OCT News and Research

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Huntington's disease impairs autophagy in older patients

Huntington's disease, a fatal, inherited neurodegenerative condition, is caused by a genetic error present at birth, though its symptoms often don't begin until middle adulthood.

28 Oct 2022

Research shows in real time how immune memory cells are stored in the bone marrow

Vaccines work their magic by effectively creating immune cells that are long lived, often for over decades.

28 Oct 2022

Wireless, battery-free pacemaker could make life easier for heart disease patients

Atrial fibrillation – a form of irregular heartbeat, or arrhythmia – leads to more than 454,000 hospitalizations and nearly 160,000 deaths in the United States each year. Globally, it is estimated that approximately 60 million people are affected by the condition.

28 Oct 2022

People with disabilities strongly affected by online microaggressions

In person, people with disabilities often experience microaggressions – comments or subtle insults based on stereotypes. New types of microaggressions play out online as well, according to new Cornell-led research.

28 Oct 2022

CU Anschutz study details the mechanisms behind the link between shingles and strokes

Scientists investigating why people who have had shingles are at a higher risk of stroke, now believe the answer lies within lipid vesicles called exosomes that shuttle proteins and genetic information between cells, according to new research from the University of Colorado Anschutz Medical Campus.

28 Oct 2022

Large listeriosis outbreak in Spain caused by contaminated stuffed pork

Listeria bacteria are ubiquitous in the environment and consumption of food contaminated with Listeria monocytogenes is one of the main routes for food-borne outbreaks.

28 Oct 2022

When monkeypox reaches rural communities, it collides with strained public health systems

When a case of monkeypox was reported in Nevada's Humboldt County in August, it was the state's first detected occurrence of the virus in a rural area. Soon, cases were found in other rural counties — Nye, Lyon, and Elko — posing another hurdle for public health systems that have been worn thin by the covid-19 pandemic.

28 Oct 2022

AI models improve the accuracy of diagnosing coronary artery disease

Several recent discoveries show that the accuracy of diagnosing coronary artery disease and predicting patient risk is improved with the help of artificial intelligence (AI) models developed by scientists in the Division of Artificial Intelligence in Medicine at Cedars-Sinai.

28 Oct 2022

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

Genetic mutations kick start cancers. Some mutations shuffle the genetic code, others come from the deletion of key genes.

28 Oct 2022

Proof-of-principle study: Novel tool advances potential way to deliver gene therapy

Johns Hopkins Medicine researchers say they have successfully used a cell's natural process for making proteins to "slide" genetic instructions into a cell and produce critical proteins missing from those cells.

28 Oct 2022

Researchers unravel the precise mechanism of nuclear envelope repair in human and mouse cells

All living cells harbor nuclei - key biological structures that play an important role in information storage, retrieval, and duplication of genetic information.

28 Oct 2022

Commensal gut microbes from IBD patients produce genotoxic metabolites

Functional screening of human gut microbiota reveals a family of small molecule genotoxins called indolimines in patients with inflammatory bowel disease (IBD), according to a new study.

27 Oct 2022

Ancient viral DNA in human genomes protects cells against present-day viruses

Viral DNA in human genomes, embedded there from ancient infections, serve as antivirals that protect human cells against certain present-day viruses, according to new research.

27 Oct 2022

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

Researchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have used CRISPR/Cas9 technology to engineer donor T cells to try to treat seriously ill children with resistant leukaemia, who had otherwise exhausted all available therapies.

27 Oct 2022

Newly developed chemical compounds show promise as potential anticancer therapy

A University of Kentucky Markey Cancer Center researcher's team developed new chemical compounds that show promise as a potential anticancer therapy to treat aggressive tumors.

27 Oct 2022

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest in response.

27 Oct 2022

Study sheds light on why some patients respond better than others to immunotherapy

Immunotherapy, a biotherapy that boosts the ability of the immune system to recognize and attack mutant tumor cells, has transformed the treatment landscape for patients battling cancer, which emerges from the progressive accumulation of DNA mutations.

27 Oct 2022

OCT News and Research

Huntington's disease impairs autophagy in older patients

Research shows in real time how immune memory cells are stored in the bone marrow

Wireless, battery-free pacemaker could make life easier for heart disease patients

People with disabilities strongly affected by online microaggressions

CU Anschutz study details the mechanisms behind the link between shingles and strokes

Large listeriosis outbreak in Spain caused by contaminated stuffed pork

When monkeypox reaches rural communities, it collides with strained public health systems

AI models improve the accuracy of diagnosing coronary artery disease

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

Proof-of-principle study: Novel tool advances potential way to deliver gene therapy

Researchers unravel the precise mechanism of nuclear envelope repair in human and mouse cells

Commensal gut microbes from IBD patients produce genotoxic metabolites

Ancient viral DNA in human genomes protects cells against present-day viruses

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

Newly developed chemical compounds show promise as potential anticancer therapy

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Study sheds light on why some patients respond better than others to immunotherapy

Seeing or hearing birds linked with an improvement in mental wellbeing

Researchers find a switch to regulate the diabetes-causing gene

Advanced type of nanoparticle could help fight hard-to-treat cancers

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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