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Increasing specific brain fats could be potential strategy for preventing epileptic seizures

Increasing the concentration of specific fats in the brain could suppress epileptic seizures. This is evident from ground-breaking research carried out by the research groups of Professor Patrik Verstreken and Professor Wim Versées.

26 Sep 2016

Broadly neutralizing HIV antibodies open new avenues for development of effective vaccine

A small number of people infected with HIV produce antibodies with an amazing effect: Not only are the antibodies directed against the own virus strain, but also against different sub-types of HIV that circulate worldwide.

26 Sep 2016

Research shows degenerative diseases affecting the retina may be treatable with gene therapy

Researchers have demonstrated the ability to deliver a fully functional copy of the CLN3 gene to stem cells of patients with juvenile NCL, an inherited neurodegenerative disease in which a mutation in the CLN3 gene causes early-onset severe central vision loss.

26 Sep 2016

High levels of dietary zinc increase susceptibility to Clostridium difficile infections

Too much dietary zinc increases susceptibility to infection by Clostridium difficile - "C. diff" - the most common cause of hospital-acquired infections.

26 Sep 2016

Study suggests calorie-restricted diet can protect mice from abdominal aortic aneurysms

Mice placed on a low-calorie diet are less likely to develop abdominal aortic aneurysms, according to a new study in The Journal of Experimental Medicine.

26 Sep 2016

KAUST researchers develop biocompatible nanostructures for use in gene delivery

A tiny therapeutic delivery system that can control the body’s ability to manufacture proteins has been developed by Saudi Arabia's King Abdullah University of Science and Technology (KAUST) researchers.

24 Sep 2016

Antibody drug offers new therapeutic approach for treating AML

An antibody drug that targets a surface marker on cancer stem cells could offer a promising new therapeutic approach for treating acute myeloid leukemia (AML), a form of blood cancer that affects an estimated 50,000 people in Saudi Arabia.

24 Sep 2016

DGIST researchers uncover mechanisms that control appetite during low glucose conditions in the brain

Researchers from Daegu Gyeongbuk Institute of Science and Technology (DGIST) in Korea have uncovered the mechanisms behind the enzyme that controls our appetite in response to low glucose availability in the brain.

24 Sep 2016

Scientist develops way to detect BoNT in biological samples

Many know Botox as a trendy way to get rid of wrinkles, but the popular drug — made from botulinum neurotoxin (BoNT) — can do more than just fill lines.

23 Sep 2016

Yale researchers compare efficacy of four PD-L1 assay tests

In a recent study, a Yale Cancer Center team compared the performance of the four available PD-L1 assay tests.

23 Sep 2016

Skin phenotype of pediatric eczema opens door for personalized treatment of AD in infants

Researchers for the first time have identified the skin phenotype of pediatric eczema or atopic dermatitis (AD) in infants, opening the door for personalized treatment approaches for young children with eczema.

23 Sep 2016

DNA damage caused by smoking may last a lifetime

Results of a study published this week show that the effects of smoking on DNA are wide-reaching and some persist long after a person has stopped smoking. The information gained may help improve our understanding of smoking-related diseases.

23 Sep 2016

Ludwig researchers shed more light on key requirement for function of regulatory T cells

A Ludwig Cancer Research study published online September 5th in Nature Immunology illuminates a key requirement for the function of regulatory T cells—immune cells that play a critical role in many biological processes, from suppressing inflammation and deadly autoimmunity to helping tumors evade immune attack.

23 Sep 2016

Scientists find way to reverse malfunctioning protein clumps involved in ALS

In the quest to understand the driving forces behind neurodegenerative diseases, researchers in recent years have zeroed in on clumps of malfunctioning proteins thought to kill neurons in the brain and spinal cord by jamming their cellular machinery.

22 Sep 2016

Scientists identify potential new way to prevent chronic urinary tract infections

Researchers have identified a potential way to prevent chronic urinary tract infections (UTIs). Their research points to a key protein that bacteria use to latch onto the bladder and cause UTIs, according to scientists at Washington University School of Medicine in St. Louis.

22 Sep 2016

Progesterone treatment protects female mice against consequences of influenza infection

Over 100 million women are on hormonal contraceptives. All of them contain some form of progesterone, either alone or in combination with estrogen.

22 Sep 2016

Bile acid transporter inhibitors can prevent NASH in mice, study shows

Drugs that interfere with bile acid recycling can prevent several aspects of NASH (nonalcoholic steatohepatitis) in mice fed a high-fat diet, scientists from Emory University School of Medicine and Children's Healthcare of Atlanta have shown.

21 Sep 2016

Immune and targeted therapies may be beneficial in patients with melanoma brain metastases

Brain metastases are one of the most common complications of advanced melanoma, requiring multidisciplinary management.

21 Sep 2016

TSRI scientists shed light on molecular workings of MS drug

A study by scientists at The Scripps Research Institute has helped to de-mystify the molecular workings of the multiple sclerosis (MS) drug Tecfidera. The drug is the most widely prescribed pill-based therapy for MS, but its biological mechanism remains mysterious.

21 Sep 2016

Scientists engineer smallest-reported synthetic virus that may help advance gene therapy

Gene therapy is a kind of experimental treatment that is designed to fix faulty genetic material and help a patient fight off or recover from a disease.

21 Sep 2016

G Protein News and Research

Increasing specific brain fats could be potential strategy for preventing epileptic seizures

Broadly neutralizing HIV antibodies open new avenues for development of effective vaccine

Research shows degenerative diseases affecting the retina may be treatable with gene therapy

High levels of dietary zinc increase susceptibility to Clostridium difficile infections

Study suggests calorie-restricted diet can protect mice from abdominal aortic aneurysms

KAUST researchers develop biocompatible nanostructures for use in gene delivery

Antibody drug offers new therapeutic approach for treating AML

DGIST researchers uncover mechanisms that control appetite during low glucose conditions in the brain

Scientist develops way to detect BoNT in biological samples

Yale researchers compare efficacy of four PD-L1 assay tests

Skin phenotype of pediatric eczema opens door for personalized treatment of AD in infants

DNA damage caused by smoking may last a lifetime

Ludwig researchers shed more light on key requirement for function of regulatory T cells

Scientists find way to reverse malfunctioning protein clumps involved in ALS

Scientists identify potential new way to prevent chronic urinary tract infections

Progesterone treatment protects female mice against consequences of influenza infection

Bile acid transporter inhibitors can prevent NASH in mice, study shows

Immune and targeted therapies may be beneficial in patients with melanoma brain metastases

TSRI scientists shed light on molecular workings of MS drug

Scientists engineer smallest-reported synthetic virus that may help advance gene therapy

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