researchers at Case Western Reserve University(CWRU), Cleveland Clinic and University Hospitals (UH) will use artificial intelligence (AI) to better treat rectal cancer patients.

24 Jun 2024

Clinical Trial News and Research

Precise intensity-modulated radiotherapy outperforms 3D-CRT in advanced lung cancer

Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers

Study reveals exercise and GLP-1 RA combination preserves bone health during weight loss

Tai Chi and cognitive behavioral therapy can reduce insomnia, inflammation in breast cancer survivors

NIAID scientists discover probiotic treatment for eczema

Lenacapavir: A breakthrough in long-acting HIV prevention for cisgender women

Chemotherapy's cognitive side effects tied to gut microbiome disruption

Methylphenidate may enhance oculomotor function in individuals with multiple sclerosis

Review finds no proven clinical benefit to strict salt restriction for patients with heart failure

Extended-release ketamine tablets offer new hope for treatment-resistant depression

Prunes may protect bone structure and strength in postmenopausal women, study reveals

New curative treatment for sickle cell disease shows promising results in international trial

Genetic variation in people of African ancestry linked to increased risk of diabetes complications

New research challenges current practices for premature babies

MicroRNAs shed light on aggressive youthful type 2 diabetes

First child receives skull-mounted epilepsy device in UK clinical trial

Mouse studies suggest gestational CBD exposure alters offspring behavior and brain function

New ketamine slow-release tablet shows promise in treating severe depression

Ketamine tablets offer new hope for treatment-resistant depression

Researchers win $2.78 million grant to harness AI for precision treatment in rectal cancer

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