Microbiology News and Research

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Researchers and clinicians share findings on ovarian cancer

After nearly four years of work, a group of researchers and clinicians from the University of Colorado (CU) published a paper this week in the Clinical Cancer Research that shares findings from research looking at how the composition of ovarian cancer tumors changes during chemotherapy and contributes to therapeutic response.

16 Sep 2020

Arizona COVID-19 Genomics Union tracks SARS-CoV-2 genome sequences

Initial findings reported by the Arizona COVID-19 Genomics Union (ACGU) suggest that following Arizona's first reported case of COVID-19 in late January, the state experienced no cases that went undetected and was COVID-free until at least 11 distinct incursions occurred between mid-February and early April.

16 Sep 2020

Treatment with a cannabinoid prevented the development of colon cancers in mice

Inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis are caused by unrestrained inflammation of the gastrointestinal tract.

15 Sep 2020

Researchers identify the missing link in the production of nitric oxide

Some microorganisms, the so-called methanotrophs, make a living by oxidizing methane (CH4) to carbon dioxide (CO2). Ammonia (NH3) is structurally very similar to methane, thus methanotrophs also co-metabolize ammonia and produce nitrite.

14 Sep 2020

Middle-aged adults may be in a perpetual state of H3N2 flu virus vulnerability

Penn Medicine researchers have found that middle-aged individuals -- those born in the late 1960s and the 1970s -- may be in a perpetual state of H3N2 influenza virus susceptibility because their antibodies bind to H3N2 viruses but fail to prevent infections, according to a new study led by Scott Hensley, PhD, an associate professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania.

12 Sep 2020

Danish household SARS-CoV-2 study shows low transmission from children

Using data from the national register in Denmark, researchers studied how likely persons infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmit it within their households. The study found additional household members tested positive in 17% of cases after one person in the household was infected. The research is published on the preprint server medRxiv in September 2020.

11 Sep 2020

Antibiotic molecule helps the body's own immune system to kill HIV infected cells

Ever since the first cases of a mysterious disease in the early 1980s exploded into the HIV/AIDS pandemic, researchers have been searching for ways to outsmart the deadly virus.

11 Sep 2020

Study highlights the importance of considering strain differences when designing therapies

Interferon (IFN) responses are one of the first defenses the body mounts against viral infections, and research has shown that it plays a role controlling viral replication.

11 Sep 2020

Researchers are developing rapid-acting, long-lasting disinfectant spray to kill viruses

Current disinfectant products for killing viruses like coronavirus take minutes to fully sanitize surfaces, which isn't practical on high-contact areas such as door handles, elevators and bannisters.

10 Sep 2020

Study: Without proper public education, wearing masks could lead to more COVID-19 infections

A novel new study suggests that the behavior public officials are now mandating or recommending unequivocally to slow the spread of COVID-19 - wearing a face covering - should come with a caveat. If not accompanied by proper public education, the practice could lead to more infections.

9 Sep 2020

Researchers receive $1.9 million federal grant to find Lyme disease vaccine

Pesky, yet dangerous ticks are no longer latching exclusively onto hunters and outdoor enthusiasts. Milder winters and disrupted habitats have driven them out of the woods, with Lyme disease cases in the United States tripling since the late 1990s.

9 Sep 2020

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

Results from two early-phase Russian non-randomised vaccine trials (Sputnik V) in a total of 76 people are published today in The Lancet, finding that two formulations of a two-part vaccine have a good safety profile with no serious adverse events detected over 42 days, and induce antibody responses in all participants within 21 days.

5 Sep 2020

Study: Small neutralizing antibody can block SARS-CoV-2 from entering human cells

Researchers at Karolinska Institutet in Sweden have identified a small neutralizing antibody, a so-called nanobody, that has the capacity to block SARS-CoV-2 from entering human cells.

4 Sep 2020

Simulation platform teaches students the fundamentals of responses to pandemics

In 2015, a team of specialists in modeling disease outbreaks got together with educators to create Operation Outbreak, an educational platform and simulation intended to teach high school and college students the fundamentals of responses to pandemics.

3 Sep 2020

Dogs' aging mechanism and memory performance linked to gut microbiome composition

Our gut microbiota can crucially influence our behavior and neurodevelopment. New research of the Ethology Department at the Faculty of Science at Eötvös Loránd University indicates that dogs' aging mechanism and memory performance are also linked to their gut microbiome composition.

2 Sep 2020

New microgel drug delivery method could improve effectiveness of pancreatic islet transplants

Pancreatic islet transplants, which revive insulin production to treat type 1 diabetes, only last an average of three years.

31 Aug 2020

New dual CAR T cell immunotherapy shows enhanced therapeutic potency to fight HIV

A recent study published in the journal Nature Medicine, led by researchers Todd Allen, PhD, a professor of Medicine at Harvard Medical School and group leader at the Ragon Institute of MGH, MIT and Harvard, and Jim Riley, PhD, a professor of Microbiology in the Perelman School of Medicine at the University of Pennsylvania, describes a new Dual CAR T cell immunotherapy that can help fight HIV infection.

31 Aug 2020

Thomas Jefferson University receives grant for the development of CoraVax

The Commonwealth of Pennsylvania has announced grants totaling $10M to 23 entities to develop effective COVID-19 vaccines, treatments and therapies.

28 Aug 2020

Study may help explain the symptoms and organs involved with SARS-CoV-2 infection

A study of a gateway receptor for SARS-CoV-2 led by Walter Lukiw, PhD, Professor of Neuroscience, Neurology and Ophthalmology at LSU Health New Orleans' Neuroscience Center of Excellence and School of Medicine, may help explain the wide variety of symptoms and organs involved with SARS-CoV-2 infection and COVID-19.

28 Aug 2020

International researchers study the effects of pathogenic fungus Candida auris

The pathogenic fungus Candida auris, which first surfaced in 2009, is proving challenging to control. It is resistant to many fungicides and not easy to diagnose.

28 Aug 2020

Microbiology News and Research

Researchers and clinicians share findings on ovarian cancer

Arizona COVID-19 Genomics Union tracks SARS-CoV-2 genome sequences

Treatment with a cannabinoid prevented the development of colon cancers in mice

Researchers identify the missing link in the production of nitric oxide

Middle-aged adults may be in a perpetual state of H3N2 flu virus vulnerability

Danish household SARS-CoV-2 study shows low transmission from children

Antibiotic molecule helps the body's own immune system to kill HIV infected cells

Study highlights the importance of considering strain differences when designing therapies

Researchers are developing rapid-acting, long-lasting disinfectant spray to kill viruses

Study: Without proper public education, wearing masks could lead to more COVID-19 infections

Researchers receive $1.9 million federal grant to find Lyme disease vaccine

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

Study: Small neutralizing antibody can block SARS-CoV-2 from entering human cells

Simulation platform teaches students the fundamentals of responses to pandemics

Dogs' aging mechanism and memory performance linked to gut microbiome composition

New microgel drug delivery method could improve effectiveness of pancreatic islet transplants

New dual CAR T cell immunotherapy shows enhanced therapeutic potency to fight HIV

Thomas Jefferson University receives grant for the development of CoraVax

Study may help explain the symptoms and organs involved with SARS-CoV-2 infection

International researchers study the effects of pathogenic fungus Candida auris

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